Results 61 to 70 of about 1,166,542 (269)

Isolation of amyloidogenic aggregates of transthyretin by ceramic hydroxyapatite chromatography

Journal of Chromatography Open
Amyloidogenic proteins can lapse into unstable monomeric precursors which misfold and self-assemble into toxic oligomers and amyloid aggregates leading to intracellular deposition of insoluble amyloid fibrils, the hallmark of amyloidosis and major ...
Maria K. Tsoumpra, Shintaro Kobayashi, Eri Chatani   +2 more
doaj   +1 more source

Rapid and column-chromatography-free peptide chain elongation via a one-flow, three-component coupling approach

, 2023
Naoto Sugisawa, Akira Ando, Shinichiro Fuse   +2 more
openalex   +2 more sources

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Seasonal Variation of the Chemical Composition and Antimicrobial and Cytotoxic Activities of the Essential Oils from Inga laurina (Sw.) Willd.

Molecules, 2014
The seasonal chemical composition of essential oils from Inga laurina was determined by GC/MS. In the stem bark’s essential oil extracted during the dry season, the presence of terpenoids (30.05%) stood out, and phytol (9.76%) was the major compound ...
Fabiana B. Furtado, Francisco J. T. de Aquino, Evandro A. Nascimento, Carla de M. Martins, Sérgio A. L. de Morais, Roberto Chang, Luís C. S. Cunha, Luís F. Leandro, Carlos H. G. Martins, Mário M. Martins, Claudio V. da Silva, Fabrício C. Machado, Alberto de Oliveira   +12 more
doaj   +1 more source

Validation and Optimization of Ultrasound-Assisted Dispersive LiquidLiquid Microextraction as a Preparation Method for Detection of Methadone in Saliva with Gas Chromatography-Mass Spectrometry Technique [PDF]

, 2020
Ahmad Shekari, Mehdi Forouzesh, Roohollah Valipour, Fardin Fallah, Pardis Shojaei   +4 more
openalex   +1 more source

Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium

FEBS Open Bio, EarlyView.
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita, Toyonobu Usuki, Robert R. Kay, Tamao Saito   +3 more
wiley   +1 more source

A perspective on the use of deep deterministic policy gradient reinforcement learning for retention time modeling in reversed-phase liquid chromatography

, 2023
Alexander Kensert, Gert Desmet, Deirdre Cabooter   +2 more
openalex   +2 more sources

Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein

FEBS Open Bio, EarlyView.
This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley   +1 more source

Current chromatographic methods to determine cannabinoids in biological samples: A review of the state-of-the art on sample preparation techniques

Green Analytical Chemistry
Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) are the primary compounds of interest in the plant cannabis sativa, used mainly as recreational drug.
Igor Gustavo Carvalho Oliveira, Caroline Fernandes Grecco, Israel Donizeti de Souza, Maria Eugênia Costa Queiroz   +3 more
doaj   +1 more source

Size‐exclusion chromatography‐based enrichment of extracellular vesicles from urine samples [PDF]

, 2015
Inés Lozano‐Ramos, Ioana Bancu, Anna Oliveira‐Tercero, María Pilar Armengol, Armando Menezes‐Neto, Hernando A. del Portillo, Ricardo Lauzurica‐Valdemoros, Francesc E. Borràs   +7 more
openalex   +1 more source