Chromogranin A and chromogranin B in pancreatic neuroendocrine tumors
For the first time in Russia a comparative study of chromogranin A (CgA) and chromogranin B (CgB) in neuroendocrine tumors (NETs) of the pancreas was performed. We examined 50 primary patients with pancreatic NETs and 42 healthy people. The determination of CgA and CgB was performed in blood serum using standard enzyme-linked immunoassay test-systems ...
N. V. Lyubimova +3 more
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Aberrant synaptophysin expression in classic Hodgkin lymphoma
Background Synaptophysin is an immunohistochemical marker for neuroendocrine differentiation and is widely used in pathologic diagnosis. Its expression in malignant lymphoma has not yet been described.
Soyoung Im +3 more
doaj +1 more source
Oral Plasmablastic Lymphoma: A Case Report of an HIV Negative Patient with an Unusual Clinical Signature [PDF]
Plasmablastic Lymphoma (PBL) is an aggressive variant of diffuse large B-cell lymphoma with a low survival rate. It is associated with Human Immunodeficiency Virus (HIV) infection but also affects patients with autoimmune diseases as chronic lymphocytic
Pamela Pignatelli +4 more
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Duodenal carcinoid tumour – a case report [PDF]
Duodenal carcinoids are rare tumours of the small intestine with heterogenous clinical and pathological characteristics. The long-term prognosis is very good if discovered in the early stages.
Alexescu, Teodora Gabriela +7 more
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Cellular distribution and amount of chromogranin A in bovine endocrine pancreas [PDF]
We determined the cellular distribution and the amount of chromogranin A in endocrine cells of bovine pancreas using a polyclonal antibody against bovine adrenomedullary chromogranin A. The relative amounts of chromogranin A in the different cells of the
Ehrhart, M. +3 more
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As a major component of the enteroendocrine system, enterochromaffin (EC) cells play a key role in ulcerative colitis (UC). However, the scarcity of EC cells has limited the investigation of their function.
Dongping Lyu +22 more
doaj +1 more source
Immunological characterization of chromogranins A and B and secretogranin II in the bovine pancreatic islet [PDF]
Antisera against chromogranin A and B and secretogranin II were used for analysing the bovine pancreas by immunoblotting and immunohistochemistry. All three antigens were found in extracts of fetal pancreas by one dimensional immunoblotting. A comparison
A Iacangelo +44 more
core +1 more source
Effects of pH and Ca2+ on Heterodimer and Heterotetramer Formation by Chromogranin A and Chromogranin B [PDF]
The two major proteins of the secretory vesicles of neuroendocrine cells, chromogranin A (CGA) and chromogranin B (CGB), have been shown to undergo pH- and Ca2+-dependent conformational changes and aggregation and have been suggested to play essential roles during secretory vesicle biogenesis in the trans-Golgi network.
S H, Yoo, M S, Lewis
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Analysis of thyroid carcinomas with immunohistochemical panel application: retrospectively study of 52 cases [PDF]
Aim: The aim of this study was to share our cases of thyroid carcinoma with the literature and to emphasize the importance of evaluation with an immunohistochemical panel in cases with difficulty in the differential diagnosis.
Mecdi Gurhan Balci, Mahir Tayfur
doaj +1 more source
Ca2+ binding to Chromaffin Vesicle Matrix Proteins [PDF]
Recently we found that Ca2+ within chromaffin vesicles is largely bound [Bulenda, D., & Gratzl, M. (1985) Biochemistry 24, 7760-77651. In order to explore the nature of these bonds, we analyzed the binding of Ca2+ to the vesicle matrix proteins as well ...
Gratzl, Manfred, Reiffen, F. U.
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