Natural History and Management of Familial Paraganglioma Syndrome Type 1: Long-Term Data from a Large Family [PDF]
, 2020 Head and neck paragangliomas are the most common clinical features of familial paraganglioma syndrome type 1 caused by succinate dehydrogenase complex subunit D (SDHD) mutation. The clinical management of this syndrome is still unclear.
Cantisani, Vito +12 more
core +1 more source
Expression-Based Genome-Wide Association Study Links Vitamin D-Binding Protein With Autoantigenicity in Type 1 Diabetes. [PDF]
, 2016 Type 1 diabetes (T1D) is caused by autoreactive T cells that recognize pancreatic islet antigens and destroy insulin-producing β-cells. This attack results from a breakdown in tolerance for self-antigens, which is controlled by ectopic antigen expression
Butte, Atul J +9 more
core +1 more source
The Prohormone VGF Regulates β Cell Function via Insulin Secretory Granule Biogenesis
Cell Reports, 2017 The prohormone VGF is expressed in neuroendocrine and endocrine tissues and regulates nutrient and energy status both centrally and peripherally. We and others have shown that VGF-derived peptides have direct action on the islet β cell as secretagogues ...
Samuel B. Stephens +6 more
doaj +1 more source
Magnetic resonance and computed tomography imaging of a carotid body tumor in a dog [PDF]
, 2012 A 5-year-old castrated male Labrador Retriever was presented to a referring veterinarian for a swelling in the neck region. Based on the results of histopathology, a carotid body tumor, was diagnosed.
De Cock, Hilde +4 more
core +2 more sources
Fine needle aspiration cytology of hepatic metastases of neuroendocrine tumors: A 20‐year retrospective, single institutional study [PDF]
, 2017 Background Fine needle aspiration (FNA) is considered an excellent technique for documenting metastatic neuroendocrine tumors (NETs). This study aims to evaluate the accuracy of FNA in diagnosing metastatic NETs to the liver and determining the grade ...
Cramer, Harvey +3 more
core +1 more source
The Ion Channel Function of Mouse Chromogranin B [PDF]
Biophysical Journal, 2015 Chromogranins are known to play fundamentally important roles in the biogenesis, acidification and maturation as well as the regulated release of secretory granules in almost all endocrine cells. Elevated level of chromogranin A and B has been biomarkers for multiple different neuroendocrine tumors.
Yadav, Gaya P. +3 more
openaire +1 more source
Elevated serum levels of Chromogranin A in hepatocellular carcinoma
BMC Surgery, 2012 Background During the past three decades, the incidence of hepatocellular carcinoma in the United States has tripled. The neuroendocrine character has been observed in some tumor cells within some hepatocellular carcinoma nodules and elevated serum ...
Biondi Antonio +8 more
doaj +1 more source
PLoS ONE, 2013 PurposeMetastatic neuroendocrine tumors secrete serotonin and other vasoactive substances that are responsible for carcinoid syndrome and carcinoid heart disease.
Rebecca Dobson +15 more
doaj +1 more source
Neoadjuvant chemotherapy with capecitabine and temozolomide for unresectable pancreatic neuroendocrine tumor. [PDF]
, 2012 Pancreatic neuroendocrine tumors (PNETs) are relatively rare tumors that arise in the endocrine cells of the pancreas. Historically, somatostatin analogues have been used in this disease primarily for symptom control and, to a limited extent, disease ...
Devata, Sumana, Kim, Edward J
core +2 more sources
Malignancy within a tail gut cyst:a case of retrorectal carcinoid tumour [PDF]
, 2014 Purpose. Tailgut cysts with malignant transformation are rare entities. We discuss the diagnostic strategy and treatment of a malignancy within a tailgut cyst. Methods.
Abukar, A. A. +7 more
core +7 more sources