Results 81 to 90 of about 30,456 (242)

Potential novel therapy targets in neuroendocrine carcinomas of the breast [PDF]

, 2018
Neuroendocrine carcinoma (NEC) of the breast is a rare, special type of breast cancer, reportedly constituting 2% to 5% of all breast cancers. Although breast NEC does not have a specific targeted therapy, several new targeted therapies based on specific
Contreras, Elma, Florento, Elena, Gatalica, Zoran, Palazzo, Juan, Sanati, Souzan, Swensen, Jeffrey, Vranic, Semir, Xiu, Joanne   +7 more
core   +2 more sources

P19.04.B CHROMOGRANIN A IN HUMAN MENINGIOMAS

Neuro-Oncology
Abstract BACKGROUND Meningiomas are the most common intracranial tumor. The neoplasms are usually benign and slow-growing, but the recurrence rates are substantial. There is currently no established pharmaceutical treatment for patients suffering from meningioma, marking the need for a further ...
Tollefsen, S E, Solheim, O, Mjønes, P, Torp, S H   +3 more
openaire   +2 more sources

Changes in the 6th edition of the World Health Organization classification of tumours of the digestive system

Histopathology, EarlyView.
Changes and new entities in the 6th edition WCT of the digestive system, including structural, molecular, and diagnostic updates to standardize terminology and improve clinical relevance. Epithelial tumours are organized by site; neuroendocrine, mesenchymal and haematolymphoid tumours have dedicated chapters, with refined grading, redefined ...
Mark J Arends, Irene Esposito, Anthony J Gill, Ralph H Hruban, Joseph D Khoury, Motohiro Kojima, Elizabeth A Montgomery, Fatimah Abdulkareem, Fátima Carneiro, Guido Costamagna, Gregory Lauwers, Alexandros D Polydorides, Guido Rindi, Massimo Rugge, Peter Schirmacher, Amitabh Srivastava, James Yao, Jennelle C Hodge, James G Kench, Bharat Rekhi, Miguel Reyes‐Múgica, Antonia R Sepulveda, Chanjuan Shi, Pavitratha Puspanathan, Harshima Wijesinghe, Christine Giesen, Blanca Iciar Indave Ruiz, Dilani Lokuhetty, WCT standing editorial board, Iris D Nagtegaal, Wendy Cooper, Michael Eden, Andrew Field, Vicky Goh, Jennelle Hodge, James Kench, Joseph Khoury, Katia Leite, Zhiyong Liang, Daichi Maeda, George Netto, Bharat Rekhi, Miguel Reyes Múgica, Brian Rous, Ales Ryska, Shahin Sayed, Antonia R Sepulveda, Chanjuan Shi, Gary Tse   +48 more
wiley   +1 more source

Mucosal Neuroendocrine Cell Abnormalities in Patients with Chronic Constipation

Asian Journal of Surgery, 2004
The aim of this study was to examine the distribution of neuroendocrine cells (NEC) in patients with chronic constipation (CC) as a means of establishing a relationship between pathology, symptomatology and treatment.
Akiko Kobayashi, Yasuo Hayashida
doaj   +1 more source

Characterization of hormone and protein release from alpha-toxin- permeabilized chromaffin cells in primary culture [PDF]

, 1986
Addition of Staphylococcus aureus alpha-toxin to adult bovine chromaffin cells maintained in primary culture causes permeabilization of cell membrane as shown by the release of intracellular 86Rb+.
Ahnert-Hilger, G., Aunis, D., Bader, M. F., Gratzl, Manfred, Thiersé, D.   +4 more
core  

Fine needle aspiration cytology of hepatic metastases of neuroendocrine tumors: A 20‐year retrospective, single institutional study [PDF]

, 2017
Background Fine needle aspiration (FNA) is considered an excellent technique for documenting metastatic neuroendocrine tumors (NETs). This study aims to evaluate the accuracy of FNA in diagnosing metastatic NETs to the liver and determining the grade ...
Cramer, Harvey, Saeed, Omer A., Wang, Xiaoyan, Wu, Howard H.   +3 more
core   +1 more source

Natural History and Management of Familial Paraganglioma Syndrome Type 1: Long-Term Data from a Large Family [PDF]

, 2020
Head and neck paragangliomas are the most common clinical features of familial paraganglioma syndrome type 1 caused by succinate dehydrogenase complex subunit D (SDHD) mutation. The clinical management of this syndrome is still unclear.
Cantisani, Vito, Colao, Annamaria, Di Leo, Nicola, Faggiano, Antongiulio, Feola, Tiziana, Giannetta, Elisa, Isidori, Andrea M, Lenzi, Andrea, Modica, Roberta, Polti, Giorgia, Puliani, Giulia, Sesti, Franz, Verrico, Monica   +12 more
core   +1 more source

The role of peripheral serotonin in SARS‐CoV‐2 infectivity, COVID‐19 treatment and long COVID

Immunology &Cell Biology, EarlyView.
In this article, we discuss how SARS‐CoV‐2 infects the gastrointestinal tract, that enterochromaffin cells, the source of circulating serotonin, uniquely express viral entry receptors. We examine how this infection disrupts gut‐derived serotonin, contributing to gastrointestinal symptoms and disease severity, and link elevated plasma serotonin to COVID‐
Daniel W Thorpe, Lauren A Jones, Alyce M Martin, Rosemary A Coleman, Caitlin Allman, Rochelle A Peterson, Damien J Keating   +6 more
wiley   +1 more source

Olfactory neuroblastoma: a rare sinonasal malignancy

Journal of the Pakistan Medical Association
Olfactory neuroblastoma is a rare malignant tumour arising from the olfactory nerve and extending into the nasal cavity. In this case report, the case of a 42-year-old male is presented.
Athar Adnan Uppal, Saira Zaman, Ayesha Shahbaz, Sadia Iram   +3 more
doaj   +1 more source

Treatment options for PNET liver metastases. a systematic review [PDF]

, 2018
Pancreatic neuroendocrine tumors (PNETs) are rare pancreatic neoplasms. About 40-80% of patients with PNET are metastatic at presentation, usually involving the liver (40-93%). Liver metastasis represents the most significant prognostic factor.
Aurello, Paolo, Crovetto, Anna, Debs, Tarek, Mangogna, Livia Maria, Moschetta, Giovanni, Nigri, Giuseppe, Persechino, Raffaello, Petrucciani, Niccolò, Ramacciato, Giovanni   +8 more
core   +1 more source