Results 181 to 190 of about 2,220 (203)
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Chromogranin peptides in brain diseases
Journal of Neural Transmission, 2011Synaptic disturbances may play a key role in the pathophysiology of neuropsychiatric diseases. In this article, we review immunohistological findings of chromogranin peptides in neurodegenerative and neurodevelopmental disorders, with particular emphasis on Alzheimer's disease, the disorder chromogranins have been studied most extensively.
Michael, Willis +3 more
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Chromogranins in Temporal Lobe Epilepsy
Epilepsia, 2000Summary: Purpose: Chromogranins are neuropeptide precursors stored in large dense core vesicles. Because physiological functions have been postulated for peptides originating from chromogranins, we investigated the distribution of chromogranins A and B and secretoneurin (a peptide derived from secretogranin II) in the control and epileptic ...
S, Kandlhofer +6 more
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The granin-(chromogranin/secretogranin) family
Trends in Biochemical Sciences, 1991The chromogranins/secretogranins, referred to in abbreviated form as granins, are a family of acidic secretory proteins that are found in the secretory granules of a wide variety of endocrine cells and neurons, being stored together with many different peptide hormones and neuropeptides.
W B, Huttner, H H, Gerdes, P, Rosa
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Chromogranin A and neuroendocrine tumors
Endocrinología y Nutrición (English Edition), 2013Chromogranin A (CgA) is the most abundant granin in gastroenteropancreatic neuroendocrine tumors (GEP-NETs). As a tumor marker is moderately sensitive and nonspecific. Despite the limitations of testing methods, which require careful interpretation, especially in the case of gastrinomas, patients treated with somatostatin analogues, and poorly ...
José Ángel, Díaz Pérez +1 more
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Chromogranin peptides in Alzheimer's disease
Experimental Gerontology, 2004Synaptic disturbances may play a key role in the pathophysiology of Alzheimer's disease. To characterize differential synaptic alterations in the brains of Alzheimer patients, chromogranin A, chromogranin B and secretoneurin were applied as soluble constituents for large dense core vesicles, synaptophysin as a vesicle membrane marker and calbindin as a
Theresa, Lechner +9 more
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Chromogranins as substrate for transglutaminase
Biochemical Pharmacology, 1971Abstract The possible attachment of amines to proteins obtained from adrenal medulla was investigated using transglutaminase as the enzyme. Transglutaminase catalyzes a replacement of the amide group of certain protein-bound glutamine residues by primary amines.
I J, Wajda +3 more
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Increased Fecal Levels of Chromogranin A, Chromogranin B, and Secretoneurin in Collagenous Colitis
Inflammation, 2013Interactions between the enteric nervous system and the immune system are suggested to play an important role in the pathophysiology of inflammatory bowel disease (IBD). This study aims to determine if chromogranin A (CgA), chromogranin B (CgB), and secretoneurin (SN) are detectable in feces (F) from patients with collagenous colitis (CC) and to ...
Michael, Wagner +5 more
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[Chromogranin A, chromogranin B, chromogranin C].
Nihon rinsho. Japanese journal of clinical medicine, 2000K, Takekoshi, T, Nakai, Y, Matsui
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