Results 61 to 70 of about 2,220 (203)

Angiogenic gene signature in human pancreatic cancer correlates with TGF-beta and inflammatory transcriptomes [PDF]

, 2015
Pancreatic ductal adenocarcinomas (PDACs) are hypovascular, but overexpress pro-angiogenic factors and exhibit regions of microvasculature. Using RNA-seq data from The Cancer Genome Atlas (TCGA), we previously reported that ~12% of PDACs have an ...
Craven, Kelly E., Gore, Jesse, Korc, Murray, Wilson, Julie L.   +3 more
core   +2 more sources

Pancreatic Neuroendocrine Tumor Leading to a Diagnosis of Multiple Endocrine Neoplasia Type 1

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Pancreatic neuroendocrine neoplasms are rare but occasionally encountered. They are generally highly vascularized solid tumors, often round in shape with clear boundaries, defined contours, and a homogeneous internal structure. However, they can also present with atypical features, such as cystic degeneration, hemorrhage, calcification, and ...
Noriyuki Hirakawa, Katsuya Kitamura, Kei Yamamoto, Kenichi Tadokoro, Yasunosuke Akita, Jun Uemura, Fumito Yamanishi, Masakazu Abe, Munehide Nakatsugawa, Takao Itoi   +9 more
wiley   +1 more source

Barrett's Esophageal Adenocarcinoma with Neuroendocrine Cell Carcinoma Treated by Endoscopic Submucosal Dissection: A Case Report and Literature Review

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Barrett's esophageal adenocarcinoma (BEA) with neuroendocrine cell carcinoma (NEC) is a rare disease with a poor prognosis. We report a case of BEA with NEC treated by endoscopic submucosal dissection (ESD) with en bloc resection and long‐term survival was achieved without additional treatment.
Yo Kubota, Kenji Ishido, Kusutaro Doi, Gen Kitahara, Takuya Wada, Akinori Watanabe, Hisatomo Ikehara, Chika Kusano   +7 more
wiley   +1 more source

Amylase release from streptolysin O-permeabilized pancreatic acinar cells. Effects of Ca2+, guanosine 5'-[gamma-thio]triphosphate, cyclic AMP, tetanus toxin and botulinum A toxin [PDF]

, 1992
The molecular requirements for amylase release and the intracellular effects of botulinum A toxin and tetanus toxin on amylase release were investigated using rat pancreatic acinar cells permeabilized with streptolysin O.
Ahnert-Hilger, G., Gratzl, Manfred, Kemmer, T. P., Stecher, B., Weller, U.   +4 more
core  

A Case of Pancreatic Neuroendocrine Tumor Growing Intraductal Extension toward the Main Pancreatic Duct Complicated by Thrombocytopenia: Diagnostic Challenges and Management Strategy

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT We present a rare and diagnostically challenging case of a pancreatic neuroendocrine tumor (pNET) with intraductal growth into the main pancreatic duct (MPD), complicated by severe thrombocytopenia due to myelodysplastic syndrome. A 37‐year‐old male presented with thrombocytopenia.
Koichi Soga, Kazuma Sakakibara, Yuki Soma, Manayu Shiina, Mayumi Yamaguchi, Masaru Kuwada, Ryosaku Shirahashi, Ikuhiro Kobori, Shinichi Ban, Masaya Tamano   +9 more
wiley   +1 more source

Small Intestinal Metastasis From Pulmonary Large Cell Carcinoma Detected by Capsule Endoscopy and Balloon‐assisted Endoscopy, Followed by Early Surgical Resection: A Case Report

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Metastasis of lung cancer to the small intestine is rare and often diagnosed only after life‐threatening complications such as perforation or obstruction. We report a case of small intestinal metastasis from pulmonary large cell carcinoma, diagnosed using balloon‐assisted endoscopy (BAE) performed for obscure gastrointestinal bleeding (OGIB ...
Yoshihiro Yokota, Masashi Ohno, Takayuki Imai, Atsushi Nishida, Takuya Shiratori, Eri Tanaka, Toru Miyake, Masaji Tani, Ryoji Kushima, Takuji Iwashita   +9 more
wiley   +1 more source

Forward‐Viewing Endoscopic Ultrasound‐Guided Fine‐Needle Biopsy for a Hypopharyngeal Carcinoma Mimicking a Subepithelial Lesion: A Case Report

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Subepithelial lesions (SELs) of the head and neck have a low diagnostic yield with mucosal biopsy and carry a bleeding risk. Among endoscopic ultrasound–tissue acquisition (EUS‐TA) techniques, fine‐needle biopsy (FNB) provides higher specimen adequacy and diagnostic accuracy than fine‐needle aspiration (FNA).
Kakeru Otomo, Tadayuki Takagi, Jun Wada, Natsuki Ishizaki, Kana Tamazawa, Kohei Suzuki, Masato Aizawa, Hiroshi Ogawa, Osamu Suzuki, Kazutomo Togashi   +9 more
wiley   +1 more source

Immunoglobulin G4‐Related Disease‐Like Gastric Lesion Presenting as Submucosal Tumor‐Like Lesions

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Immunoglobulin G4 (IgG4)‐related disease (RD) is a systemic fibroinflammatory condition characterized by infiltration of IgG4‐positive plasma cells (PCs). Gastrointestinal involvement may present as submucosal tumor–like lesions and poses diagnostic challenges.
Takayasu Kuroda, Kazuya Miyaguchi, Yoshikazu Tsuzuki, Hiroshi Yamaguchi, Hiroyuki Imaeda   +4 more
wiley   +1 more source

Glucagon Secreting Tumors and Glucagonoma Syndrome [PDF]

, 2017
Glucagonomas are the functioning neuroendocrine tumors. These arise from pancreatic islet α-cells. These tumors are extremely rare and have an annual incidence of 1 per 20-40 million population 80% of glucagon-expressing tumors are sporadic, and 20% are ...
Bano, G, Beharry, N, Du Parc, J, Khalid, Y, Mudan, S, Ozair, F   +5 more
core  

A Case of Gastric Neuroendocrine Tumor With a Raspberry‐Like Appearance on the Background of Acid‐Suppressive Therapy‐Related Gastropathy

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT We report the case of a 52‐year old man who was referred to our institution after a routine health check identified an asymptomatic gastric polyp. The medical history of the patient included reflux esophagitis, for which he had been treated with vonoprazan 10 mg daily for 6 years after initially receiving proton pump inhibitors.
Yoshiaki Moriguchi, Jun Nakahodo, Mari Iseki, Toshihiro Funabiki, Yasuhiro Oka, Eriko Noma, Takeo Arakawa, Shin‐ichiro Horiguchi, Osamu Goto, Toshiro Iizuka   +9 more
wiley   +1 more source