Results 111 to 120 of about 946 (139)

Deciphering Atypical Signals Present in Fluorescent In Situ Hybridization Assays in the Diagnosis of Soft Tissue Sarcomas. [PDF]

Cureus
Papakosta AB, Mahaira LG, Dimitriadis ES, Rizou HN, Kyriazoglou AI, Stefanaki K, Papadakis V, Kattamis A, Anthouli FA.   +8 more
europepmc   +1 more source

Atypical B-Cell Acute Lymphoblastic Leukemia with iAMP21 in the Context of Constitutional Ring Chromosome 21: A Case Report and Review of the Genetic Insights. [PDF]

Int J Mol Sci
Gil JV, Avetisyan G, de Las Heras S, Miralles A, Del Cañizo M, Rico Á, Valerio ME, Díaz V, Piñero P, Orellana C, Cervera J, Fuentes C, Fernández JM, Barragán E, Such E, Llop M.   +15 more
europepmc   +1 more source

Exploring the Potential of Optical Genome Mapping in the Diagnosis and Prognosis of Soft Tissue and Bone Tumors. [PDF]

Int J Mol Sci
Berenguer-Rubio A, Such E, Hernández NT, González-Rojo P, Díaz-González Á, Avetisyan G, Gil-Aparicio C, González-López J, Pantoja-Borja N, Rubio-Martínez LA, Hernández-Girón S, Valera-Cuesta MS, Ramírez-Fuentes C, Simonet-Redondo M, Díaz-Beveridge R, de la Calva C, Amaya-Valero JV, Ballester-Ibáñez C, Liquori A, Giner F, Mayordomo-Aranda E.   +20 more
europepmc   +1 more source

Masters of Gene Expression: Transcription Factors in Pediatric Cancers. [PDF]

Cancers (Basel)
Pathania AS.
europepmc   +1 more source

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Abstract 680: Topoisomerase 2 beta facilitates chromatin reorganization during Androgen Receptor induced transcription and contributes to chromoplexy in prostate cancer

Cancer Research, 2022
Abstract Prostate cancer (PCa) is the most common malignancy and second leading cause of cancer death in American men. Androgen Receptor (AR) mediated transcriptional program is central to normal prostate homeostasis and drives PCa growth and survival.
Minh-Tam N. Pham, Michael C. Haffner, Heather C. Wick, Jonathan B. Coulter, Anuj Gupta, Roshan V. Chikarmane, Harshath Gupta, Sarah Wheelan, William G. Nelson, Srinivasan Yegnasubramanian   +9 more
exaly   +3 more sources

Chromoplexy

Methods in Molecular Biology
Chromoplexy is a massive and complex rearrangement mechanism, occurring during a single cell event and characterized by the formation of chain rearrangements affecting multiple chromosomes. This can lead to the formation of fusion genes and the simultaneous disruption of several genes. Chromoplexy was first identified in prostate cancers, but it is now
Vincent Gatinois
exaly   +4 more sources

Abstract 6105: Unravelling the mechanistic basis of chromoplexy, a mutational process driving early cancer genome evolution

Cancer Research, 2023
Abstract Genome evolution can happen gradually or via bursts of rearrangements. Chromoplexy is an example of a process driving rapid genome evolution. This mutational signature is detected in ~18% of human cancers (PCAWG Consortium, 2020) and is frequently observed in prostate adenocarcinoma, lymphoid malignancies, and thyroid ...
Nataliia Serbyn, Myrthe M. Smit, Vimathi S. Gummalla, Gregory J. Brunette, David S. Pellman   +4 more
openaire   +2 more sources

Chromoplexy and FNDC3B::RARB fusion: deciphering a rare case of PML::RARA-negative APL

Blood
Audrey Bidet, Emilie Klein
openaire   +3 more sources

Chromoanagenesis in Multiple Myeloma: A Comprehensive Overview

Methods in Molecular Biology
Agnes Daudignon, Hélène Guermouche
exaly   +2 more sources

ISCN and Chromoanagenesis

Methods in Molecular Biology
Caroline Schluth-Bolard, Jean-Michel Dupont   +1 more
exaly   +2 more sources