Results 1 to 10 of about 1,000,594 (265)
Targeting chromosome trisomy for chromosome editing [PDF]
Scientific Reports, 2021 AbstractA trisomy is a type of aneuploidy characterised by an additional chromosome. The additional chromosome theoretically accepts any kind of changes since it is not necessary for cellular proliferation. This advantage led us to apply two chromosome manipulation methods to autosomal trisomy in chicken DT40 cells.
Kouji Hirota +3 more
openaire +4 more sources
Chromosomes, chromosome anomalies [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Educational Items on Chromosomes, chromosome anomalies.
Huret, JL, Leonard, C, Savage, JRK
openaire +3 more sources
Chromosome Painting of Mouse Chromosomes [PDF]
, 2018 Chromosome painting enables the visualization of chromosomes and has been used extensively in cytogenetics. Chromosome paint probes, which consist of a pooled composite of DNA-FISH probes, bind to nonrepetitive sequences for individual chromosomes [1, 2].
Hua, Lisa L, Mikawa, Takashi
openaire +4 more sources
Cell, 2002 In RNA-mediated interference (RNAi), double-stranded RNAs (dsRNAs) target complementary mRNAs for degradation. New work demonstrates that essential chromosomal functions are mediated through RNAi protein components and short RNAs, which alter chromosome function at specific DNA loci via histone modification.
Abby F. Dernburg, Gary H. Karpen
openaire +2 more sources
PLOS Genetics, 2020 Holocentric chromosomes possess multiple kinetochores along their length rather than the single centromere typical of other chromosomes [1]. They have been described for the first time in cytogenetic experiments dating from 1935 and, since this first observation, the term holocentric chromosome has referred to chromosomes that: i.
Mauro Mandrioli, Gian Carlo Manicardi
openaire +6 more sources
Molecular cytotaxonomy of primates by chromosomal in situ suppression hybridization [PDF]
, 1990 A new strategy for analyzing chromosomal evolution in primates is presented using chromosomal in situ suppression (CISS) hybridization. Biotin-labeled DNA libraries from flow-sorted human chromosomes are hybridized to chromosome preparations of ...
Anna Jauch +22 more
core +1 more source
Architecture of metaphase chromosomes and chromosome scaffolds. [PDF]
The Journal of cell biology, 1983 We have developed procedures for depositing intact mitotic chromosomes and isolated residual scaffolds on electron microscope grids at controlled and reproducible levels of compaction. The chromosomes were isolated using a recently developed aqueous method. Our study has addressed two different aspects of chromosome structure.
Earnshaw, William C. +1 more
openaire +4 more sources
Experimental Cell Research, 2020 International ...
Fachinetti, Daniele +2 more
openaire +4 more sources
The effect of HIV and antiretroviral therapy on chromosomal radiosensitivity [PDF]
, 2015 Introduction: Antiretroviral Treatment (ART) has led to an improvement in survival of HIV infected individuals. Some of them will develop cancer during the course of their infection and will require radiation therapy.
Baeyens, Ans +3 more
core +1 more source
Chromosomal rearrangements in cattle and pigs revealed by chromosome microdissection and chromosome painting [PDF]
Genetics Selection Evolution, 2003 A pericentric inversion of chromosome 4 in a boar, as well as a case of (2q-;5p+) translocation mosaicism in a bull were analysed by chromosome painting using probes generated by conventional microdissection. For the porcine inversion, probes specific for p arms and q arms were produced and hybridised simultaneously on metaphases of a heterozygote ...
Pinton, Alain +2 more
openaire +10 more sources