Results 31 to 40 of about 476,312 (268)

Reactions of Triticum urartu accessions to two races of the wheat yellow rust pathogen

Crop Journal, 2018
Triticum urartu (AA, 2n = 2x = 14), a wild grass endemic to the Fertile Crescent (FC), is the progenitor of the A subgenome in common wheat. It belongs to the primary gene pool for wheat improvement. Here, we evaluated the yellow rust (caused by Puccinia
Jibin Xiao, Lingli Dong, Huaibing Jin, Juncheng Zhang, Kunpu Zhang, Na Liu, Xinyun Han, Hongyuan Zheng, Wenming Zheng, Daowen Wang   +9 more
doaj   +1 more source

Y-Chromosome Microdeletions: A Review of Prevalence, Screening, and Clinical Considerations

The Application of Clinical Genetics, 2021
Matthew J Rabinowitz, Phillip J Huffman, Nora M Haney, Taylor P Kohn The James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USACorrespondence: Taylor P KohnJames Buchanan Brady Urological Institute ...
Rabinowitz MJ, Huffman PJ, Haney NM, Kohn TP   +3 more
doaj  

A Novel Chromosomal Translocation Identified due to Complex Genetic Instability in iPSC Generated for Choroideremia

Cells, 2019
Induced pluripotent stem cells (iPSCs) have revolutionized the study of human diseases as they can renew indefinitely, undergo multi-lineage differentiation, and generate disease-specific models. However, the difficulty of working with iPSCs is that they
Nejla Erkilic, Vincent Gatinois, Simona Torriano, Pauline Bouret, Carla Sanjurjo-Soriano, Valerie De Luca, Krishna Damodar, Nicolas Cereso, Jacques Puechberty, Rocio Sanchez-Alcudia, Christian P. Hamel, Carmen Ayuso, Isabelle Meunier, Franck Pellestor, Vasiliki Kalatzis   +14 more
doaj   +1 more source

Architecture of metaphase chromosomes and chromosome scaffolds. [PDF]

The Journal of cell biology, 1983
We have developed procedures for depositing intact mitotic chromosomes and isolated residual scaffolds on electron microscope grids at controlled and reproducible levels of compaction. The chromosomes were isolated using a recently developed aqueous method. Our study has addressed two different aspects of chromosome structure.
Earnshaw, William C., Laemmli, Ulrich Karl   +1 more
openaire   +3 more sources

Clinical significance of chromosomal integrity in gastric cancers

The International Journal of Biological Markers, 2022
Background A whole-exome or targeted cancer genes panel by next-generation sequencing has been used widely in assisting individualized treatment decisions. Currently, multiple algorithms are developed to estimate DNA copy numbers based on sequencing data,
Rukui Zhang, Zhaorui Liu, Xusheng Chang, Yuan Gao, Huan Han, Xiaona Liu, Hui Cai, Qiqing Fu, Lei Liu, Kai Yin   +9 more
doaj   +1 more source

Antenatal screening for chromosomal and genetic abnormalities:Cost effectiveness and outcome [PDF]

Journal of Analytical Research in Clinical Medicine, 2018
Introduction: As an essential part of antenatal care, pregnant women of all ages should be offered screening for chromosomal abnormalities before 20 weeks of gestation.
Simin Tagavi, Hossein Alikhah, Sharareh Barband, Fereshteh Farhadi, Mohammad Naghavi-Behzad, Saeed Jodi-Khajeh, Sahar Mohammadi, Reza Piri   +7 more
doaj   +1 more source

Optical genome mapping for detection of chromosomal aberrations in prenatal diagnosis

Acta Obstetricia et Gynecologica Scandinavica, 2023
Introduction Chromosomal aberrations are the most important etiological factors for birth defects. Optical genome mapping is a novel cytogenetic tool for detecting a broad range of chromosomal aberrations in a single assay, but relevant clinical ...
Qinxin Zhang, Yan Wang, Yiyun Xu, Ran Zhou, Mingtao Huang, Fengchang Qiao, Lulu Meng, An Liu, Jing Zhou, Li Li, Xiuqing Ji, Zhengfeng Xu, Ping Hu   +12 more
doaj   +1 more source

Cytogenetic Analysis for Suspected Chromosomal Abnormalities; A Five Years Experience [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Chromosomal abnormalities are the results of alterations in the number or structure of chromosomes causing significant human morbidity and mortality.
Sunil Kumar Polipalli, Vijay Kumar Karra, Ankur Jindal, Madhavi Puppala, Pratiksha Singh, Kanchan Rawat, Seema Kapoor   +6 more
doaj   +1 more source

Effectiveness of non-invasive chromosomal screening for normal karyotype and chromosomal rearrangements

Frontiers in Genetics, 2023
PurposeTo study the accuracy of non-invasive chromosomal screening (NICS) results, in normal chromosomes and chromosomal rearrangement groups and to investigate whether using trophoblast cell biopsy along with NICS, to choose embryos for transfer can ...
Bo-lan Sun, Yong Wang, Sixi-Wen, Liang Zhou, Chun-hui Zhang, Ze-Xuan Wu, Jie Qiao, Qing-yuan Sun, Ya-xin Yao, Jing Wang, Zi-Yun Yi, Wei-Ping Qian   +11 more
doaj   +1 more source

Chromosomal instability in Streptomyces avermitilis: major deletion in the central region and stable circularized chromosome

BMC Microbiology, 2010
Background The chromosome of Streptomyces has been shown to be unstable, frequently undergoing gross chromosomal rearrangements. However, the mechanisms underlying this phenomenon remain unclear, with previous studies focused on two chromosomal ends as ...
Wen Ying, Chen Zhi, Zhang Xiaojuan, He Fei, Chen Wei, Li Jilun   +5 more
doaj   +1 more source