Results 11 to 20 of about 1,274,518 (371)

Targeting chromosome trisomy for chromosome editing [PDF]

open access: yesScientific Reports, 2021
AbstractA trisomy is a type of aneuploidy characterised by an additional chromosome. The additional chromosome theoretically accepts any kind of changes since it is not necessary for cellular proliferation. This advantage led us to apply two chromosome manipulation methods to autosomal trisomy in chicken DT40 cells.
Kouji Hirota   +3 more
openaire   +4 more sources

Chromosomes, chromosome anomalies [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Educational Items on Chromosomes, chromosome anomalies.
Huret, JL, Leonard, C, Savage, JRK
openaire   +3 more sources

Chromosome Painting of Mouse Chromosomes [PDF]

open access: yes, 2018
Chromosome painting enables the visualization of chromosomes and has been used extensively in cytogenetics. Chromosome paint probes, which consist of a pooled composite of DNA-FISH probes, bind to nonrepetitive sequences for individual chromosomes [1, 2].
Hua, Lisa L, Mikawa, Takashi
openaire   +3 more sources

A Chromosome RNAissance [PDF]

open access: yesCell, 2002
In RNA-mediated interference (RNAi), double-stranded RNAs (dsRNAs) target complementary mRNAs for degradation. New work demonstrates that essential chromosomal functions are mediated through RNAi protein components and short RNAs, which alter chromosome function at specific DNA loci via histone modification.
Abby F. Dernburg, Gary H. Karpen
openaire   +2 more sources

Holocentric chromosomes

open access: yesPLOS Genetics, 2020
Holocentric chromosomes possess multiple kinetochores along their length rather than the single centromere typical of other chromosomes [1]. They have been described for the first time in cytogenetic experiments dating from 1935 and, since this first observation, the term holocentric chromosome has referred to chromosomes that: i.
Mauro Mandrioli, Gian Carlo Manicardi
openaire   +6 more sources

Chromosomal rearrangements in cattle and pigs revealed by chromosome microdissection and chromosome painting [PDF]

open access: yesGenetics Selection Evolution, 2003
A pericentric inversion of chromosome 4 in a boar, as well as a case of (2q-;5p+) translocation mosaicism in a bull were analysed by chromosome painting using probes generated by conventional microdissection. For the porcine inversion, probes specific for p arms and q arms were produced and hybridised simultaneously on metaphases of a heterozygote ...
Pinton, Alain   +2 more
openaire   +10 more sources

Architecture of metaphase chromosomes and chromosome scaffolds. [PDF]

open access: yesThe Journal of cell biology, 1983
We have developed procedures for depositing intact mitotic chromosomes and isolated residual scaffolds on electron microscope grids at controlled and reproducible levels of compaction. The chromosomes were isolated using a recently developed aqueous method. Our study has addressed two different aspects of chromosome structure.
Earnshaw, William C.   +1 more
openaire   +4 more sources

Artificial chromosomes [PDF]

open access: yesExperimental Cell Research, 2020
International ...
Fachinetti, Daniele   +2 more
openaire   +4 more sources

Editöre Mektup - Noncompaction on scleroderma

open access: yesTürk Kardiyoloji Derneği Arşivi, 2016
The abstract of the article is in the Full ...
Sinda Zarrouk Mahjoub, Josef Finsterer
doaj   +1 more source

Chromosomal instability drives metastasis through a cytosolic DNA response

open access: yesNature, 2017
Chromosomal instability is a hallmark of cancer that results from ongoing errors in chromosome segregation during mitosis. Although chromosomal instability is a major driver of tumour evolution, its role in metastasis has not been established.
S. Bakhoum   +32 more
semanticscholar   +1 more source

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