Results 41 to 50 of about 1,277,656 (371)

A Mechanism Linking Extra Centrosomes to Chromosomal Instability

open access: yesNature, 2009
Chromosomal instability (CIN) is a hallmark of many tumours and correlates with the presence of extra centrosomes. However, a direct mechanistic link between extra centrosomes and CIN has not been established.
Neil J. Ganem, S. Godinho, D. Pellman
semanticscholar   +1 more source

Trends in Karyotype Evolution in Astyanax (Teleostei, Characiformes, Characidae): Insights From Molecular Data

open access: yesFrontiers in Genetics, 2018
The study of patterns and evolutionary processes in neotropical fish is not always an easy task due the wide distribution of major fish groups in large and extensive river basins. Thus, it is not always possible to detect or correlate possible effects of
Rubens Pazza   +2 more
doaj   +1 more source

The chromosomes of the Filariae [PDF]

open access: yesFilaria Journal, 2005
An understanding of the nature of the chromosomes of the filariae is expected to greatly assist the future interpretation of genome data. Filarial development is not eutelic, and there does not seem to be a fixed number of cell divisions in the way that there is in Caenorhabditis.
Rory J. Post, Rory J. Post
openaire   +3 more sources

Chromosomal microarray versus karyotyping for prenatal diagnosis.

open access: yesNew England Journal of Medicine, 2012
BACKGROUND Chromosomal microarray analysis has emerged as a primary diagnostic tool for the evaluation of developmental delay and structural malformations in children.
R. Wapner   +23 more
semanticscholar   +1 more source

Chromosomal deletions detected at amniocentesis

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2014
Objective: The aim of this study is to present the incidence, prenatal and postnatal findings, and modes of ascertainment in chromosomal deletions detected at amniocentesis.
Chen-Ju Lin   +10 more
doaj   +1 more source

Chromosome Oscillations in Mitosis [PDF]

open access: yes, 2005
Successful cell division requires a tight regulation of chromosome motion via the activity of molecular motors. Many of the key players at the origin of the forces generating the movement have been identified, but their spatial and temporal organization remains elusive.
arxiv   +1 more source

Role of the Number of Microtubules in Chromosome Segregation during Cell Division [PDF]

open access: yesPLoS ONE 10(10): e0141305 (2015), 2015
Faithful segregation of genetic material during cell division requires alignment of chromosomes between two spindle poles and attachment of their kinetochores to each of the poles. Failure of these complex dynamical processes leads to chromosomal instability (CIN), a characteristic feature of several diseases including cancer.
arxiv   +1 more source

The chromosomal organization of horizontal gene transfer in bacteria

open access: yesNature Communications, 2017
Bacterial adaptation is accelerated by the acquisition of novel traits through horizontal gene transfer, but the integration of these genes affects genome organization.
P. Oliveira   +3 more
semanticscholar   +1 more source

Chromosomal Speciation Revisited: Modes of Diversification in Australian Morabine Grasshoppers (Vandiemenella, viatica Species Group)

open access: yesInsects, 2011
Chromosomal rearrangements can alter the rate and patterns of gene flow within or between species through a reduction in the fitness of chromosomal hybrids or by reducing recombination rates in rearranged areas of the genome.
Steven J. B. Cooper   +2 more
doaj   +1 more source

Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis

open access: yesAging and Cancer, Volume 3, Issue 3-4, Page 133-146, September-December 2022., 2022
One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen   +3 more
wiley   +1 more source

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