Results 41 to 50 of about 859,918 (327)

The genotoxicity of an aqueous extract of Gyejibokryeong-hwan

open access: yesBMC Complementary and Alternative Medicine, 2018
Background Gyejibokryeong-hwan (Guizhi Fuling Wan in China), a mixture of five herbal plants, is a well-known treatment for renal diseases including those associated with climacteric syndrome.
Mee-Young Lee   +5 more
doaj   +1 more source

The Effects of Zinc Phosphide and Brodifacoum on Mitotic Index and Chromosomal Aberrations in Germ Cells of Wild type and Laboratory Mice (Mus Musculus) [PDF]

open access: yesEngineering and Technology Journal, 2014
The genotoxic effects of two wildy used rodenticides in Iraq (Zinc phosphide and Brodifacoum) were studied in wildtype and Balbc mice,by using mitotic index(MI) and chromosomal aberration (CA).
Abbas Abdullah Mohammed, Smail K.Subber
doaj   +1 more source

Effect of custom aberration filter.

open access: yes, 2013
Visualization of chromosomal alterations on chromosome 1 in Genomic Workbench using aberration detection algorithm ADM-2. Blue filled areas denote a gain (right) or loss (left) of chromosomal material.
Bianca Behrens (426600)   +6 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Genotoxicity test of eight natural color additives in the Korean market

open access: yesGenes and Environment, 2022
Background Various natural color additives are preferred by many consumers over synthetic color additives because they are perceived to be safer. However, most do not have sufficient toxicity data for safety assurance.
Byungkyung Do, Hoonjeong Kwon
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Deletion 6q as a recurrent chromosomal aberration in T-cell large granular lymphocyte leukemia

open access: yes, 2002
T-cell large granular lymphocyte (T-LGL) leukemia is an uncommon disease, with limited information on karyotypic aberrations. No consistent chromosomal changes have thus far been described.
Kwong, YL, Pang, A, Au, WY, Man, C
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Study on In Vitro Chromosome Aberration Test for Nanomaterials and Medical Devices Containing Nanomaterials

open access: yesZhongguo yiliao qixie zazhi
ObjectiveTo preliminarily explore a genotoxicity test system suitable for evaluating the risk of chromosomal damage in nanomaterials and medical devices containing nanomaterials. MethodsPolystyrene nanospheres were used as nanoscale negative controls (20
Hui WU   +5 more
doaj   +1 more source

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