Optical genome mapping for detection of chromosomal aberrations in prenatal diagnosis [PDF]
Acta Obstetricia et Gynecologica Scandinavica, 2023 Introduction Chromosomal aberrations are the most important etiological factors for birth defects. Optical genome mapping is a novel cytogenetic tool for detecting a broad range of chromosomal aberrations in a single assay, but relevant clinical ...
Qinxin Zhang +12 more
doaj +2 more sources
Chromosomal Aberrations and Oxidative Stress in Psoriatic Patients with and without Metabolic Syndrome [PDF]
Metabolites, 2022 Psoriasis and metabolic syndrome (MetS), a common comorbidity of psoriasis, are associated with mild chronic systemic inflammation that increases oxidative stress and causes cell and tissue damage.
Drahomira Holmannova +9 more
doaj +2 more sources
Quantification of Chromosomal Aberrations in Mammalian Cells [PDF]
Bio-Protocol, 2023 Maintenance of genome integrity requires efficient and faithful resolution of DNA breaks and DNA replication obstacles. Dysfunctions in any of the processes orchestrating such resolution can lead to chromosomal instability, which appears as numerical and
Inés Paniagua, Jacqueline Jacobs
doaj +2 more sources
Chromosomal aberrations and prognostic analysis of secondary acute myeloid leukemia—a retrospective study [PDF]
PeerJ, 2023 Background Secondary acute myeloid leukemia (S-AML) patients generally have a poor prognosis, but the chromosomal aberrations of S-AML have been rarely reported. We aimed to explore the chromosomal aberrations and clinical significance in patients with S-
Mingzhu Song +6 more
doaj +3 more sources
HPV type-related chromosomal profiles in high-grade cervical intraepithelial neoplasia [PDF]
BMC Cancer, 2012 Background The development of cervical cancer and its high-grade precursor lesions (Cervical Intraepithelial Neoplasia grade 2/3 [CIN2/3]) result from a persistent infection with high-risk human papillomavirus (hrHPV) types and the accumulation of (epi ...
Bierkens Mariska +7 more
doaj +6 more sources
Galician Medical Journal, 2017 The frequency and spectrum of chromosomal aberrations, acrocentric chromosome associations among 264 long livers with arterial hypertension and osteoarthritis residing in the Carpathian region were analyzed.
Ruslan Kozoviy
doaj +3 more sources
Chromosomal aberrations after induced pluripotent stem cells reprogramming [PDF]
Genetics and Molecular Biology, 2021 Induced pluripotent stem cells (iPSCs) are generated from adult cells that have been reprogrammed to pluripotency. However, in vitro cultivation and genetic reprogramming increase genetic instability, which could result in chromosomal abnormalities ...
Isadora May Vaz +9 more
doaj +2 more sources
Shanghai yufang yixue, 2023 ObjectiveTo investigate the current status and high-risk factors of chromosomal aberrations in peripheral blood lymphocytes （PBL） of radiation workers in Hainan Province.MethodsA total of 200 radiological workers who underwent occupational health ...
ZHANG Yuhong +5 more
doaj +1 more source
Efficacy of prenatal diagnostic in mothers of children with chromosomal aberrations diagnosed postnatally [PDF]
РМЖ. Мать и дитя, 2021 Yu.A. Dudareva1, A.A. Shipilov2 1Altay State Medical University, Barnaul, Russian Federation 2Altay Regional Clinical Perinatal Center, Barnaul, Russian Federation Aim: to assess the efficacy of prenatal screening in women those children were ...
Yu.A. Dudareva, A.A. Shipilov
doaj +2 more sources
EFFECT OF GRADEN CRESS (Lepidium sativum) ON CHROMOSOMAL ABERRATIONS AND ITS ANTI - EFFECT ON INDUCTION OF CHROMOSOMAL ABERRATIONS IN WHITE MICE BONE MARROW CELLS USING SHORT – TERM TESTS [PDF]
Mesopotamia Journal of Agriculture, 2009 Effect of garden cress Lepidium sativum (a cruciferous plant) on induction of chromosomal aberrations in bone marrow cells of white mice was studied , in addition to its effect to reverse the chromosomal aberrations induced by drug cyclophosphamide (Cp).
Ilham A. Khalaf
doaj +1 more source