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Chromosomal Aberrations in Cattle. [PDF]
Genes (Basel), 2021 Chromosomal aberrations and their mechanisms have been studied for many years in livestock. In cattle, chromosomal abnormalities are often associated with serious reproduction-related problems, such as infertility of carriers and early mortality of ...
Holečková B +7 more
europepmc +2 more sources
Optical genome mapping for detection of chromosomal aberrations in prenatal diagnosis [PDF]
Acta Obstetricia et Gynecologica Scandinavica, 2023 Introduction Chromosomal aberrations are the most important etiological factors for birth defects. Optical genome mapping is a novel cytogenetic tool for detecting a broad range of chromosomal aberrations in a single assay, but relevant clinical ...
Qinxin Zhang +12 more
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Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq
Nature Communications, 2016 Chromosomal aberrations can be detected by global gene expression analysis. Here, the authors report eSNP-Karyotyping, a new method that can detect chromosomal aberrations by measuring the ratio of expression between the two alleles without comparison to
Uri Weissbein +3 more
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Chromosomal Aberrations and Oxidative Stress in Psoriatic Patients with and without Metabolic Syndrome [PDF]
Metabolites, 2022 Psoriasis and metabolic syndrome (MetS), a common comorbidity of psoriasis, are associated with mild chronic systemic inflammation that increases oxidative stress and causes cell and tissue damage.
Drahomira Holmannova +9 more
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Quantification of Chromosomal Aberrations in Mammalian Cells [PDF]
Bio-Protocol, 2023 Maintenance of genome integrity requires efficient and faithful resolution of DNA breaks and DNA replication obstacles. Dysfunctions in any of the processes orchestrating such resolution can lead to chromosomal instability, which appears as numerical and
Inés Paniagua, Jacqueline Jacobs
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Chromosomal aberrations and prognostic analysis of secondary acute myeloid leukemia—a retrospective study [PDF]
PeerJ, 2023 Background Secondary acute myeloid leukemia (S-AML) patients generally have a poor prognosis, but the chromosomal aberrations of S-AML have been rarely reported. We aimed to explore the chromosomal aberrations and clinical significance in patients with S-
Mingzhu Song +6 more
doaj +3 more sources
Haematologica, 2010 Background Additional chromosomal aberrations in Philadelphia chromosome-positive chronic myeloid leukemia are non-random and strongly associated with disease progression, but their prognostic impact and effect on treatment response is not clear.
Theo D. Kim +8 more
doaj +2 more sources
Galician Medical Journal, 2017 The frequency and spectrum of chromosomal aberrations, acrocentric chromosome associations among 264 long livers with arterial hypertension and osteoarthritis residing in the Carpathian region were analyzed.
Ruslan Kozoviy
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Chromosomal aberrations after induced pluripotent stem cells reprogramming [PDF]
Genetics and Molecular Biology, 2021 Induced pluripotent stem cells (iPSCs) are generated from adult cells that have been reprogrammed to pluripotency. However, in vitro cultivation and genetic reprogramming increase genetic instability, which could result in chromosomal abnormalities ...
Isadora May Vaz +9 more
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GeneBreak: detection of recurrent DNA copy number aberration-associated chromosomal breakpoints within genes [version 2; referees: 2 approved] [PDF]
F1000Research, 2017 Development of cancer is driven by somatic alterations, including numerical and structural chromosomal aberrations. Currently, several computational methods are available and are widely applied to detect numerical copy number aberrations (CNAs) of ...
Evert van den Broek +7 more
doaj +2 more sources