Results 41 to 50 of about 66,699 (303)
Chromosomal aberrations after induced pluripotent stem cells reprogramming. [PDF]
Genet Mol Biol, 2021 Induced pluripotent stem cells (iPSCs) are generated from adult cells that have been reprogrammed to pluripotency. However, in vitro cultivation and genetic reprogramming increase genetic instability, which could result in chromosomal abnormalities ...
Vaz IM +9 more
europepmc +2 more sources
Radiation-induced chromosomal aberrations in grape Phylloxera
Advances in Horticultural Science, 2013 Chromosomal aberrations in phylloxera females induced by different doses of gamma irradiation were detected. The results showed that the chromosomes of all tested embryos of irradiated phylloxera had aberrations, regardless of dose.
H. Makee, N. Tafesh, I. Idris
doaj +1 more source
Identify latent chromosomal aberrations relevant to myelodysplastic syndromes [PDF]
, 2017 Myelodysplastic syndromes (MDS) are a group of heterogeneous hematologic malignancies. This study aims to identify latent chromosomal abnormalities relevant to MDS, which may optimize the current diagnosis of MDS.
Weihong Yang +6 more
core +1 more source
Correlation between Cytogenetic Findings and Spermatogenic Failure in Bulgarian Infertile Men
Life, 2022 The aim of our study was to determine the type and frequency of chromosomal aberrations and polymorphisms in men with different degrees of spermatogenic failure in comparison to men with normozoospermia, in order to find correlations between cytogenetic ...
Svetlana Yovinska +10 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Survival after relapse in pediatric acute myeloid leukemia (AML) remains poor, highlighting the critical importance of identifying prognostic factors to guide optimal relapse management. Methods We investigated the prognostic impact of multiparameter flow cytometry (MFC) measurable residual disease (MRD) in 188 patients with first ...
Camilla Poulsen +21 more
wiley +1 more source
Higher frequency of chromosomal aberrations in ovarian endometriosis compared to extragonadal endometriosis: A possible link to endometrioid adenocarcinoma [PDF]
, 2006 Endometriosis may progress to invasive endometrioid adenocarcinoma, particularly in the ovary. Up to now, little is known of the molecular mechanisms possibly involved in the malignant transformation of endometriosis.
Burckhardt, Elisabeth +2 more
core +1 more source
Chromosomal Aberrations and Schizophrenia [PDF]
British Journal of Psychiatry, 1992 Chromosomal aberrations associated with schizophrenic disorders may suggest regions in which to focus a search for genes predisposing to schizophrenia by a linkage strategy. As for other genetic illnesses, chromosomal abnormalities may also provide useful tools for subsequent physical mapping, fine localisation, and isolation of important ...
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Childhood aplastic anemia (AA) is a rare disease, and both the disease itself and its treatment cause significant morbidity. We aimed to determine the contemporary incidence of childhood AA in Finland, to compare the clinical characteristics of AA against inherited bone marrow failure syndromes (IBMFS) and refractory cytopenia of ...
Lauri‐Matti Kulmala +8 more
wiley +1 more source
, 2015 Acute leukemia is a worldwide disease with an incidence of approximately 4/100 000 per year; 70% of the cases are acute myeloid leukemia (AML). The salient pathologic feature of AML is the excessive accumulation of immature myeloid blasts in the bone ...
Johansson, Bertil, +2 more
core +1 more source
GENOTOXIC EFFECT OF HOSTATHION IN MICE [PDF]
Veterinary Medical Journal - Giza, 2001 The genotoxic potential of technical hostathion was studied in the in vivo mouse system. The test Parameters used were chromosomal aberrations Assay and mitotic index in bone marrow cells; and Meiotic chromosomal aberrations assay and Meiotic index in ...
K ABDEL AZIZ +3 more
doaj +1 more source