Results 51 to 60 of about 66,699 (303)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Details of CT1258 chromosomal aberrations. [PDF]
, 2014 Detailed presentation of chromosomal aberrations found in metaphases of CT1258, CT1258-EGFP and CT1258-EGFP-HMGA2. Two derivative chromosomes (der(1;5)) and the large bi-armed marker chromosome (mar) were found in each cell line.
Ingo Nolte (50031) +6 more
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Chromosomal aberrations in primary PDGFRA-mutated gastrointestinal stromal tumors [PDF]
, 2014 Approximately 15% of gastrointestinal stromal tumors (GISTs) harbor mutations in the platelet-derived growth factor receptor alpha (PDGFRA) gene. Chromosomal aberrations play a crucial role in tumor progression and correlate with clinical behavior ...
Cameron, Silke +6 more
core +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Brazilian Journal of Medical and Biological Research, 2012 Polymorphisms of the p53 gene, which participates in DNA repair, can affect the functioning of the p53 protein. The Arg and Pro variants in p53 codon 72 were shown to have different regulation properties of p53-dependent DNA repair target genes that can ...
H. Akbaş +6 more
doaj +3 more sources
Induction of chromosome shattering by ultraviolet light and caffeine [PDF]
, 1981 Synchronized and asynchronously growing cells of a V79 sub-line of the Chinese hamster were either partial-cell irradiation (λ, 254 nm) or laser-UV-microirradiated (λ, 257 nm).
Cremer, Thomas +3 more
core +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Detection of Activity-Induced Chromosomal Aberrations Using Image Analysis [PDF]
, 1992 Image analysis was applied to chromosomal aberration tests carried out on Chinese hamster lung cell (CHL). First, chromosomes on pictures which had been judged to be normals or aberrations by experts were analyzed by the authors' image analyzer.
S. Ito, Y. Matsuoka, H. Sumitomo
core +1 more source
Prevalence of chromosomal aberrations on CLL patients detected by FISH. [PDF]
, 2021 Prevalence of chromosomal aberrations on CLL patients detected by FISH.
Adriana Ramos (119717) +4 more
core +1 more source