Results 71 to 80 of about 246,792 (294)
Biological Research, 1999 The effect of the G2 repair of chromosomal damage in lymphocytes from workers exposed to low levels of X- or g-rays was evaluated. Samples of peripheral blood were collected from 15 radiation workers, 20 subjects working in radiodiagnostics, and 30 ...
J PINCHEIRA +6 more
doaj
Chromosomal in situ suppression hybridization of immunologically classified mitotic cells in hematologic malignancies [PDF]
, 1992 Chromosomal in situ suppression (CISS) hybridization was performed with library DNA from sorted human chromosomes 8, 9, 15, 17, 21, and 22 on immunologically stained bone marrow cells of four patients with a hematologic neoplasm, including two patients ...
Knuutila, Sakari +15 more
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FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Induction of chromosomal aberrations and SCE by chloramphenicol
, 1991 The induction of chromosomal aberrations and sister-chromatid exchanges (SCE) was studied in human lymphocyte cultures treated with chloramphenicol (CAP), an antimicrobial agent acting by inhibiting protein synthesis. Moreover chromosomal aberrations and
RAINALDI G +3 more
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Chromosomal Aberrations in a Natural Population of Chironomus Tentans Exposed to Chronic Low-Level Environmental Radiation [PDF]
, 1964 The salivary gland chromosomes of Chironomus tentans larvae collected from White Oak Creek, an area contaminated by radioactive waste from the Oak Ridge National Laboratory, and from six uncontaminated areas were examined for chromosomal aberrations ...
Nelson, D. J. +2 more
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FEBS Open Bio, EarlyView.Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
A role for topoisomerase II alpha in chromosome damage in human cell lines [PDF]
, 2010 Human response to ionising radiation (IR) shows a wide variation. This is most clearly seen in the radiation-response of cells as measured by frequencies of chromosomal aberrations.
Terry, Samantha Y.A.
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Molecular Cytogenetics: Genomic Imbalances in Colorectal Cancer and their Clinical Impact
Cellular Oncology, 2006 Chromosomal aberrations play a dominant role in colorectal carcinogenesis. The application of fluorescence in situ hybridization (FISH) based techniques such as comparative genomic hybridization (CGH) and spectral karyotyping (SKY) revealed that ...
Marian Grade +4 more
doaj +1 more source
Chromosomal aberrations induced in barley by LSD
, 1970 Seeds of hulled barley (Hordeum vulgare) were germinated and then treated with LSD. Preparations of squashed root tips stained with Feulgen revealed extensive chromosomal aberrations, most of which were chromosome breaks.
Jain, H. K., Singh, M. P., Kalia, C. S.
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Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source