Results 91 to 100 of about 246,792 (294)

Research on Spontaneously Emerged Chromosomal Aberrations in the Periphery Blood Lymphocytes in Cattle (‘Buša’ Breed) [PDF]

, 2007
Knowledge of spontaneous aberrations, namely, of their frequency in non-irradiated cells is of paramount importance not only in cytogenetic research, but also in contemporary animal production.
Hamamdžić, Muhidin, Muhidin Hamamdžić, Brka, Muhamed, Mensur Vegara, Dunja Rukavina, Hasanbašić, Danica, Danica Hasanbašić, Aida Hodžić, Vegara, Mensur, Muhamed Brka, Rukavina, Dunja, Hodžić, Aida   +11 more
core   +1 more source

Autoimmune Comorbidities as Modifiers of Phenotypic Heterogeneity in Facioscapulohumeral Dystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral dystrophy type 1 (FSHD1) shows clinical heterogeneity that is only partly explained by D4Z4 repeat unit (RU) size. Although immune and inflammatory mechanisms may contribute to disease variability, the prevalence and clinical impact of autoimmune diseases in FSHD remain unclear.
Jonathan Pini, Giulia Tammam, Andra Ezaru, Manuela Gambella, Benoît Sanson, Luisa Villa, Michele Cavalli, Mihai‐Bogdan Ioncea, Angela Puma, Sabrina Sacconi   +9 more
wiley   +1 more source

Micronuclei versus Chromosomal Aberrations Induced by X-Ray in Radiosensitive Mammalian Cells

Iranian Journal of Public Health, 2015
Background: An experimental study was accomplished to compare estimation methods of ionizing radiations genotoxicity in mammalian cell cultures by means of two cytogenetic parameters with focus on aberrant cells characterized by multiple chromosomal ...
Cristina Plamadeala, Andrzej Wojcik, Dorina Creanga   +2 more
doaj  

Evaluation of anti-genotoxicity of the leaf extracts of Morinda citrifolia Linn.

Plant, Soil and Environment, 2011
Morinda citrifolia Linn. (family Rubiaceae) is a small tree occurring in tropical areas of the world. The plant contains several medicinally active components that exhibit the therapeutic effects such as antibacterial, antiviral and anticancer activities.
S. Sreeranjini, E.A. Siril
doaj   +1 more source

The Distribution of Chromosomal Aberrations in Human Cells Predicted by a Generalized Time-Dependent Model of Radiation-Induced Formation of Aberrations [PDF]

, 2011
New experimental data show how chromosomal aberrations for low- and high-LET radiation are dependent on DSB repair deficiencies in wild-type, AT and NBS cells.
Ponomarev, Artem L., Cucinotta, F. A., George, K.   +2 more
core  

Chromosomal aberrations in Wilms' tumour

, 1997
In 26 consecutive patients operated for Wilms' tumour samples from the tumour were genetically analyzed. Clonal acquired chromosome aberrations were found in 13 patients and a constitutional trisomy 18 as the sole change in 1.
Wiebe, Thomas, Kullendorff, Carl-Magnus, Wiebe, Thomas,, Lund University., Kullendorff, Carl-Magnus,   +4 more
core   +1 more source

Juvenile Huntington Disease With Cerebellar‐Predominant Atrophy Identified by Genome Sequencing

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Juvenile Huntington disease accounts for a small fraction of Huntington disease cases and is driven by the largest trinucleotide repeat expansions. We describe a 6‐year‐old boy with progressive global regression, generalized dystonia, and epilepsy, in whom serial imaging showed striking cerebellar‐predominant atrophy with an initially normal ...
Enrique Gonzalez Saez‐Diez, Amy Tam, Siofra Carty, Monica Ferrer Socorro, Kathryn Yang, Darius Ebrahimi‐Fakhari   +5 more
wiley   +1 more source

Chromosomal aberrations in P242R-expressing cells.

, 2012
Representative metaphase spread of MCF10A expressing (A.) WT or (B.) P242R Pol β. Chromosomal fusions are shown with the gray arrow and fragments are shown with black arrows. C. Number of aberrations per metaphase.
Jennifer Yamtich (122307), Joann B. Sweasy (31229), Antonia A. Nemec (122310), Agnes Keh (122315)   +3 more
core   +1 more source

Measuring Blood Plasma Glutamine Levels Using a Nanopore‐Based Sensor

Advanced Healthcare Materials, EarlyView.
Glutamine (GLN) is a biomarker useful for predicting toxic ammonia accumulation. Here, we used a biosensor based on the Cytolysin A (ClyA) nanopore coupled with the GLN‐specific protein substrate‐binding domain 2 (SBD2) to demonstrate real‐time measurement of GLN in blood plasma, highlighting the potential for future point‐of‐care applications ...
Sofia B. Relvas, Iris M. Kormelink, Sandra Michel‐Souzy, Florian L. R. Lucas, Nieck J. van der Heide, Hans R. Waterham, Ramon Versteeg, Judith Jans, Loes I. Segerink, Carsten Wloka   +9 more
wiley   +1 more source

Analysis of Chromosomal Aberrations and FLT3 gene Mutations in Childhood Acute Myelogenous Leukemia Patients

Turkish Journal of Hematology, 2012
OBJECTIVE: To identify the well-known common translocations and FLT3 mutations in childhood acute myelogenous leukemia (AML) patients in Turkey. METHODS: The study included 50 newly diagnosed patients in which t(15;17), t(8;21), and inv(16) chromosomal ...
Ender Coşkunpınar, Sema Anak, Leyla Ağaoğlu, Ayşegül Ünüvar, Ömer Devecioğlu, Gönül Aydoğan, Çetin Timur, Ahmet Faik Öner, Yıldız Yıldırmak, Tiraje Celkan, İnci Yıldız, Nazan Sarper, Uğur Özbek   +12 more
doaj   +1 more source