Results 141 to 150 of about 119,383 (327)

Detection of genetic imbalances in tumor genomes by fluorescence in situ hybridization with tumor genomic DNA and subregional DNA probes [PDF]

open access: yes, 1993
Cremer, Thomas   +12 more
core   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

Genotoxic effects among petrol station workers.

open access: yesمجلة كلية الطب, 2007
Background: Benzene has been internationally recognized as a potent toxin, particularly for its effects on the blood forming system of the bone marrow and its association to a large number of haematological disorders. Aims: This study aimed to assess the
Abdul-Hussain M. Al-Faisal
doaj  

Modern and Ancient Genomes Reveal Neolithic Paternal Expansions of Millet and Rice Farmers and Demic Diffusion from China into Mainland Southeast Asia

open access: yesAdvanced Science, EarlyView.
This study clarifies the genetic patterns of paternal lineages across East Asia and Mainland Southeast Asia. Han populations are relatively homogeneous, whereas southern ethnolinguistic minorities display regional structures. Shared Y‐chromosome lineages indicate Neolithic expansions and extensive north‐south gene flow, supporting demic diffusion ...
Yunhui Liu   +15 more
wiley   +1 more source

Single‐Cell Transcriptomics Reveals FLS2‐Dependent Hypoxia Signaling and ERF13‐Mediated Transcription During flg22‐Triggered Immunity

open access: yesAdvanced Science, EarlyView.
This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou   +17 more
wiley   +1 more source

TOGR3, a Proteasome β4 Subunit, Orchestrates Sugar Homeostasis to Trade Off Growth and Thermotolerance in Rice

open access: yesAdvanced Science, EarlyView.
This study identifies a novel thermoregulatory mechanism in rice: TOGR3 partners with 26S proteasome subunits, including TT1, to drive thermoresponsive ubiquitin–proteasome activity, maintaining sugar homeostasis in stomatal regulation to balance growth and stress resistance.
Biyao Zhang   +9 more
wiley   +1 more source

Cytogenic studies of blood (experiment M111) [PDF]

open access: yes
The Skylab M111 experiment was a continuation of the preflight and postflight chromosomal analyses of the flight crews that have been performed since the Gemini 3 mission.
Lockhart, L. H.
core   +1 more source

Chromosome aberrations after etoposide containing cisplatin-based chemotherapy for malignant germ-cell tumours

open access: bronze, 2000
Alicia Hernández   +4 more
openalex   +1 more source

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