Results 151 to 160 of about 946,819 (342)

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto   +20 more
wiley   +1 more source

Genotoxic effects among petrol station workers.

open access: yesمجلة كلية الطب, 2007
Background: Benzene has been internationally recognized as a potent toxin, particularly for its effects on the blood forming system of the bone marrow and its association to a large number of haematological disorders. Aims: This study aimed to assess the
Abdul-Hussain M. Al-Faisal
doaj  

Cytogenic studies of blood (experiment M111) [PDF]

open access: yes
The Skylab M111 experiment was a continuation of the preflight and postflight chromosomal analyses of the flight crews that have been performed since the Gemini 3 mission.
Lockhart, L. H.
core   +1 more source

Detection of Chromosomal Aberrations in Clinical Practice: From Karyotype to Genome Sequence.

open access: yesAnnual review of genomics and human genetics (Print), 2015
C. Martin, D. Warburton
semanticscholar   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

open access: yesAdvanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao   +14 more
wiley   +1 more source

A survey on the possibility of utilizing γH2AX as a biodosimeter in radiation workers [PDF]

open access: yes, 2015
Introduction DNA damage is among the main consequences of radiation. Of many different classes of DNA damage, double-strand breaks are the most deleterious.
Asadi, J.   +3 more
core  

Patterns of Chromosomal Aberrations in Solid Tumors.

open access: yesRecent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 2015
M. Grade, M. Difilippantonio, J. Camps
semanticscholar   +1 more source

Genome‐Wide Association Study Reveals Insect Genetics and Microbial Symbiont Effects on Susceptibility of Diaphorina citri to the Citrus Greening Pathogen, Candidatus Liberibacter Asiaticus

open access: yesAdvanced Science, EarlyView.
This study investigates the genetic and microbial factors influencing the susceptibility of Diaphorina citri to the citrus greening pathogen Candidatus Liberibacter asiaticus (CLas), employing a microbiome Genome Wide Association Study. The research identifies a key gene encoding an MFS‐type transporter contributing to CLas infectivity and abundance in
Kai Liu   +12 more
wiley   +1 more source

Mapping Genetic Regulation of Transcription to Identify Functional Variants and Genes Associated with Pancreatic Cancer Risk

open access: yesAdvanced Science, EarlyView.
Integration of a pancreatic eQTL map with a GWAS meta‐analysis identifies 82 putative functional variants and 15 genes. The association between rs11102484 and pancreatic cancer risk is observed in a total of 5699 cases and 8467 controls. The G allele of rs11102484 weakens ZNF263 binding and the silencer‐promoter interaction, thereby increasing ST7L ...
Xiaoyang Wang   +14 more
wiley   +1 more source

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