Results 171 to 180 of about 246,792 (294)

Integrated Multi‐Omics Reveals Cellular States and Microenvironmental Remodeling in Coexisting DCIS and IDC

open access: yesAdvanced Science, EarlyView.
Coexisting DCIS and IDC samples are profiled using spatial transcriptomics, single‐cell RNA sequencing, and single‐cell DNA sequencing. Integrative multi‐omics analysis reveals distinct malignant epithelial and microenvironmental features between DCIS and IDC, which are further validated using Xenium and multiplex immunohistochemistry.
Ning Zhang   +18 more
wiley   +1 more source

Chromosomal aberrations in traverse factory workers

open access: yes, 1993
Bu tezin, veri tabanı üzerinden yayınlanma izni bulunmamaktadır. Yayınlanma izni olmayan tezlerin basılı kopyalarına Üniversite kütüphaneniz aracılığıyla (TÜBESS üzerinden) erişebilirsiniz.Sağlık Bilimleri Enstitüsü, Tıbbi Biyoloji ve Genetik Ana Bilim ...
Koçkaya, Semra
core  

ERα–PADI4–CXCL8 Axis Drives MDSC‐Mediated Immune Evasion in Anaplastic Thyroid Carcinoma

open access: yesAdvanced Science, EarlyView.
MAPK‐driven ligand‐independent ERα activation drives PADI4 transcription and translation. This enzyme then modifies CXCL8 chemokines through citrullination, generating a potent chemoattractant gradient specifically for myeloid‐derived suppressor cells.
Dongdong Zhang   +5 more
wiley   +1 more source

Chromosomal Aberrations in Fetuses With Isolated Persistent Right Umbilical Vein-A Nationwide Study. [PDF]

open access: yesPrenat Diagn
Vedel C   +7 more
europepmc   +1 more source

GSLR Drives Lung Adenocarcinoma as a Critical Regulator of Energy Homeostasis Through Creatine Kinase B Activation

open access: yesAdvanced Science, EarlyView.
This study identifies the glucose/glutamine sensitive lncRNA GSLR as a driver of lung adenocarcinoma progression. Nutrient restriction reduces chromatin accessibility at the GSLR locus and blocks CTCF‐mediated transcriptional regulation. GSLR directly interacts with DHX9 and recruits it to the CKB promoter, arresting R‐loop accumulation and promoting ...
Xinyi Qian   +9 more
wiley   +1 more source

Thermal Shifts Dominate Single‐Gene Responses to Transcription‐Targeting Antibiotics

open access: yesAdvanced Science, EarlyView.
Thermal shifts reshape bacterial responses to transcription‐targeting antibiotics. In E. coli, temperature can dominate antibiotic‐induced genome‐wide expression, particularly outside 30°C–39°C, through changes in adenosine triphosphate (ATP), nucleoid organization, and drug‐target engagement.
Rahul Jagadeesan   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy