Results 141 to 150 of about 946,819 (342)

REALIZATION OF THE PHENOTYPIC EFFECT OF CHROMOSOMAL ABERRATIONS IN HUMANS

Вавиловский журнал генетики и селекции, 2014
Factors determining the phenotype formation in patients with abnormal karyotype (including those with Down’s syndrome) have been discussed for several decades.
K. N. Grinberg, V. I. Kukharenko
doaj  

Evaluation of oxidative stress and genetic instability among residents near mobile phone base stations in Germany

Ecotoxicology and Environmental Safety
Human exposure to radiofrequency electromagnetic fields (RF-EMF) is restricted to prevent thermal effects in the tissue. However, at very low intensity exposure ''non-thermal'' biological effects, like oxidative stress, DNA or chromosomal aberrations ...
Sachin Gulati, Wilhelm Mosgoeller, Dietrich Moldan, Pavol Kosik, Matus Durdik, Lukas Jakl, Milan Skorvaga, Eva Markova, Dominika Kochanova, Katarina Vigasova, Igor Belyaev   +10 more
doaj   +1 more source

Prognostic impact of chromosomal aberrations and GNAQ, GNA11 and BAP1 mutations in uveal melanoma

Acta ophthalmologica, 2018
Kjersti M Staby, K. Gravdal, S. Mørk, S. Heegaard, O. Vintermyr, J. Krohn   +5 more
semanticscholar   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

Advanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha, Linda Kloss, Juan D. Montenegro, Simone Albani, Audrey Ortega‐Ramírez, Mihaela Raycheva, Sylvia Joussen, Sabrina Kaul, Michèle Bachmann, Lisa Huf, Günther Schmalzing, Alison G. Cole, Ulrich Technau, Stefan Gründer   +13 more
wiley   +1 more source

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

Advanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

Chromosomal Aberrations in Large Japanese Field Mice (Apodemus speciosus) Captured near Fukushima Dai-ichi Nuclear Power Plant.

Environmental Science and Technology, 2017
Taiki Kawagoshi, N. Shiomi, H. Takahashi, Yoshito Watanabe, S. Fuma, Kazutaka Doi, I. Kawaguchi, M. Aoki, Masahide Kubota, Yoshiaki Furuhata, Yusaku Shigemura, M. Mizoguchi, F. Yamada, Morihiko Tomozawa, Shinsuke H. Sakamoto, S. Yoshida, Y. Kubota   +16 more
semanticscholar   +1 more source

Single‐Cell Transcriptomics Reveals FLS2‐Dependent Hypoxia Signaling and ERF13‐Mediated Transcription During flg22‐Triggered Immunity

Advanced Science, EarlyView.
This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou, Aizhi Qin, Mengfan Li, Qianli Zhao, Luyao Kong, Lulu Yan, Chunyang Li, Hao Liu, Yinpeng Zhang, Jiani Long, Mengyu Liao, Mengmeng Zhou, Xiaoli Fan, Baozhen Wang, Wenxuan Kang, Shui Wang, Zhixin Liu, Xuwu Sun   +17 more
wiley   +1 more source

Proliferative behaviour and cytogenetic changes in human renal-cell carcinoma [PDF]

, 1991
Allhoff, E. P., Azpodien, J., Djamilian, Mohamad H., Jonas, Udo, Kirchner, H., Riese, W. de, Schlick, R. W., Stief, Christian Georg, Werner, M.   +8 more
core   +1 more source

chromosomal aberration

Citation: 'chromosomal aberration' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15558 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source