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Sperm and Oocyte Chromosomal Abnormalities [PDF]

Biomolecules, 2023
Gametogenesis, the process of producing gametes, differs significantly between oocytes and sperm. Most oocytes have chromosomal aneuploidies, indicating that chromosomal aberrations in miscarried and newborn infants are of oocyte origin. Conversely, most
Osamu Samura, Yoshiharu Nakaoka, Norio Miharu   +2 more
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Chromosomal Abnormalities in Couples Experiencing Recurrent Implantation Failure in West of Iran: A Case–Control Study [PDF]

Molecular Genetics & Genomic Medicine
Background Recurrent Implantation Failure (RIF) is defined as the inability to establish pregnancy despite high‐quality embryo transfer after the application of at least three consecutive in vitro fertilization (IVF)/intracytoplasmic sperm injection ...
Atefeh Asgari, Amir Mohammad Salehi, Fatemeh Shahbazi, Safieh Ghahremani, Ebrahim Kamrani Saleh   +4 more
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Chromosomal Abnormalities Detected by Chromosomal Microarray Analysis and Karyotype in Fetuses with Ultrasound Abnormalities [PDF]

International Journal of General Medicine
Liubing Lan,1,2 Dandan Luo,1,2 Jianwen Lian,1 Lingna She,1,3 Bosen Zhang,1,3 Hua Zhong,1 Huaxian Wang,1 Heming Wu1 1Department of Prenatal Diagnostic Center, Meizhou People’s Hospital, Meizhou, People’s Republic of China; 2Department of Obstetrics ...
Lan L, Luo D, Lian J, She L, Zhang B, Zhong H, Wang H, Wu H   +7 more
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Chromosomal Abnormalities in Early Pregnancy Losses: A Study of 900 Samples [PDF]

Balkan Journal of Medical Genetics, 2023
Chromosomal abnormalities are the most common causes of early pregnancy losses (EPLs). In this study, we aimed to evaluate the incidence and spectrum of chromosomal abnormalities in EPLs and correlate them with different clinical characteristics.
Bozhinovski Gj, Terzikj M, Kubelka-Sabit K, Jasar Dz, Lazarevski S, Livrinova V, Plaseska-Karanfilska D   +6 more
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Retrospective study revealed integration of CNV-seq and karyotype analysis is an effective strategy for prenatal diagnosis of chromosomal abnormalities [PDF]

Frontiers in Genetics
Fetal chromosomal abnormalities are the main cause of adverse pregnancy outcomes and are the focus of invasive prenatal diagnosis. Recent studies have demonstrated that various techniques have distinct advantages.
Yunsheng Ge, Jiayan Chen, Yanru Huang, Di Shao, Wenbo Wang, Meijiao Cai, Meihua Tan, Meihua Tan, Jian Zhang   +8 more
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Chromosomal Abnormalities in Miscarriages and Maternal Age: New Insights from the Study of 7118 Cases [PDF]

Cells
Chromosomal abnormalities of the embryo are the most common cause of first-trimester pregnancy loss. In this single-center study, we assessed the frequency and the spectrum of chromosomal abnormalities in miscarriages for each year of maternal age from ...
Anna A. Pendina, Mikhail I. Krapivin, Olga G. Chiryaeva, Lubov’ I. Petrova, Elizaveta P. Pashkova, Arina V. Golubeva, Andrei V. Tikhonov, Alla S. Koltsova, Ekaterina D. Trusova, Dmitrii A. Staroverov, Andrey S. Glotov, Olesya N. Bespalova, Olga A. Efimova   +12 more
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Internet-Based Abnormal Chromosomal Diagnosis During Pregnancy Using a Noninvasive Innovative Approach to Detecting Chromosomal Abnormalities in the Fetus: Scoping Review [PDF]

JMIR Bioinformatics and Biotechnology
BackgroundChromosomal abnormalities are genetic disorders caused by chromosome errors, leading to developmental delays, birth defects, and miscarriages.
Mega Obukohwo Sr Oyovwi, Ejiro Peggy Ohwin, Rume Arientare Rotu, Temitope Gideon Olowe   +3 more
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Retrospective analysis of the sex chromosomal copy number variations in 186 fetuses using single nucleotide polymorphism arrays

Frontiers in Genetics, 2022
Sex chromosomal abnormalities are associated with multiple defects. However, the types of sex chromosomal abnormalities during pregnancy in Fujian Province, China, are not recorded.
Haiwei Wang, Bin Liang, Yan Wang, Hailong Huang, Na Lin, Liangpu Xu   +5 more
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Rare chromosomal abnormalities: Can they be identified using conventional first trimester combined screening methods?

European Journal of Obstetrics & Gynecology and Reproductive Biology: X, 2021
Objective: To evaluate the performance of first trimester combined screening for the detection of rare chromosomal abnormalities, other than Trisomies 21, 18 or 13 or 45 × . Study design: A database containing 36,254 pregnancies was analyzed.
Daniel Kane, Mary E. D’Alton, Fergal D. Malone   +2 more
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Cytogenetic Analysis for Suspected Chromosomal Abnormalities; A Five Years Experience [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Chromosomal abnormalities are the results of alterations in the number or structure of chromosomes causing significant human morbidity and mortality.
Sunil Kumar Polipalli, Vijay Kumar Karra, Ankur Jindal, Madhavi Puppala, Pratiksha Singh, Kanchan Rawat, Seema Kapoor   +6 more
doaj   +1 more source