Results 41 to 50 of about 2,948,023 (230)

Associations of recurrent miscarriages with chromosomal abnormalities, thrombophilia allelic polymorphisms and/or consanguinity in Saudi Arabia

BMC Medical Genetics, 2016
BackgroundRecurrent pregnancy loss (RPL) or recurrent spontaneous abortion is an obstetric complication that affects couples at reproductive age. Previous reports documented a clear relationship between parents with chromosomal abnormalities and both ...
R. Turki, Mourad Assidi, H. Banni, H. Zahed, Sajjad Karim, Hans-Juergen Schulten, Muhammad Muhammad Abu-Elmagd, A. Rouzi, O. Bajouh, H. Jamal, Mohammed H Al-Qahtani, Adel M. Abuzenadah   +11 more
semanticscholar   +1 more source

Chromosomal Aberrations and Polymorphic Evaluation in Males with Primary Infertility from Indian Population [PDF]

Journal of Clinical and Diagnostic Research, 2014
Background and objectives: The chromosomal abnormalities are one of the important causes of male infertility. In view of the genetic risks for the next generation, the importance of careful evaluation of karyotype is essential.
Ushang V. Kate, Yamini S. Pokale, Ajinkya M. Jadhav, Suresh D. Gangane   +3 more
doaj   +1 more source

Chromosomal abnormalities and Y chromosome microdeletions in infertile men from Morocco

BMC Urology, 2015
BackgroundMale infertility is responsible for 50 % of infertile couples. Thirty percent of male infertility is due to cytogenetic and genetic abnormalities.
Yassine Naasse, H. Charoute, B. El Houate, Chadli Elbekkay, Lunda Razoki, Abderrahim Malki, A. Barakat, H. Rouba   +7 more
semanticscholar   +1 more source

Cytogenetics evaluation of 261 couples with first-trimester recurrent pregnancy loss: A prevalent case–control study

Journal of Marine Medical Society, 2023
Introduction: Recurrent pregnancy loss (RPL) is a common occurrence which affects approximately 15-20% of couples. Chromosomal abnormality is an important cause of recurrent abortions especially if either of the partner is a carrier of balanced ...
Paresh Singhal, S K Raghavendra, Barun Kumar Chakrabarty, Ganesh Pendkur, Chinmay Shrikrishna Pendharkar, Gurpreet Kaur Sagoo   +5 more
doaj   +1 more source

Chromosomal abnormalities and psychosis [PDF]

British Journal of Psychiatry, 2006
SummaryThe search for susceptibility genes for schizophrenia and severe affective disorder has been enhanced by the study of cytogenetic abnormalities that disrupt genes directly. One such gene is DISCI and there is increasing evidence that it may be an important modulator of risk of psychosis.
Muir, Walter J., Pickard, Benjamin S., Blackwood, Douglas H.R.   +2 more
openaire   +4 more sources

Retrospective study revealed integration of CNV-seq and karyotype analysis is an effective strategy for prenatal diagnosis of chromosomal abnormalities

Frontiers in Genetics
Fetal chromosomal abnormalities are the main cause of adverse pregnancy outcomes and are the focus of invasive prenatal diagnosis. Recent studies have demonstrated that various techniques have distinct advantages.
Yunsheng Ge, Jiayan Chen, Yanru Huang, Di Shao, Wenbo Wang, Meijiao Cai, Meihua Tan, Meihua Tan, Jian Zhang   +8 more
doaj   +1 more source

Chromosomal Abnormalities in Infertile Men from Southern India.

Journal of clinical and diagnostic research : JCDR, 2015
BACKGROUND AND OBJECTIVE Male infertility has been associated with aneuploidies and structural chromosomal abnormalities, Yq microdeletions and specific gene mutations and/or polymorphisms.
J. Suganya, Smita Kujur, Kamala Selvaraj, Muthiah S. Suruli, G. Haripriya, Chandra R. Samuel   +5 more
semanticscholar   +1 more source

Chromosomal microarray analysis in 1292 fetuses with ultrasound soft markers during mid-term pregnancy

The Journal of Maternal-Fetal & Neonatal Medicine
Background Soft markers found during mid-term pregnancy ultrasounds can indicate potential chromosomal abnormalities in fetuses. This study evaluates the association between ultrasound soft markers and chromosomal abnormalities, providing insights into ...
Xiaomei Yang, Li Sun, Yasong Xu, Shiyu Sun, Shoulan Zhou, Ping Lv   +5 more
doaj   +1 more source

Clinical Correlates of Autosomal Chromosomal Abnormalities in an Electronic Medical Record–Linked Genome-Wide Association Study

Journal of Investigative Medicine High Impact Case Reports, 2013
Although mosaic autosomal chromosomal abnormalities are being increasingly detected as part of high-density genotyping studies, the clinical correlates are unclear.
Hayan Jouni M.D., Khader Shameer Ph.D., Yan W. Asmann Ph.D., Ribhi Hazin M.D., Mariza de Andrade Ph.D., Iftikhar J. Kullo M.D.   +5 more
doaj   +1 more source

Reproductive outcomes of infertile couples undergoing assisted reproductive technology who are carriers of chromosomal abnormalities: a retrospective cohort study

Annals of Medicine, 2022
Background The aim of this study is to determine whether infertile couples who are carriers of chromosomal abnormalities have distinct cumulative clinical pregnancy and cumulative live birth rates among patients undergoing assisted reproductive ...
Ling Cui, Fang Wang, Yonghong Lin, Min Li   +3 more
doaj   +1 more source