Results 101 to 110 of about 2,524,105 (337)

Structural Chromosomal Abnormalities in Couples with Recurrent Pregnancy Loss [PDF]

, 2010
Objective: Recurrent pregnancy loss is an important problem affecting couples trying to conceive. Genetic factors, particularly chromosomal abnormalities appear to be highly associated with reproductive loss.
Cirakoglu, Ayse, Tarkan-Arguden, Yelda, Ayşe ÇIRAKOĞLU, Kuru, Dilhan, Uludag, Seyfettin, Ayhan DEVİREN, Dilhan KURU, Gülgün S. GÜVEN, Yilmaz, Sukriye, Guven, Gulgun S., Şükriye YILMAZ, Yelda - TARKAN-ARGÜDEN, Seyfettin ULUDAĞ, Deviren, Ayhan, Seniha HACIHANEFİOĞLU, Hacihanefioglu, Seniha   +15 more
core   +1 more source

Study of Chromosomal Abnormalities in Couples with Recurrent Spontaneous Abortions (RSA) in Ardabil Province

Journal of Ardabil University of Medical Sciences, 2018
Background & objectives: The spontaneous abortion, loss of the fetus until the twentieth week of pregnancy, is one of the most common medical problems in reproductive age.
Ziba Jahani, Seyyed saeid Hosseini Asl, Homa Akhavan   +2 more
doaj  

Chromosomal Abnormalities in Idiopathic Mental Retardation Patients at a Charity Center in Hamadan, Iran

Avicenna Journal of Medical Biochemistry, 2016
Background Chromosomal aberrations are one of the most common causes of mental retardation (MR). Objectives In this study, in order to identify the rate of chromosomal abnormalities in idiopathic MR, 50 MR ...
Etemadi
doaj   +1 more source

Chromosomal abnormalities associated with fetal megacystis [PDF]

Fetal megacystis has been reported to be associated with chromosomal abnormalities, megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS), obstructive uropathy, prune belly syndrome, cloacal anomalies, limb-body wall complex, amniotic band ...
Chih-Ping Chen
core   +1 more source

Chromosomal abnormalities in 163 Tunisian couples with recurrent miscarriages [PDF]

, 2017
Recurrent miscarriage (RM) is defined as three or more consecutive pregnancy losses before 24 weeks of gestation. Parental chromosomal abnormalities represent an important etiology of RM.
Ayed, Wiem, Guermani, Helmy, Chemkhi, Imen, Obay, Rim, Messaoudi, Islem, Belghith, Zouhour, Hammami, Wajih, Amouri, Ahlem, Abidli, Nabila   +8 more
core   +2 more sources

Evaluation of chromosomal abnormalities in the postnatal cohort: A single-center study on 14,242 patients. [PDF]

J Clin Lab Anal
Background and AimChromosomal analysis is a laboratory technique used to examine the chromosomes of an individual, offering insights into chromosome numbers, structures, and arrangements to diagnose and comprehend genetic diseases.
Akalin H, Sahin IO, Paskal SA, Tan B, Yalcinkaya E, Demir M, Yakubi M, Caliskan BO, Ekinci OG, Ercan M, Kucuk TY, Gokgoz G, Kiraz A, Per H, Ozgun MT, Baydilli N, Ozkul Y, Dundar M.   +17 more
europepmc   +2 more sources

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

The dark side of centromeres: types, causes and consequences of structural abnormalities implicating centromeric DNA

Nature Communications, 2018
Centromeres are the chromosomal domains required to ensure faithful transmission of the genome during cell division. They have a central role in preventing aneuploidy, by orchestrating the assembly of several components required for chromosome separation.
V. Barra, D. Fachinetti
semanticscholar   +1 more source

Internet-Based Abnormal Chromosomal Diagnosis During Pregnancy Using a Noninvasive Innovative Approach to Detecting Chromosomal Abnormalities in the Fetus: Scoping Review

JMIR Bioinformatics and Biotechnology
BackgroundChromosomal abnormalities are genetic disorders caused by chromosome errors, leading to developmental delays, birth defects, and miscarriages.
Mega Obukohwo Sr Oyovwi, Ejiro Peggy Ohwin, Rume Arientare Rotu, Temitope Gideon Olowe   +3 more
doaj   +1 more source