Results 21 to 30 of about 111,505 (234)

Prevalence and patterns of chromosomal abnormalities among Egyptian patients with infertility: a single institution’s 5-year experience

Middle East Fertility Society Journal, 2022
Background Chromosomal abnormalities represent an important cause of human infertility. Little is known about the prevalence of chromosomal abnormalities among Egyptian couples with infertility.
Faeza El-Dahtory, Sohier Yahia, Rabab Ahmed Rasheed, Yahya Wahba   +3 more
doaj   +1 more source

Study on Types of Chromosomal Abnormalities among Children and Adolescents in Hamadan

پژوهان, 2021
Aims: Problems caused by chromosomal abnormalities along with long-term disabilities can have devastating effects on the patient, family, health care system and society.
Fatemeh Bahreini, Negar Shamloei, Razieh Amini   +2 more
doaj  

Additional chromosome abnormalities in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy

Haematologica, 2010
Background Acute promyelocytic leukemia is a subtype of acute myeloid leukemia characterized by the t(15;17). The incidence and prognostic significance of additional chromosomal abnormalities in acute promyelocytic leukemia is still a controversial ...
José Cervera, Pau Montesinos, Jesús M. Hernández-Rivas, María J. Calasanz, Anna Aventín, María T. Ferro, Elisa Luño, Javier Sánchez, Edo Vellenga, Chelo Rayón, Gustavo Milone, Javier de la Serna, Concha Rivas, José D. González, Mar Tormo, Elena Amutio, Marcos González, Salut Brunet, Bob Lowenberg, Miguel A. Sanz   +19 more
doaj   +1 more source

Clinical application of single nucleotide polymorphism microarray analysis in pregnancy loss in Northwest China

Frontiers in Genetics, 2023
Background: Spontaneous abortion is the most common complication of early pregnancy. In this study, we aim to investigate the clinical application value of genetic diagnosis using single nucleotide polymorphism (SNP) microarray analysis on the products ...
ShuYuan Xue, ShuYuan Xue, LiXia Wang, Jie Wei, YuTong Liu, GuiFeng Ding, PengGao Dai   +6 more
doaj   +1 more source

Chromosome Abnormalities

Veterinary Clinics of North America: Food Animal Practice, 1993
Chromosome abnormalities have been described in food animals since 1964. Some are self-limiting because they cause sterility or other developmental defects incompatible with normal growth and development, making them unacceptable for production systems.
openaire   +2 more sources

Cytogenetics evaluation of 261 couples with first-trimester recurrent pregnancy loss: A prevalent case–control study

Journal of Marine Medical Society, 2023
Introduction: Recurrent pregnancy loss (RPL) is a common occurrence which affects approximately 15-20% of couples. Chromosomal abnormality is an important cause of recurrent abortions especially if either of the partner is a carrier of balanced ...
Paresh Singhal, S K Raghavendra, Barun Kumar Chakrabarty, Ganesh Pendkur, Chinmay Shrikrishna Pendharkar, Gurpreet Kaur Sagoo   +5 more
doaj   +1 more source

Clinicopathological analysis of polyploid diffuse large B-cell lymphoma. [PDF]

PLoS ONE, 2018
Polyploid chromosomes are those with more than two sets of homologous chromosomes. Polyploid chromosomal abnormalities are observed in various malignant tumors. The prognosis in such cases is generally poor.
Joji Shimono, Hiroaki Miyoshi, Junichi Kiyasu, Tomohiko Kamimura, Tetsuya Eto, Takuto Miyagishima, Koji Nagafuji, Masao Seto, Takanori Teshima, Koichi Ohshima   +9 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Additional chromosomal abnormalities in Philadelphia-positive chronic myeloid leukemia

Hematology/Oncology and Stem Cell Therapy, 2008
BACKGROUND AND OBJECTIVE: The emergence of non-random chromosomal abnormalities is a well-rec-ognized occurrence in chronic myeloid leukemia (CML) and detection of these abnormalities is important in prognostic stratification.
Naveen Naz Syed, Mohammad Usman, Salman Adil, Mohammad Khurshid   +3 more
doaj   +1 more source

Chromosomal Aberrations and Polymorphic Evaluation in Males with Primary Infertility from Indian Population [PDF]

Journal of Clinical and Diagnostic Research, 2014
Background and objectives: The chromosomal abnormalities are one of the important causes of male infertility. In view of the genetic risks for the next generation, the importance of careful evaluation of karyotype is essential.
Ushang V. Kate, Yamini S. Pokale, Ajinkya M. Jadhav, Suresh D. Gangane   +3 more
doaj   +1 more source