Results 21 to 30 of about 68,433 (279)

A Rare Chromosome Abnormality with der(16)t(1;16)(q12;q11.2) in Blast Crisis of Chronic Myeloid Leukemia

Case Reports in Oncology, 2020
Although tyrosine kinase inhibitors markedly improve the clinical outcome of chronic myeloid leukemia (CML), blast crisis in CML (CML-BC) still has a poor prognosis.
Ryo Yanagiya, Daisuke Ishikawa, Tomomi Toubai, Tsubasa Ichikawa, Naofumi Kawaguchi, Kunie Sugasawa, Kenichi Ishizawa, Soichi Saito   +7 more
doaj   +1 more source

Polymorphism in glutathione S-transferase P1 is associated with susceptibility to chemotherapyinduced leukemia [PDF]

, 2001
Glutathione S-transferases (GSTs) detoxify potentially mutagenic and toxic DNA-reactive electrophiles, including metabolites of several chemotherapeutic agents, some of which are suspected human carcinogens.
Allan, J.M., Wild, C.P., Rollinson, S., Willett, E.V., Moorman, A.V., Dovey, G.J., Roddam, P.L., Roman, E., Cartwright, R.A., Morgan, G.J.   +9 more
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Unexplained Pancytopenia in a Patient with 5q35.2-q35.3 Microduplication Encompassing NSD1: A Case Report

International Journal of Hematology-Oncology and Stem Cell Research, 2018
The 5q35.2-q35.3 duplication phenotype is characterized by growth delay, microcephaly, mental retardation and delayed bone aging. However, there has been no reports on the occurrence of pancytopenia as a consequence of 5q35.2-q35.3 duplication. A 42-year-
Sungwoo Park, Gyeong-Won Lee, Eun-Ha Koh, Hyun-Young Kim   +3 more
doaj   +1 more source

The use of an e-learning constructivist solution in workplace learning [PDF]

, 2009
We wished to investigate whether an e-learning approach which uses constructivist principles can be successfully applied to train employees in a highly specialised skill thought to require expert individuals and extensive prolonged training. The approach
A. Mileham, A.M. Payne, Anderson, Atkinson, Brown, Brown, Carroll, Carroll, D.K. Griffin, de Jong, Dewhurst, Ducos, Ducos, Ducos, Ducos, Duffy, Farmer, Gibbons, Gibbons, Green, H.G. Tempest, Heerman, Holt, Hughes, Ivancic, J.E. Stephenson, Jonassen, Knowles, Knowles, Kofman, Leathard, Maury, Miller, Modell, Pinton, Popescu, Quilter, Rieber, Smith, van Merrienboer, W.B. Morris, Wang, Wolstenholme   +42 more
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Clinical Significance of Application of Chromosomal Karyotyping of Villus Tissues

International Journal of Women's Health, 2023
Shuyun Zhang,1,* Lijuan Wu,1,* Xue Li,1 Li Yang,1 Sujuan Shen,1 Hong Shen,1 Dan Zhao,2 Lin Qi2,3 1Center of Reproductive Medicine, The Second Affiliated Hospital of Soochow University, Su Zhou, People’s Republic of China; 2Precision Medicine ...
Zhang S, Wu L, Li X, Yang L, Shen S, Shen H, Zhao D, Qi L   +7 more
doaj  

Chromosomal aberrations in transitional cell carcinoma that are predictive of disease outcome are independent of polyploidy [PDF]

, 1999
Objective To determine whether aneusomy for chromosomes 7, 9 and 17 (reported to predict recurrence in up to 65% of patients with superficial transitional cell bladder cancer and thus providing the opportunity for early and effective treatment) reflects ...
Adie, L., Bartlett, J.M.S., Going, J.J., Grigor, K.M., Watters, A.D.   +4 more
core   +1 more source

Concordance of copy number abnormality detection using SNP arrays and Multiplex Ligation-dependent Probe Amplification (MLPA) in acute lymphoblastic leukaemia [PDF]

, 2020
In acute lymphoblastic leukaemia, MLPA has been used in research studies to identify clinically relevant copy number abnormality (CNA) profiles. However, in diagnostic settings other techniques are often employed.
Bashton, Matthew, Enshaei, Amir, Harrison, Christine J., Hollis, Robin, Moorman, Anthony V., Moppett, John, Ryan, Sarra, Schwab, Claire J.   +7 more
core   +1 more source

An overview of a 30-year experience with amniocentesis in a single tertiary medical center in Taiwan

Taiwanese Journal of Obstetrics & Gynecology, 2012
Objective: Amniocentesis is a popular and effective prenatal diagnostic tool for chromosomal disorders. It is well-established that the risk of chromosomal abnormalities increases with maternal age; however, other related indications are seldom reported.
Yi-Wen Chang, Chia-Ming Chang, Pi-Lin Sung, Ming-Jie Yang, Wai Hou Li, Hsin-Yang Li, Ling-Chao Chen, Ling-Yi Cheng, Yu-Ling Lai, Yung-Yung Cheng, Wen-Hsun Chang, Kuan-Chong Chao, Peng-Hui Wang   +12 more
doaj   +1 more source

Chromosomal analysis of 262 miscarried conceptuses: a retrospective study

BMC Pregnancy and Childbirth, 2022
Background Embryonic chromosomal abnormality is one of the significant causative factors of pregnancy loss. Our goal was to investigate the differences of chromosomal abnormality between different conception modes in miscarried products of conception ...
Juan Gui, Jinli Ding, Tailang Yin, Qian Liu, Qingzhen Xie, Lei Ming   +5 more
doaj   +1 more source

Array comparative genomic hybridization and flow cytometry analysis of spontaneous abortions and mors in utero samples [PDF]

, 2009
Background: It is estimated that 10-15% of all clinically recognised pregnancies result in a spontaneous abortion or miscarriage. Previous studies have indicated that in up to 50% of first trimester miscarriages, chromosomal abnormalities can be ...
Björn Menten, Katrien Swerts, Barbara Delle Chiaie, Sandra Janssens, Karen Buysse, Jan Philippé, Frank Speleman, T Hassold, V Jobanputra, M Goddijn, KA Bell, B Lomax, J Menasha, DL Bruno, D Diego-Alvarez, D Diego-Alvarez, DN Azmanov, M Daniely, B Fritz, Y Hu, A Kallioniemi, AC Tabet, J Berezowsky, B Menten, D Pinkel, S Solinas-Toldo, B Menten, K Benirschke, M Benkhalifa, M Nagaishi, AJ Schaeffer   +30 more
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