Results 31 to 40 of about 2,442,331 (340)

An overview of a 30-year experience with amniocentesis in a single tertiary medical center in Taiwan

Taiwanese Journal of Obstetrics & Gynecology, 2012
Objective: Amniocentesis is a popular and effective prenatal diagnostic tool for chromosomal disorders. It is well-established that the risk of chromosomal abnormalities increases with maternal age; however, other related indications are seldom reported.
Yi-Wen Chang, Chia-Ming Chang, Pi-Lin Sung, Ming-Jie Yang, Wai Hou Li, Hsin-Yang Li, Ling-Chao Chen, Ling-Yi Cheng, Yu-Ling Lai, Yung-Yung Cheng, Wen-Hsun Chang, Kuan-Chong Chao, Peng-Hui Wang   +12 more
doaj   +1 more source

Chromosomal analysis of 262 miscarried conceptuses: a retrospective study

BMC Pregnancy and Childbirth, 2022
Background Embryonic chromosomal abnormality is one of the significant causative factors of pregnancy loss. Our goal was to investigate the differences of chromosomal abnormality between different conception modes in miscarried products of conception ...
Juan Gui, Jinli Ding, Tailang Yin, Qian Liu, Qingzhen Xie, Lei Ming   +5 more
doaj   +1 more source

The use of an e-learning constructivist solution in workplace learning [PDF]

, 2009
We wished to investigate whether an e-learning approach which uses constructivist principles can be successfully applied to train employees in a highly specialised skill thought to require expert individuals and extensive prolonged training. The approach
A. Mileham, A.M. Payne, Anderson, Atkinson, Brown, Brown, Carroll, Carroll, D.K. Griffin, de Jong, Dewhurst, Ducos, Ducos, Ducos, Ducos, Duffy, Farmer, Gibbons, Gibbons, Green, H.G. Tempest, Heerman, Holt, Hughes, Ivancic, J.E. Stephenson, Jonassen, Knowles, Knowles, Kofman, Leathard, Maury, Miller, Modell, Pinton, Popescu, Quilter, Rieber, Smith, van Merrienboer, W.B. Morris, Wang, Wolstenholme   +42 more
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Pregnancy outcome following prenatal diagnosis of chromosomal anomaly: a record linkage study of 26,261 pregnancies [PDF]

, 2016
Previous studies have demonstrated the influence of changes in the age at which women give birth, and of developments in prenatal screening and diagnosis on the number of pregnancies diagnosed and terminated with chromosomal anomalies.
Cooper, Sally-Ann, Jacobs, Myrthe, McGowan, Ruth, Nelson, Scott, Pell, Jill P.   +4 more
core   +1 more source

Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21 [PDF]

, 2018
Intrachromosomal amplification of chromosome 21 is a heterogeneous chromosomal rearrangement occurring in 2% of childhood precursor B-cell acute lymphoblastic leukemia.
Bashton, Matthew, Blair, Helen H., Buechler, Lars, Carey, Peter, Cheng, Joanna, Clayton, Jake, Halsey, Christina, Hanna, Rebecca, Harrison, Christine J., Hawking, Zoe, Heidenreich, Olaf, Hollern, Shaun, Jones, Lisa, Marr, Helen, Moorman, Anthony V., Russell, Lisa J., Ryan, Sarra L., Schwab, Claire J., Sinclair, Paul B.   +18 more
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Studying Abnormal Chromosomal Diseases Using Patient-Derived Induced Pluripotent Stem Cells

Frontiers in Cellular Neuroscience, 2020
Chromosomal abnormality causes congenital and acquired intractable diseases. In general, there are no fundamental treatments for these diseases. To establish platforms to develop therapeutics for these diseases, patient-derived induced pluripotent stem ...
Yohei Hayashi, Miho Takami, Mami Matsuo-Takasaki   +2 more
doaj   +1 more source

Recurrent spontaneous abortion related to balanced translocation of chromosomes – A case report

Rwanda Medical Journal, 2023
INTRODUCTION: Recurrent spontaneous abortion (RSA) is defined as three or more consecutive pregnancy losses before the 20th week of gestation. RSA is often idiopathic, but structural chromosomal abnormality is an important cause.
N. Dukuze, B. Tuyishimire, H. Irere, B. Iradukunda, J. Ndinkabandi, C. Nsanzabaganwa, J. Mushingantahe, L. Mutesa   +7 more
doaj   +2 more sources

A Chromosomal Deletion and New Frameshift Mutation Cause ARSACS in an African-American [PDF]

, 2018
Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS) is a rare, progressive, neurodegenerative disease characterized by ataxia, spasticity and polyneuropathy.
Dougherty, Sean C., Haines, Scott R., Harper, Amy, Saif, Hind Al, Vorona, Gregory   +4 more
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A Chromosomal Inversion of 46XX, inv (6) (p21.3p23) Connects to Congenital Heart Defects

Frontiers in Cardiovascular Medicine, 2020
Congenital heart defects (CHDs) represent the most common human birth defects. Ventricular septal defect (VSD) is the most common subtype of CHDs. It has been shown that about 20–40% of VSDs are closely related to chromosomal aneuploidies or Mendelian ...
Liangping Cheng, Liangping Cheng, Liangping Cheng, Yanlai Tang, Yuese Lin, Hongjun Ba, Yiqian Ding, Dubo Chen, Min Liu, Peizhen Pan, Youzhen Qin, Zhan-Peng Huang, Zhan-Peng Huang   +12 more
doaj   +1 more source

Effectiveness of Chromosomal Microarray Analysis for Prenatal Diagnosis of Fetal Echogenic Intracardiac Focus: A Single-Center Experience

International Journal of General Medicine, 2021
Hailong Huang,1,* Meiying Cai,1,* Linyu Liu,1,2 Liangpu Xu,1 Na Lin1 1Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fujian Key Laboratory for Prenatal Diagnosis and Birth Defect, Fuzhou City, Fujian ...
Huang H, Cai M, Liu L, Xu L, Lin N
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