Results 201 to 210 of about 54,834 (268)

A disulfidptosis‐related gene signature predicts prognosis and immune‐metabolic landscape in multiple myeloma

British Journal of Haematology, EarlyView.
Summary Disulfidptosis is a newly recognized cell death induced by disulphide stress under glucose deprivation. However, its clinical implications in multiple myeloma (MM) remain largely unexplored. We identified disulfidptosis‐related genes via co‐expression analysis and developed a risk signature through univariate Cox, least absolute shrinkage and ...
Li Wang, Jinjin Wang, Yutong Wang, Ting Niu, Ailin Zhao   +4 more
wiley   +1 more source

Evaluating Chromosomal Mosaicism in Prenatal Diagnosis: The Complementary Roles of Chromosomal Microarray Analysis and Karyotyping. [PDF]

J Clin Lab Anal
Xu C, Xiong Y, Wang D, Zhang S, Wu X, Li M.   +5 more
europepmc   +1 more source

Prenatal Diagnosis Using Chromosomal Microarray Analysis in High-Risk Pregnancies. [PDF]

J Clin Med, 2022
Hsiao CH, Chen JS, Shiao YM, Chen YJ, Chen CH, Chu WC, Wu YC.   +6 more
europepmc   +1 more source

Practical Guidelines for Chromosomal Microarray Analysis for Constitutional Abnormalities: Part II, Reporting and Interpretation

, 2023
Dongju Won, Chang Ahn Seol, Jung‐Sook Ha, In‐Suk Kim   +3 more
openalex   +2 more sources

Integration of omics data in the diagnosis and therapy of glioblastoma

Brain Pathology, EarlyView.
Integration of omics data in the diagnosis and therapy of glioblastoma. Abstract Since the 2016 update of the WHO Classification of Tumors of the Central Nervous System, omics data have been officially integrated into the diagnostic process for glioblastoma, the most prevalent and aggressive primary malignant brain tumor in adults.
Constantin Möller, Melanie Schoof, Keith L. Ligon, Ulrich Schüller   +3 more
wiley   +1 more source

Utility of whole exome sequencing in the evaluation of isolated fetal growth restriction in normal chromosomal microarray analysis. [PDF]

Ann Med
Shi X, Huang Y, Ding H, Zhao L, He W, Wu J.   +5 more
europepmc   +1 more source

Diagnostic Value of Chromosomal Microarray Analysis for Fetal Congenital Heart Defects with Different Cardiac Phenotypes and Extracardiac Abnormalities. [PDF]

Diagnostics (Basel), 2023
Zhang S, Wang J, Pei Y, Han J, Xiong X, Yan Y, Zhang J, Liu Y, Su F, Xu J, Wu Q.   +10 more
europepmc   +1 more source

Identification of a distinct epigenetic subgroup with inferior PFS in intracranial mesenchymal tumors with FET::CREB fusion

Brain Pathology, EarlyView.
Six new cases of intracranial mesenchymal tumors with FET::CREB fusion, alongside 20 previously reported cases underwent DNA methylation profiling uncovered a novel epigenetic subgroup distinguished by inferior PFS and unique clinicopathological, molecular, and epigenetic hallmarks.
Yong Lin, Yun Ning, Yang Lan, Yu‐Juan Cao, Rui‐Jiao Zhao, Hai‐Nan Li, Song Duan, Wei‐Wei Fu, Hai‐Bo Wu, Feng Wu, Xiu‐Wu Bian, Tao Luo, Xiao‐Hong Yao   +12 more
wiley   +1 more source

DysRegNet: Patient‐specific and confounder‐aware dysregulated network inference towards precision therapeutics

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Gene regulation is frequently altered in diseases in unique and patient‐specific ways. Hence, personalised strategies have been proposed to infer patient‐specific gene‐regulatory networks. However, existing methods do not scale well because they often require recomputing the entire network per sample.
Johannes Kersting, Olga Lazareva, Zakaria Louadi, Jan Baumbach, David B. Blumenthal, Markus List   +5 more
wiley   +1 more source

The Positive Feedback of lncRNA ANRIL/miRNA‐339‐5p/ZBTB7A Suppresses Metastasis of Nasopharyngeal Carcinoma Cells via SREBP1‐FASN

Cancer Science, EarlyView.
Disruptions in lipid metabolism can hasten disease progression and impose a heavier burden on patients with nasopharyngeal carcinoma (NPC). The ANRIL/miR‐339‐5p/ZBTB7A axis creates a positive feedback loop that suppresses the lipid pathway. Furthermore, the interventions targeting ANRIL‐shZBTB7A and SREBP inhibitors can effectively disrupt lipid ...
Fei Liu, Jiazhang Wei, Suosu Wei, Mingzheng Mo, Jiao Lan, Jingjin Weng, Ruiping Xiao, Cheng Su, Weiming Deng, Yujuan Huang, Bing Li, Min Li, Le Shi, Yuanjun Zhan, Yunhua Peng, Yongli Wang, Fengzhu Tang, Huadong Liu, Shenhong Qu, Jiangang Long   +19 more
wiley   +1 more source