Results 221 to 230 of about 59,286 (281)

A Novel Fetal Intracranial Measurement Contributing to the Differential Diagnosis of Fetal Microcephaly

Journal of Ultrasound in Medicine, Volume 45, Issue 7, Page 1409-1418, July 2026.
Objectives To evaluate the value of the thickness of the frontal lobe (TFL) and foramen magnum‐to‐cranium distance (FCD) for predicting poor neurodevelopmental outcomes in fetuses with a small head circumference (HC). Methods This retrospective observational study included 39 fetuses with HC < −2 standard deviations (SD) and 592 prospectively collected
Xi Du, Rong Zhu, HongJia Li, Ying Zhao, LinLin Wu, Hong Pan, YiNan Ma, XinLin Hou, JunYa Chen   +8 more
wiley   +1 more source

Impact of Genomic Mutations on the Transcriptional Pathways and Tumor Microenvironment Landscape of Localized Early Prostate Cancer

The Prostate, Volume 86, Issue 10, Page 1103-1114, July 2026.
ABSTRACT Background The management of intermediate‐risk early prostate cancer (PCa) is challenging due to the difficulty in distinguishing indolent from aggressive tumors. This study explores the association between genomic alterations and the tumor and its microenvironment (TME) and implications for disease progression. Methods We performed multi‐omic
William Lautert‐Dutra, Camila M. Melo, Luiz P. Chaves, Francisco C. Souza, Vida Talebian, Cheryl Crozier, Mary Anne Quintayo, Linda Liao, Dan Dion, Fabiano P. Saggioro, Felipe S. Avante, Rodolfo B. dos Reis, Jeremy A. Squire, Jane Bayani   +13 more
wiley   +1 more source

Molecular Interplay of PARN and Telomerase: Tail Modifiers and Disease Implications

WIREs RNA, Volume 17, Issue 4, July/August 2026.
Schematic representation of the molecular interplay between PARN, telomerase‐associated, and the involvement of p53 in regulating telomere maintenance and genome stability. The top panel shows how normal PARN levels are involved in regulating p53 levels and balanced telomerase activity through their regulatory interaction with TERC and TERRA, thus ...
Sujitha Felicitus, Shalon Suzanne Pinto, Sai Samanvitha Madagundapalli Ramakrishna, Dechamma Pandyanada Nanjappa, Gunimala Chakraborty, Anirban Chakraborty   +5 more
wiley   +1 more source

P841: Prenatal diagnosis of chromosomal abnormalities using QF-PCR and chromosomal microarray analysis at a single center

Genetics in Medicine Open
Subhas Saha, Inusha Panigrahi, Anupriya Kaur, Neelam Aggarwal, Shifali Gupta, Rashmi Bagga, Priyanka Srivastava   +6 more
doaj   +1 more source

Chromosomal microarray analysis for prenatal diagnosis of uniparental disomy: a retrospective study. [PDF]

Mol Cytogenet
Xu C, Li M, Gu T, Xie F, Zhang Y, Wang D, Peng J.   +6 more
europepmc   +1 more source

A Practical Framework for GT‐Seq Panel Optimization

Molecular Ecology Resources, Volume 26, Issue 5, July 2026.
ABSTRACT Genotyping‐in‐thousands by sequencing (GT‐seq) panels are powerful tools in ecological, evolutionary and conservation genomics, yet the optimization process critical for robust and reproducible genotyping remains poorly formalized. Here, we present an iterative workflow for GT‐seq panel optimization that emphasizes systematic refinement ...
Chandika RG, Caitlin N. Ott‐Conn, Peter T. Euclide, Julie A. Blanchong, Angela Schmoldt, Randy W. DeYoung, Daniel P. Walsh, Wes A. Larson, Emily K. Latch   +8 more
wiley   +1 more source

Prenatal chromosomal microarray analysis in a large Chinese cohort of fetuses with congenital heart defects: a single center study. [PDF]

Orphanet J Rare Dis
Lu Q, Luo L, Zeng B, Luo H, Wang X, Qiu L, Yang Y, Feng C, Zhou J, Hu Y, Huang T, Ma P, Huang T, Xie K, Yuan H, Huang S, Yang B, Zou Y, Liu Y.   +18 more
europepmc   +1 more source

Genome‐wide analysis of DNA methyltransferases in a model extremophyte, Schrenkiella parvula: Transcriptional dynamics during development and under salt stress

Annals of Applied Biology, Volume 189, Issue 1, July 2026.
Classification of DMTs into 4 subfamilies: two METs, three CMTs, three DRMs, and one DNMT2. The cis‐elements are associated with stress‐response, hormonal regulation, light‐response, and development. RNA‐seq analysis revealed differential expression of DMTs under NaCl stress.
Seher Yolcu, Amin Mirshamsi Kakhki, Ahmad Jalilian, Emre Sevindik, Ismail Turkan   +4 more
wiley   +1 more source

Prenatal detection of distal 18p deletion by chromosomal microarray analysis: Three case reports and literature review. [PDF]

Medicine (Baltimore)
Xu T, Yue F, He J, Zhang H, Liu R.
europepmc   +1 more source