Prenatal chromosomal microarray analysis in foetuses with isolated absent or hypoplastic nasal bone. [PDF]
Ann Med, 2022 Shi X, Lu J, Li L, Wei R, Wu J.
europepmc +3 more sources
Prenatal diagnosis of fetuses conceived by assisted reproductive technology by karyotyping and chromosomal microarray analysis. [PDF]
PeerJ, 2023 Guo H +7 more
europepmc +2 more sources
Application of chromosome microarray analysis in prenatal diagnosis [PDF]
BMC Pregnancy and Childbirth, 2020 Abstract Background To explore the application value of chromosomal microarray analysis (CMA) in prenatal diagnosis. Methods The results of chromosome karyotype analysis and CMA of 477 cases undergoing amniocentesis were analyzed. The results of the no ultrasound abnormality group and the ultrasound abnormality group were compared separately.
Mingjing Xia +5 more
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MACAT--microarray chromosome analysis tool [PDF]
Bioinformatics, 2004 By linking differential gene expression to the chromosomal localization of genes, one can investigate microarray data for characteristic patterns of expression phenomena involving sizeable parts of specific chromosomes. We have implemented a statistical approach for identifying significantly differentially expressed chromosome regions.
Matthias Heinig +4 more
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Prenatal diagnosis by chromosomal microarray analysis [PDF]
Fertility and Sterility, 2018 Chromosomal microarray analysis (CMA) is performed either by array comparative genomic hybridization or by using a single nucleotide polymorphism array. In the prenatal setting, CMA is on par with traditional karyotyping for detection of major chromosomal imbalances such as aneuploidy and unbalanced rearrangements.
Brynn Levy, Ronald J. Wapner
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Prenatal diagnosis of chromosomal aberrations by chromosomal microarray analysis in foetuses with ventriculomegaly [PDF]
Scientific Reports, 2020 AbstractVentriculomegaly is considered to be linked to abnormal neurodevelopment outcome. The aim of this retrospective study was to investigate the current applications of chromosomal microarray analysis (CMA) in foetuses with ventriculomegaly. A total of 548 foetuses with ventriculomegaly detected by prenatal ultrasound underwent single nucleotide ...
He Wang +8 more
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Chromosomal mosaicism detected by karyotyping and chromosomal microarray analysis in prenatal diagnosis [PDF]
Journal of Cellular and Molecular Medicine, 2020 AbstractTo investigate the incidence and clinical significance of chromosomal mosaicism (CM) in prenatal diagnosis by G‐banding karyotyping and chromosomal microarray analysis (CMA). This is a single‐centre retrospective study of invasive prenatal diagnosis for CM.
Yi Zhang, Mei Zhong, Dezhong Zheng
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Correction: Chromosomal variants accumulate in genomes of the spontaneous aborted fetuses revealed by chromosomal microarray analysis [PDF]
PLoS ONE, 2022 Sen Li +8 more
doaj +2 more sources
A teratocarcinoma-like human embryonic stem cell (hESC) line and four hESC lines reveal potentially oncogenic genomic changes [PDF]
, 2010 The first Swiss human embryonic stem cell (hESC) line, CH-ES1, has shown features of a malignant cell line. It originated from the only single blastomere that survived cryopreservation of an embryo, and it more closely resembles teratocarcinoma lines ...
Alexis Bosman +15 more
core +15 more sources
A new direction for prenatal chromosome microarray testing: software-targeting for detection of clinically significant chromosome imbalance without equivocal findings [PDF]
PeerJ, 2014 Purpose. To design and validate a prenatal chromosomal microarray testing strategy that moves away from size-based detection thresholds, towards a more clinically relevant analysis, providing higher resolution than G-banded chromosomes but avoiding the ...
Joo Wook Ahn +6 more
doaj +2 more sources