The enigma of the B chromosome-specific behaviour. [PDF]
Hloušková L +2 more
europepmc +1 more source
TaHDA1‐mediated histone and non‐histone deacetylation orchestrates drought tolerance in wheat
The histone deacetylase TaHDA1 is a key regulator linking histone and non‐histone deacetylation with drought adaptation and a potential target for improving drought resilience and grain nutritional quality in wheat. ABSTRACT Drought stress severely constrains wheat (Triticum aestivum L.) growth and productivity.
Jinpeng Li +21 more
wiley +1 more source
Mega-enhancers compartmentalize transcriptionally active long genes in the brain. [PDF]
Zhao Z +7 more
europepmc +1 more source
SlBPC1 regulates fruit elongation by directly repressing SlOFP2/SlOFP21 and SUN expression in tomato
In tomato, switching off the transcription factor gene SlBPC1 leads to longer fruits by altering cell division patterns during early fruit development. The SlBPC1 regulatory pathway includes the SlOFP2, SlOFP21, and SUN genes, offering valuable targets for breeding tomatoes with market‐preferred shapes.
Sunan Gao +14 more
wiley +1 more source
BRIP1, a G-quadruplex DNA helicase, protects against AID-induced genomic instability by limiting R-loop accumulation. [PDF]
Mahboob A +4 more
europepmc +1 more source
20th Anniversary of human‐induced pluripotent stem cells and the role of microscopy
Abstract It has been 20 years since the pioneering work of Shinya Yamanaka and Kazutoshi Takahashi at Kyoto University led to the first successful generation of induced pluripotent stem cells (iPSCs) from mouse embryonic and adult fibroblast cells. iPSCs have the capacity to differentiate into any type of cell in the human body, and as such, they have ...
Philomena Hallford +3 more
wiley +1 more source
Probing Centromere Plasticity and Chromatin Remodeling Using Single-Molecule Techniques. [PDF]
Liu R, Zhao J, Ma H, Hu W, Dou Z, Liu X.
europepmc +1 more source
A well‐preserved 20 post‐conception week human brain was obtained and finely dissected into 18 anatomically distinct regions, including the pia mater. Each region underwent in‐depth proteomic analysis, encompassing both total protein content and post‐translational modifications.
S. Bandiera +9 more
wiley +1 more source
Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities. [PDF]
Pal A, Patra M, Mondal R, Haldar S.
europepmc +1 more source
Epigenetic Regulation in the Pathogenesis of Periodontitis
The aim of this narrative literature review was to identify epigenetic marks associated with periodontitis and to place them in a biological context. The literature was reviewed based on pre‐defined criteria. Cell type specific chromatin and mRNA modifications were included.
Henrik Dommisch +3 more
wiley +1 more source

