Results 41 to 50 of about 67,196 (148)

3D chromatin maps of a brown alga reveal U/V sex chromosome spatial organization

Nature Communications
Nuclear three dimensional (3D) folding of chromatin structure has been linked to gene expression regulation and correct developmental programs, but little is known about the 3D architecture of sex chromosomes within the nucleus, and how that impacts ...
Pengfei Liu, Jeromine Vigneau, Rory J. Craig, Josué Barrera-Redondo, Elena Avdievich, Claudia Martinho, Michael Borg, Fabian B. Haas, Chang Liu, Susana M. Coelho   +9 more
doaj   +1 more source

Effect of irinotecan on HMGB1, MMP9 expression, cell cycle, and cell growth in breast cancer (MCF-7) cells

Tumor Biology, 2017
Irinotecan is a natural alkaloid agent widely used in cancer therapy. High-mobility group protein B1 as a non-histone chromosomal protein plays a fundamental role in gene expression and inflammation.
Saeedeh Keyvani-Ghamsari, Azra Rabbani-Chadegani, Javad Sargolzaei, Maryam Shahhoseini   +3 more
doaj   +1 more source

Characterizing the DNA Damage Response by Cell Tracking Algorithms and Cell Features Classification Using High-Content Time-Lapse Analysis.

PLoS ONE, 2015
Traditionally, the kinetics of DNA repair have been estimated using immunocytochemistry by labeling proteins involved in the DNA damage response (DDR) with fluorescent markers in a fixed cell assay.
Walter Georgescu, Alma Osseiran, Maria Rojec, Yueyong Liu, Maxime Bombrun, Jonathan Tang, Sylvain V Costes   +6 more
doaj   +1 more source

Microheterogeneity in a non‐histone chromosomal protein [PDF]

FEBS Letters, 1976
Goodwin, Graham H., Nicolas, Robert H., Johns, Ernest W.   +2 more
openaire   +2 more sources

Crystal structure of the HMGA AT-hook 1 domain bound to the minor groove of AT-rich DNA and inhibition by antikinetoplastid drugs

Scientific Reports
High mobility group (HMG) proteins are intrinsically disordered nuclear non-histone chromosomal proteins that play an essential role in many biological processes by regulating the expression of numerous genes in eukaryote cells.
J. Jonathan Nué-Martinez, Marta Maturana, Laura Lagartera, Juan-Antonio Rodríguez-Gutiérrez, Roeland Boer, J. Lourdes Campos, Núria Saperas, Christophe Dardonville   +7 more
doaj   +1 more source

Tissue-specific chromosomal non-histone protein interactions with DNA.

Journal of Biological Chemistry, 1976
A group of chromosomal non-histone proteins with affinity for DNA (NP) was isolated from rat liver and Novikoff hepatoma. This fraction, which represents less than 5% of the total chromatin protein content, binds preferentially to unique, double-stranded sequences of fractionated homologous DNA. The interactions are strong at low ionic strength (Km = 6.
S, Wang, J F, Chiu, L, Klyszejko-Stefanowicz, H, Fujitani, L S, Hnilica   +4 more
openaire   +2 more sources

Transgenic plants as a model for studying еpigenetic regulation of gene expression

Вавиловский журнал генетики и селекции, 2015
The phenomenon of loss of expression of transferred genes in transgenic plants was discovered in the early 1990s. The study of this phenomenon revealed dependence of the frequency of gene silencing on the number of integrated copies in the plant genome ...
T. V. Marenkova, E. V. Deineko
doaj  

Low levels of non‐histone chromosomal proteins in trout testis chromatin [PDF]

FEBS Letters, 1976
Candido, E.P.M., Honda, B.M., Baillie, D.L.   +2 more
openaire   +2 more sources

Non-Histone Chromosomal Protein HMG-17 [PDF]

, 2020
openaire   +1 more source

Trout liver high mobility group non‐histone chromosomal proteins [PDF]

FEBS Letters, 1980
Rabbani, Azra, Goodwin, Graham H., Walker, John M., Brown, Elizabeth, Johns, Ernest W.   +4 more
openaire   +2 more sources