Results 21 to 30 of about 12,009,217 (285)

Phosphorylation of SU(VAR)3-9 by the chromosomal kinase JIL-1 [PDF]

, 2010
The histone methyltransferase SU(VAR)3-9 plays an important role in the formation of heterochromatin within the eukaryotic nucleus. Several studies have shown that the formation of condensed chromatin is highly regulated during development, suggesting ...
Johansen Kristen M., Boeke, Joern, Regnard Catherine, Peter B Becker, Kristen M Johansen, Weili Cai, Becker Peter B., Boeke Joern, Johansen Jørgen, Imhof Axel, Regnard, Catherine, Cai, Weili, Johansen, Jørgen, Imhof, Axel, Becker, Peter B., Joern Boeke, Johansen, Kristen M, Catherine Regnard, Axel Imhof, Jørgen Johansen, Cai Weili   +20 more
core   +2 more sources

Selfish chromosomal drive shapes recent centromeric histone evolution in monkeyflowers.

PLoS Genetics, 2021
Centromeres are essential mediators of chromosomal segregation, but both centromeric DNA sequences and associated kinetochore proteins are paradoxically diverse across species.
Findley R Finseth, Thomas C Nelson, Lila Fishman   +2 more
doaj   +1 more source

Depletion of Uhrf1 inhibits chromosomal DNA replication in Xenopus egg extracts [PDF]

, 2013
UHRF1 (ubiquitin-like, containing PHD and RING finger domains 1) has a well-established role in epigenetic regulation through the recognition of various histone marks and interaction with chromatin-modifying proteins.
Taylor, Elaine, Price, Jordan, Bonsu-Dartnall, Nicola, Lindsay, Howard   +3 more
core   +4 more sources

Compositional and structural analysis of selected chromosomal domains from Saccharomyces cerevisiae [PDF]

, 2012
In eukaryotic genomes, chromatin is the template of all nuclear processes including transcription, recombination and replication. Besides the wrapping of DNA in nucleosome core particles, eukaryotic chromatin is associated, interpreted and modified by ...
Hamperl, Stephan
core   +1 more source

Versatile toolbox for high throughput biochemical and functional studies with fluorescent fusion proteins [PDF]

, 2012
Fluorescent fusion proteins are widely used to study protein localization and interaction dynamics in living cells. However, to fully characterize proteins and to understand their function it is crucial to determine biochemical characteristics such as ...
Sandra B. Hake (165089), Antonia Jack (165084), Sandra B Hake, Patricia Wolf, Pichler Garwin, Pichler, Garwin, Hake, Sandra B., Antonia Jack, Wolf Patricia, Garwin Pichler (165082), Jack Antonia, Wolf, Patricia, Jack, Antonia, Hake Sandra B., Garwin Pichler, Patricia Wolf (165088)   +15 more
core   +2 more sources

Spt2p defines a new transcription-dependent gross chromosomal rearrangement pathway.

PLoS Genetics, 2008
Large numbers of gross chromosomal rearrangements (GCRs) are frequently observed in many cancers. High mobility group 1 (HMG1) protein is a non-histone DNA-binding protein and is highly expressed in different types of tumors.
Nilabja Sikdar, Soma Banerjee, Han Zhang, Stephanie Smith, Kyungjae Myung   +4 more
doaj   +1 more source

The histone chaperones Nap1 and Vps75 bind histones H3 and H4 in a tetrameric conformation [PDF]

, 2011
Histone chaperones physically interact with histones to direct proper assembly and disassembly of nucleosomes regulating diverse nuclear processes such as DNA replication, promoter remodeling, transcription elongation, DNA damage, and histone variant ...
Bowman, Andrew, El Mkami, Hassane, Nicola Wiechens, Bowman, A., Vijender Singh, Andrew Bowman, David George Norman, Ward, Richard, Singh, Vijender, Owen-Hughes, Tom; id_orcid, El-Mkami, Hassane, Richard Ward, Hassane El-Mkami, Wiechens, Nicola, Norman, David George, Owen-Hughes, Tom, Tom Owen-Hughes, El Mkami, Hassane; id_orcid   +17 more
core   +1 more source

c-Myc-Induced Extrachromosomal Elements Carry Active Chromatin

Neoplasia: An International Journal for Oncology Research, 2003
Murine Pre-13 lymphocytes with experimentally activated MycER show both chromosomal and extrachromosomal gene amplification. In this report, we have elucidated the size, structure, functional components of c-Myc-induced extrachromosomal elements (EEs ...
Greg Smith, Cheryl Taylor-Kashton, Len Dushnicky, Stephen Symons, Jim Wright, Sabine Mai   +5 more
doaj   +1 more source

CenH3 distribution reveals extended centromeres in the model beetle Tribolium castaneum.

PLoS Genetics, 2020
Centromeres are chromosomal domains essential for kinetochore assembly and correct chromosome segregation. Inconsistent in their underlying DNA sequences, centromeres are defined epigenetically by the presence of the centromere-specific histone H3 ...
Tena Gržan, Evelin Despot-Slade, Nevenka Meštrović, Miroslav Plohl, Brankica Mravinac   +4 more
doaj   +1 more source

Sequence-specific targeting of dosage compensation in Drosophila favors an active chromatin context. [PDF]

PLoS Genetics, 2012
The Drosophila MSL complex mediates dosage compensation by increasing transcription of the single X chromosome in males approximately two-fold. This is accomplished through recognition of the X chromosome and subsequent acetylation of histone H4K16 on X ...
Artyom A Alekseyenko, Joshua W K Ho, Shouyong Peng, Marnie Gelbart, Michael Y Tolstorukov, Annette Plachetka, Peter V Kharchenko, Youngsook L Jung, Andrey A Gorchakov, Erica Larschan, Tingting Gu, Aki Minoda, Nicole C Riddle, Yuri B Schwartz, Sarah C R Elgin, Gary H Karpen, Vincenzo Pirrotta, Mitzi I Kuroda, Peter J Park   +18 more
doaj   +1 more source