Results 21 to 30 of about 67,067 (247)

c-Myc-Induced Extrachromosomal Elements Carry Active Chromatin

open access: yesNeoplasia: An International Journal for Oncology Research, 2003
Murine Pre-13 lymphocytes with experimentally activated MycER show both chromosomal and extrachromosomal gene amplification. In this report, we have elucidated the size, structure, functional components of c-Myc-induced extrachromosomal elements (EEs ...
Greg Smith   +5 more
doaj   +1 more source

Mouse non-histone chromosomal protein HMG-17 cDNA sequence

open access: yesNucleic Acids Research, 1988
David Landsman   +2 more
exaly   +4 more sources

CenH3 distribution reveals extended centromeres in the model beetle Tribolium castaneum.

open access: yesPLoS Genetics, 2020
Centromeres are chromosomal domains essential for kinetochore assembly and correct chromosome segregation. Inconsistent in their underlying DNA sequences, centromeres are defined epigenetically by the presence of the centromere-specific histone H3 ...
Tena Gržan   +4 more
doaj   +1 more source

Sequence-specific targeting of dosage compensation in Drosophila favors an active chromatin context. [PDF]

open access: yesPLoS Genetics, 2012
The Drosophila MSL complex mediates dosage compensation by increasing transcription of the single X chromosome in males approximately two-fold. This is accomplished through recognition of the X chromosome and subsequent acetylation of histone H4K16 on X ...
Artyom A Alekseyenko   +18 more
doaj   +1 more source

DNA Modifications: Function and Applications in Normal and Disease States

open access: yesBiology, 2014
Epigenetics refers to a variety of processes that have heritable effects on gene expression programs without changes in DNA sequence. Key players in epigenetic control are chemical modifications to DNA, histone, and non-histone chromosomal proteins ...
Vichithra R. B. Liyanage   +5 more
doaj   +1 more source

Epigenetics and airways disease

open access: yesRespiratory Research, 2006
Epigenetics is the term used to describe heritable changes in gene expression that are not coded in the DNA sequence itself but by post-translational modifications in DNA and histone proteins. These modifications include histone acetylation, methylation,
Ito Kazuhiro   +3 more
doaj   +1 more source

The Methylation Status of DNA in Hepatocellular Carcinoma [PDF]

open access: yesMinia Journal of Medical Research, 2019
The most common cause of cancer liver is hepatocellular carcinoma (HCC) and it is an important cause of cancer-related death all over the world (Crissien and Frenette, 2014).
Mostafa Mourad   +4 more
doaj   +1 more source

HMGA2, the architectural transcription factor high mobility group, is expressed in the developing and mature mouse cochlea. [PDF]

open access: yesPLoS ONE, 2014
Hmga2 protein belongs to the non-histone chromosomal high-mobility group (HMG) protein family. HMG proteins have been shown to function as architectural transcription regulators, facilitating enhanceosome formation on a variety of mammalian promoters ...
Ibtihel Smeti   +4 more
doaj   +1 more source

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