Results 1 to 10 of about 7,557 (223)
Commentary on Tawar, R.G.; Duquerroy, S.; Vonrhein, C.; Varela, P.F.; Damier-Piolle, L.; Castagné, N.; MacLellan, K.; Bedouelle, H.; Bricogne, G.; Bhella, D.; Eléouët, J.-F.; Rey, F.A. Crystal structure of a nucleocapsid-like nucleoprotein-RNA complex of
Thibaut Crépin, Rob W. H. Ruigrok
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A universal SARS‐CoV DNA vaccine inducing highly cross‐reactive neutralizing antibodies and T cells
New variants in the SARS‐CoV‐2 pandemic are more contagious (Alpha/Delta), evade neutralizing antibodies (Beta), or both (Omicron). This poses a challenge in vaccine development according to WHO.
Sofia Appelberg +19 more
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Flexible filamentous viruses include economically important plant pathogens. Their viral particles contain several hundred copies of a helically arrayed coat protein (CP) protecting a (+)ssRNA.
Xabier Agirrezabala +5 more
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The Nucleocapsid of Paramyxoviruses: Structure and Function of an Encapsidated Template
Viruses of the Paramyxoviridae family share a common and complex molecular machinery for transcribing and replicating their genomes. Their non-segmented, negative-strand RNA genome is encased in a tight homopolymer of viral nucleoproteins (N).
Louis-Marie Bloyet
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NUCLEAR LOCALIZATION SIGNAL PEPTIDES (NLS) AND THEIR ROLE IN VIRAL PATHOGENICITY
The review provides data about nuclear localization signal peptides (NLS) and their function in the cell, incl. with a viral infection process. The binding, penetration, assembly, and budding of viruses are currently being intensively studied in many ...
Nosalskaya, Tatiana Nikolaevna +2 more
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Structural comparisons of the nucleoprotein from three negative strand RNA virus families
Structures of the nucleoprotein of three negative strand RNA virus families, borna disease virus, rhabdovirus and influenza A virus, are now available. Structural comparisons showed that the topology of the RNA binding region from the three proteins is ...
Tsao Jun +4 more
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Efficient soluble expression and purification of influenza A and B nucleoproteins in E. coli
Viral nucleoprotein (NP) is an abundant essential protein of an influenza virus that has important functional and structural roles. It participates in genomic organization, nuclear trafficking, RNA transcription, and genome replication. From the research
Nikita D. Yolshin +2 more
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Background: The study aimed to detect the association between insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) and interleukin-6 (IL-6) polymorphisms among type 2 diabetes mellitus (T2DM).
Elmutuz H Elssaig +4 more
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Schisandra chinensis (Turcz.) Baill. polysaccharide inhibits influenza A virus in vitro and in vivo
Influenza virus is prone to seasonal spread and widespread outbreaks, which pose important challenges to public health security. Therefore, it is important to effectively prevent and treat influenza virus infection.
Jing Qi +9 more
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Rift Valley fever virus detection in susceptible hosts with special emphasis in insects
Rift Valley fever phlebovirus (RVFV, Phenuiviridae) is an emerging arbovirus that can cause potentially fatal disease in many host species including ruminants and humans.
K. M. Gregor +19 more
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