Results 1 to 10 of about 25,304 (272)

Differential Behaviours and Preferential Bindings of Influenza Nucleoproteins on Importins-α

Viruses, 2020
Influenza viruses are negative single-stranded RNA viruses with nuclear transcription and replication. They enter the nucleus by using the cellular importin-α/-β nuclear import machinery.
Amélie Donchet, Emilie Vassal-Stermann, Francine C. A. Gérard, Rob W. H. Ruigrok, Thibaut Crépin   +4 more
doaj   +2 more sources

Novel Bunyavirus in Domestic and Captive Farmed Animals, Minnesota, USA

Emerging Infectious Diseases, 2013
We tested blood samples from domestic and captive farmed animals in Minnesota, USA, to determine exposure to severe fever with thrombocytopenia syndrome virus and Heartland-like virus.
Zheng Xing, Jeremy Schefers, Marc Schwabenlander, Yongjun Jiao, Mifang Liang, Xian Qi, Chuan Li, Sagar Goyal, Carol J. Cardona, Xiaodong Wu, Zerui Zhang, Dexin Li, James Collins, Michael P. Murtaugh   +13 more
doaj   +1 more source

Structural disorder within paramyxoviral nucleoproteins

FEBS Letters, 2015
In this review I summarize available data pointing to the abundance of structural disorder within the nucleoprotein (N) from three paramyxoviruses, namely the measles (MeV), Nipah (NiV) and Hendra (HeV) viruses.
S. Longhi
semanticscholar   +1 more source

Lipids contribute to epigenetic control via chromatin structure and functions

ScienceOpen Research, 2016
Isolated cases of experimental evidence over the last few decades have shown that, where specifically tested, both prokaryotes and eukaryotes have specific lipid species bound to nucleoproteins of the genome. In vitro, some of these lipid species exhibit
Renad Zhdanov, Eric Schirmer, Anuroop Venkateswaran Venkatasubramani, Alastair Kerr, Elena Mandrou, Giovanny Rodriguez Blanco, Alexander Kagansky   +6 more
doaj   +1 more source

Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression

Journal of Biological Chemistry, 2013
Background: Arenaviral nucleoproteins play a critical role in innate immune suppression. Results: Structures of Lassa nucleoprotein in complex with triphosphate dsRNA and Tacaribe virus nucleoprotein have been determined.
Xue Jiang, Qinfeng Huang, Wenjian Wang, Haohao Dong, H. Ly, Yu-Ying Liang, C. Dong   +6 more
semanticscholar   +1 more source

BUFFER SYSTEMS OF THE BODY

Актуальные проблемы теоретической и клинической медицины, 2022
A large number of acidic foods is formed in the human body during the metabolism during the day. The main products of metabolism in the cell are acids that dissociate with the release of [H+] ions, but due to buffer systems, acidification of the ...
N. V. Leontyeva
doaj   +1 more source

Distinctive Nuclear Features of Dinoflagellates with A Particular Focus on Histone and Histone-Replacement Proteins

Microorganisms, 2018
Dinoflagellates are important eukaryotic microorganisms that play critical roles as producers and grazers, and cause harmful algal blooms. The unusual nuclei of dinoflagellates “dinokaryon„ have led researchers to investigate their enigmatic ...
Sadaf Riaz, Zhenghong Sui, Zeeshan Niaz, Sohrab Khan, Yuan Liu, Haoxin Liu   +5 more
doaj   +1 more source

m6 RNA methylation: an emerging common target in the immune response to cancer and severe acute respiratory syndrome-coronavirus-2 infection

Exploration of Medicine, 2023
m6A RNA methylation, a predominant type of RNA modification, is involved in regulating mRNA splicing, stability, and translation as well as the interaction between nucleoproteins and noncoding RNAs.
Hiromichi Sato, Tomoaki Hara, Chihiro Otsuka, Yasuko Arao, Yoshiko Tsuji, Yumiko Hamano, Mirei Ogita, Eric di Luccio, Takaaki Hirotsu, Andrea Vecchione, Hideshi Ishii   +10 more
doaj   +1 more source

Multivalent Pseudopeptides Targeting Cell Surface Nucleoproteins Inhibit Cancer Cell Invasion through Tissue Inhibitor of Metalloproteinases 3 (TIMP-3) Release*

Journal of Biological Chemistry, 2012
Background: NucAnt 6L (N6L) binds to nucleoproteins and inhibits tumor growth. Results: N6L bound to sulfated glycosaminoglycans, induced TIMP-3 release, and inhibited cell invasion. Silencing of TIMP-3 abolished N6L effect on cell invasion.
Damien Destouches, E. Huet, Maha Sader, Sophie Fréchault, G. Carpentier, Florie Ayoul, J. Briand, S. Ménashi, J. Courty   +8 more
semanticscholar   +1 more source

Viral proteins as a potential driver of histone depletion in dinoflagellates

Nature Communications, 2018
Dinoflagellates are known to use dinoflagellate-viral-nucleoproteins (DVNPs) in place of histones, yet this evolutionary transition is not well understood. Here, Irwin et al. use yeast expressing DVNP to show that DVNP displaces histones and that histone
Nicholas A. T. Irwin, Benjamin J. E. Martin, Barry P. Young, Martin J. G. Browne, Andrew Flaus, Christopher J. R. Loewen, Patrick J. Keeling, LeAnn J. Howe   +7 more
doaj   +1 more source