Results 1 to 10 of about 7,557 (223)

Nucleoproteins of Negative Strand RNA Viruses; RNA Binding, Oligomerisation and Binding to Polymerase Co-Factor

open access: yesViruses, 2010
Commentary on Tawar, R.G.; Duquerroy, S.; Vonrhein, C.; Varela, P.F.; Damier-Piolle, L.; Castagné, N.; MacLellan, K.; Bedouelle, H.; Bricogne, G.; Bhella, D.; Eléouët, J.-F.; Rey, F.A. Crystal structure of a nucleocapsid-like nucleoprotein-RNA complex of
Thibaut Crépin, Rob W. H. Ruigrok
doaj   +1 more source

A universal SARS‐CoV DNA vaccine inducing highly cross‐reactive neutralizing antibodies and T cells

open access: yesEMBO Molecular Medicine, 2022
New variants in the SARS‐CoV‐2 pandemic are more contagious (Alpha/Delta), evade neutralizing antibodies (Beta), or both (Omicron). This poses a challenge in vaccine development according to WHO.
Sofia Appelberg   +19 more
doaj   +1 more source

The near-atomic cryoEM structure of a flexible filamentous plant virus shows homology of its coat protein with nucleoproteins of animal viruses

open access: yeseLife, 2015
Flexible filamentous viruses include economically important plant pathogens. Their viral particles contain several hundred copies of a helically arrayed coat protein (CP) protecting a (+)ssRNA.
Xabier Agirrezabala   +5 more
doaj   +1 more source

The Nucleocapsid of Paramyxoviruses: Structure and Function of an Encapsidated Template

open access: yesViruses, 2021
Viruses of the Paramyxoviridae family share a common and complex molecular machinery for transcribing and replicating their genomes. Their non-segmented, negative-strand RNA genome is encased in a tight homopolymer of viral nucleoproteins (N).
Louis-Marie Bloyet
doaj   +1 more source

NUCLEAR LOCALIZATION SIGNAL PEPTIDES (NLS) AND THEIR ROLE IN VIRAL PATHOGENICITY

open access: yesAnnals of Mechnikov's Institute, 2020
The review provides data about nuclear localization signal peptides (NLS) and their function in the cell, incl. with a viral infection process. The binding, penetration, assembly, and budding of viruses are currently being intensively studied in many ...
Nosalskaya, Tatiana Nikolaevna   +2 more
doaj   +3 more sources

Structural comparisons of the nucleoprotein from three negative strand RNA virus families

open access: yesVirology Journal, 2007
Structures of the nucleoprotein of three negative strand RNA virus families, borna disease virus, rhabdovirus and influenza A virus, are now available. Structural comparisons showed that the topology of the RNA binding region from the three proteins is ...
Tsao Jun   +4 more
doaj   +1 more source

Efficient soluble expression and purification of influenza A and B nucleoproteins in E. coli

open access: yesMicrobiology Independent Research Journal, 2019
Viral nucleoprotein (NP) is an abundant essential protein of an influenza virus that has important functional and structural roles. It participates in genomic organization, nuclear trafficking, RNA transcription, and genome replication. From the research
Nikita D. Yolshin   +2 more
doaj   +1 more source

Significant association between insulin-like growth factor 2 mRNA-binding protein 2, interleukin-6 polymorphisms, and type 2 diabetes mellitus

open access: yesJournal of Research in Medical Sciences
Background: The study aimed to detect the association between insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) and interleukin-6 (IL-6) polymorphisms among type 2 diabetes mellitus (T2DM).
Elmutuz H Elssaig   +4 more
doaj   +1 more source

Schisandra chinensis (Turcz.) Baill. polysaccharide inhibits influenza A virus in vitro and in vivo

open access: yesFEBS Open Bio, 2023
Influenza virus is prone to seasonal spread and widespread outbreaks, which pose important challenges to public health security. Therefore, it is important to effectively prevent and treat influenza virus infection.
Jing Qi   +9 more
doaj   +1 more source

Rift Valley fever virus detection in susceptible hosts with special emphasis in insects

open access: yesScientific Reports, 2021
Rift Valley fever phlebovirus (RVFV, Phenuiviridae) is an emerging arbovirus that can cause potentially fatal disease in many host species including ruminants and humans.
K. M. Gregor   +19 more
doaj   +1 more source

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