Comparative Production Analysis of Three Phlebovirus Nucleoproteins under Denaturing or Non-Denaturing Conditions for Crystallographic Studies [PDF]
Nucleoproteins (NPs) encapsidate the Phlebovirus genomic (-)RNA. Upon recombinant expression, NPs tend to form heterogeneous oligomers impeding characterization of the encapsidation process through crystallographic studies.
Rémi N Charrel +2 more
exaly +3 more sources
Identification and characterization of codon usage pattern and influencing factors in HFRS-causing hantaviruses. [PDF]
Hemorrhagic fever with renal syndrome (HFRS) is an acute viral zoonosis carried and transmitted by infected rodents through urine, droppings, or saliva.
Noor F +7 more
europepmc +2 more sources
Mitochondrial nucleoproteins in rye leaves
Some properties of mitochondrial nucleoproteins sedimentable at 100 000 g, corresponding to the hyaloplasmic ribosomes, were compared with those found for two other subfractions isolated from mitochondria of primary rye (Secale cereale) leaves, the ...
M. Rytel +2 more
doaj +2 more sources
Comprehensive computational analysis reveals YXXΦ[I/L/M/F/V] motif and YXXΦ-like tetrapeptides across HFRS causing Hantaviruses and their association with viral pathogenesis and host immune regulation. [PDF]
Hemorrhagic fever with renal syndrome (HFRS) is an acute zoonotic disease transmitted through aerosolized excrement of rodents. The etiology of HFRS is complex due to the involvement of viral factors and host immune and genetic factors. The viral species
Noor F +5 more
europepmc +2 more sources
Serological Evidence of Hantavirus in Bats from the Brazilian Atlantic Forest: An Investigation of Seroreactivity and Cross-Reactivity of Neotropical Bat Samples Using Nucleoproteins of Rodent- and Bat-Borne Hantaviruses. [PDF]
Hantaviruses are zoonotic pathogens associated with severe human diseases such as hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome.
Rangel CL +13 more
europepmc +2 more sources
Differential Behaviours and Preferential Bindings of Influenza Nucleoproteins on Importins-α
Influenza viruses are negative single-stranded RNA viruses with nuclear transcription and replication. They enter the nucleus by using the cellular importin-α/-β nuclear import machinery.
Amélie Donchet +4 more
doaj +2 more sources
Structural Homology Between Nucleoproteins of ssRNA Viruses
Our understanding of the viral world changed just after the first structures of icosahedral viral particles were unveiled. The structural similarities between capsid proteins of distant viral groups were not anticipated, and the findings suggested the ...
Mikel Valle, Valle Mikel
exaly +2 more sources
Immunomodulatory properties of morbillivirus nucleoproteins.
International audienceMorbillivirus infections have been known for a long time to be associated with an acute immunosuppression in their natural hosts.
Kerdiles, Yann, +25 more
core +6 more sources
Revealing long-range heterogeneous organization of nucleoproteins with 6mA footprinting by ipdTrimming. [PDF]
Enabled by long-read sequencing technologies, particularly Single Molecule, Real-Time sequencing, N6-methyladenine (6mA) footprinting is a transformative methodology for revealing the heterogenous and dynamic distribution of nucleosomes and other DNA ...
Yang W +5 more
europepmc +2 more sources
ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication. [PDF]
Nucleoproteins (N) of negative‐sense RNA viruses exhibit an inherent tendency to oligomerize, forming a ribonucleoprotein complex that protects the viral genome.
Zhou H +8 more
europepmc +2 more sources

