Results 31 to 40 of about 7,536 (222)
Crystal structure of Schmallenberg orthobunyavirus nucleoprotein-RNA complex reveals a novel RNA sequestration mechanism [PDF]
, 2013 Schmallenberg virus (SBV) is a newly emerged orthobunyavirus (family Bunyaviridae) that has caused severe disease in the offspring of farm animals across Europe.
Richard M. Elliott +16 more
core +1 more source
, 2023 Collection of data used to explore the variation in the number of dissociable amino acids in the spike proteins and nucleoproteins of SARS-CoV-2 variants as well as in other ...
Anže Božič, Rudolf Podgornik
core +1 more source
Viral proteins as a potential driver of histone depletion in dinoflagellates
Nature Communications, 2018 Dinoflagellates are known to use dinoflagellate-viral-nucleoproteins (DVNPs) in place of histones, yet this evolutionary transition is not well understood. Here, Irwin et al. use yeast expressing DVNP to show that DVNP displaces histones and that histone
Nicholas A. T. Irwin +7 more
doaj +1 more source
Structural landscape of the respiratory syncytial virus nucleocapsids
Nature Communications, 2023 Human Respiratory Syncytial Virus (HRSV) is a prevalent cause of severe respiratory infections in children and the elderly. The helical HRSV nucleocapsid is a template for the viral RNA synthesis and a scaffold for the virion assembly. This cryo-electron
Lorène Gonnin +6 more
doaj +1 more source
, 2014 Zusammenfassend läßt sich sagen, daß im menschlichen Serum ein Serumprotein vorhanden ist, welches das aus menschlichem Gewebe gewonnene Nucleoprotein spezifisch bindet. Zur Zeit sind Untersuchungen im Gang.
Wilhelm, Günther
core +2 more sources
Systemic Lupus Erythematosus and DNA Degradation and Elimination Defects
Frontiers in Immunology, 2019 Introduction: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that is characterized by the production of autoantibodies specific for components of the cell nucleus and that causes damage to body tissues and organs.
Borros Arneth
doaj +1 more source
Cellular Factors Involved in the Hepatitis D Virus Life Cycle
Viruses, 2023 Hepatitis D virus (HDV) is a defective RNA virus with a negative-strand RNA genome encompassing less than 1700 nucleotides. The HDV genome encodes only for one protein, the hepatitis delta antigen (HDAg), which exists in two forms acting as ...
Keerthihan Thiyagarajah +2 more
doaj +1 more source
Angewandte Chemie, EarlyView.Rationally designed DNA multivalent aptamers direct specific protein binding to drive self‐assembly into protein‐DNA frameworks (PDFs). Structurally defined protein‐aptamer interfaces organize proteins into triangles, linear and ladderlike chains, and periodic two‐dimensional arrays, enabling precise control over orientation, connectivity, and overall ...
Zhe Zhang +11 more
wiley +2 more sources
Intracellular Crosslinking of Filoviral Nucleoproteins with Xintrabodies Restricts Viral Packaging
Frontiers in Immunology, 2017 Viruses assemble large macromolecular repeat structures that become part of the infectious particles or virions. Ribonucleocapsids (RNCs) of negative strand RNA viruses are a prime example where repetition of nucleoprotein (NP) along the genome creates a
Tamarand Lee Darling +3 more
doaj +1 more source
Monomeric Nucleoprotein of Influenza A Virus
PLoS Pathogens, 2013 Isolated influenza A virus nucleoprotein exists in an equilibrium between monomers and trimers. Samples containing only monomers or only trimers can be stabilized by respectively low and high salt. The trimers bind RNA with high affinity but remain trimmers, whereas the monomers polymerise onto RNA forming nucleoprotein-RNA complexes.
Chenavas, Sylvie +8 more
openaire +9 more sources