Results 51 to 60 of about 7,557 (223)

Systemic Lupus Erythematosus and DNA Degradation and Elimination Defects

open access: yesFrontiers in Immunology, 2019
Introduction: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that is characterized by the production of autoantibodies specific for components of the cell nucleus and that causes damage to body tissues and organs.
Borros Arneth
doaj   +1 more source

Über ein aus menschlichen und tierischen Geweben isoliertes Nucleoprotein mit Kollagen-fällenden Eigenschaften. I. Abtrennung und Charakterisierung des Nucleoproteins [PDF]

open access: yes, 1966
Es wird über ein neu aufgefundenes Ribonucleoprotein berichtet, das beim Menschen, Kalb, Ratte und Huhn aus allen untersuchten Organen zu isolieren war.
Wilhelm, G.
core   +1 more source

Cellular Factors Involved in the Hepatitis D Virus Life Cycle

open access: yesViruses, 2023
Hepatitis D virus (HDV) is a defective RNA virus with a negative-strand RNA genome encompassing less than 1700 nucleotides. The HDV genome encodes only for one protein, the hepatitis delta antigen (HDAg), which exists in two forms acting as ...
Keerthihan Thiyagarajah   +2 more
doaj   +1 more source

How order and disorder within paramyxoviral nucleoproteins and phosphoproteins orchestrate the molecular interplay of transcription and replication [PDF]

open access: yes, 2017
International audienceIn this review, we summarize computational and experimental data gathered so far showing that structural disorder is abundant within paramyxoviral nucleoproteins (N) and phosphoproteins (P). In particular, we focus on measles, Nipah,
Longhi, Sonia   +7 more
core   +3 more sources

Monomeric Nucleoprotein of Influenza A Virus

open access: yesPLoS Pathogens, 2013
Isolated influenza A virus nucleoprotein exists in an equilibrium between monomers and trimers. Samples containing only monomers or only trimers can be stabilized by respectively low and high salt. The trimers bind RNA with high affinity but remain trimmers, whereas the monomers polymerise onto RNA forming nucleoprotein-RNA complexes.
Chenavas, Sylvie   +8 more
openaire   +9 more sources

Native morphology of influenza virions

open access: yesFrontiers in Microbiology, 2012
Influenza A virus is an enveloped virus with a segmented, single-strand, negative-sense RNA genome. Its virions show spherical or filamentous shapes of about 100 nm in diameter and occasionally irregular morphology, which exemplifies the pleomorphic ...
Takeshi eNoda
doaj   +1 more source

STAINING OF BASIC NUCLEOPROTEINS BY AN EXTRACT OF THE BLACK RASPBERRY [PDF]

open access: yes, 1974
Methanolic extracts of the black raspberry (Rubrus occidentalis) were found to stain nuclei of normal human peripheral blood and bone marrow cells. Using filter paper spot tests, staining of both purified deoxyribonucleic acid and histone occurred at pH
LAWRENCE KASS
core   +1 more source

Controllable self-replicating RNA vaccine delivered intradermally elicits predominantly cellular immunity

open access: yesiScience, 2023
Summary: Intradermal delivery of self-replicating RNA (srRNA) is a promising vaccine platform. We have developed an srRNA that functions optimally at around 33°C (skin temperature) and is inactivated at or above 37°C (core body temperature) as a safety ...
Tomokazu Amano   +12 more
doaj   +1 more source

Binding of RNA by the Nucleoproteins of Influenza Viruses A and B

open access: yesViruses, 2016
This paper describes a biochemical study for making complexes between the nucleoprotein of influenza viruses A and B (A/NP and B/NP) and small RNAs (polyUC RNAs from 5 to 24 nucleotides (nt)), starting from monomeric proteins.
Alice Labaronne   +5 more
doaj   +1 more source

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