Nucleoprotein content of "L" strain of Staphylococcus aureus [PDF]
Thesis (M.A.)--Boston ...
Fish, Charles Austin
core +1 more source
Genome encapsidation by orthobunyavirus nucleoproteins [PDF]
All negative-sense, single-stranded RNA (−ssRNA) viruses encode a nucleoprotein (NP), the major function of which is to bind viral RNAs and encapsidate them as ribonucleoprotein complexes (RNPs) (1, 2). Consequently, the genomes of −ssRNA viruses do not exist as naked RNA but rather as protein–RNA complexes with high-order structures. In PNAS, Li et al.
Wenjie, Zheng, Yizhi Jane, Tao
openaire +2 more sources
Inhibition of influenza virus infection by garlic oil and juice in cell culture
Abstract Background Influenza virus infections are a significant global health and economic burden. Garlic (Allium sativum) has been proposed to have antimicrobial properties. Raw garlic consumption has been widely advocated on the internet to fight influenza by many public health agencies, information of which is easily accessible by the public. There
Carla Breen +3 more
wiley +1 more source
Rift Valley fever virus detection in susceptible hosts with special emphasis in insects
Rift Valley fever phlebovirus (RVFV, Phenuiviridae) is an emerging arbovirus that can cause potentially fatal disease in many host species including ruminants and humans.
K. M. Gregor +19 more
doaj +1 more source
Innate immunity shapes the persistent transmission of plant viruses by insect vectors
In this review, we focus on two key aspects of the virus–vector interplay: (1) persistently transmitted viruses utilize host factors to overcome transmission barriers; and (2) molecular recognition activates antiviral immunity and subsequent viral counter‐defense. Understanding these interactions offers critical insights for developing novel strategies
Gang Lu, Chuanxi Zhang, Junmin Li
wiley +1 more source
The First Complete Genome Sequence of a Novel Tetrastichus brontispae RNA Virus-1 (TbRV-1)
The complete sequence of a novel RNA virus isolated from Tetrastichus brontispae (TbRV-1) was determined to be 12,239 nucleotides in length with five non-overlapping, linearly arranged coding sequences (CDS), potentially encoding nucleoproteins ...
E Meng +8 more
doaj +1 more source
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu +10 more
wiley +1 more source
Mutations in Escherichia Coli Induced by Chemical Agents [PDF]
For over two decades geneticists have been interested in the possibility of inducing mutations with chemicals. Particularly, it has been hoped that mutagenic compounds might be discovered which, through their specificity of action, would lead to some ...
Witkin, E. M.
core +1 more source
SOX30 Governs Synaptonemal Complex Assembly and Homologous Recombination in Male Meiosis
The transcription factor SOX30 directly binds promoter regions of SYCE1 and SYCE2 to mediate their transcriptional activation, thereby enabling proper assembly of central elements within the synaptonemal complex. Structural destabilisation of the synaptonemal complex in Sox30 KK spermatocytes triggers synaptic discontinuity, impairs homologous ...
Kangle Liu +16 more
wiley +1 more source
The N-terminal fragment of a PB2 subunit from the influenza A virus (A/Hong Kong/156/1997 H5N1) effectively inhibits RNP activity and viral replication. [PDF]
Influenza A virus has a RNA-dependent RNA polymerase (RdRp) that is composed of three subunits (PB1, PB2 and PA subunit), which assemble with nucleoproteins (NP) and a viral RNA (vRNA) to form a RNP complex in the host nucleus.
Takahito Kashiwagi +6 more
doaj +1 more source

