Results 81 to 90 of about 7,536 (222)
Proteostasis of organelles in aging and disease
The FEBS Journal, EarlyView.Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi +5 more
wiley +1 more source
A catalatic nucleoprotein of baker's yeast [PDF]
FEBS Letters, 1978 Some years ago we reported the existence in Saccharomyces cerevisiae of an atypical catalase, which we named catalase A; upon purification, this proved to be a heme-containing tetramer with a lower molecular weight (180 000) than usual for catalases of any species [ 1.1. Catalase A did not cross-react irnmunologicahy [l] with the typical catalase (mol.
Seah, Tony C.M. +2 more
openaire +2 more sources
Journal of Integrative Plant Biology, EarlyView.This review focuses on mitogen‐activated protein kinase (MAPK) activation and summarizes how plants regulate and integrate MAPK signaling in modulating plant immune responses. It also examines the effectors pathogens have evolved to manipulate MAPK activation and thereby inhibit plant immunity.
Guitao Zhong +3 more
wiley +1 more source
Marine Drugs, 2016 Dietary nucleotides play a role in maintaining the immune responses of both animals and humans. Oral administration of nucleic acids from salmon milt have physiological functions in the cellular metabolism, proliferation, differentiation, and apoptosis ...
Akiko Kojima-Yuasa +7 more
doaj +1 more source
, 2018 RIG-I is a major cytoplasmic sensor of viral pathogen-associated molecular pattern (PAMP) RNA and induces type I interferon (IFN) production upon viral infection.
Junjie Shao +5 more
core +1 more source
Zoonoses and Public Health, EarlyView.ABSTRACT Introduction Crimean‐Congo haemorrhagic fever virus (CCHFV) is a tick‐borne zoonotic pathogen of major public health importance in Africa. Although CCHFV exposure has been reported in several livestock species in Nigeria, data on equids remain limited despite their extensive involvement in livestock movement and trade.
David O. Ehizibolo +14 more
wiley +1 more source
Early Humoral Response Correlates with Disease Severity and Outcomes in COVID-19 Patients
Viruses, 2020 The Coronavirus Disease 2019 (COVID-19), caused by SARS-CoV-2, continues to spread globally with significantly high morbidity and mortality rates. Antigen-specific responses are of unquestionable value for clinical management of COVID-19 patients.
Anwar M. Hashem +24 more
doaj +1 more source
, 1959 1. A method of staining nucleic acids is described. The method depends upon (a) liberation of the phosphoryl groups of nucleic acids by inactivation of protein-bound amino groups; (b) binding of the phosphoryl groups by toluidine blue; and (c) coupling ...
ROBERT LOVE, ROSCOE H. LILES
core +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, Volume 16, Issue 6, Page 1213-1221, June 2026.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source