Results 31 to 40 of about 67,196 (148)
Centromere and Pericentromere Transcription: Roles and Regulation … in Sickness and in Health
Frontiers in Genetics, 2018 The chromosomal loci known as centromeres (CEN) mediate the equal distribution of the duplicated genome between both daughter cells. Specifically, centromeres recruit a protein complex named the kinetochore, that bi-orients the replicated chromosome ...
Ksenia Smurova, Peter De Wulf
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Conformational Studies of Two Non‐histone Chromosomal Proteins and Their Interactions with DNA [PDF]
European Journal of Biochemistry, 1976 The conformational properties of two non-histone chromosomal proteins (high-mobility-group proteins 1 and 2) have been studied by spectroscopic methods. The interaction of high-mobility-group protein 1 with DNA has also been studied. 1. Circular dichroism results indicate that in the presence of salt both proteins are 40-50% helical between pH 1 and 9.
P D, Cary +5 more
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Phosphorylation of non-histone proteins in the regulation of chromosome structure and function [PDF]
Journal of Cellular Physiology, 1975 Non-histone chromosomal proteins are phosphorylated and dephosphorylated within the intact nucleus by two independent sets of reactions, a protein kinase reaction which transfers the terminal phosphate group of a variety of nucleoside and deoxynucleoside triphosphates to serine and threonine residues in the proteins, and a phosphatase reaction which ...
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PLoS Genetics, 2020 Restricting the localization of the histone H3 variant CENP-A (Cse4 in yeast, CID in flies) to centromeres is essential for faithful chromosome segregation.
Wei-Chun Au +17 more
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The Similarity between the Primary Structures of Two Non‐histone Chromosomal Proteins [PDF]
European Journal of Biochemistry, 1976 A comparison has been made of two non‐histone chromosomal proteins, high‐mobility‐group proteins 1 and 2. Peptides produced from the two proteins by various chemical and enzymic cleavages have been compared by polyacrylamide gel electrophoresis and peptide mapping.
J M, Walker, G H, Goodwin, E W, Johns
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Transcriptional and genomic mayhem due to aging-induced nucleosome loss in budding yeast
Microbial Cell, 2014 All eukaryotic genomes are assembled into a nucleoprotein structure termed chromatin, which is comprised of regular arrays of nucleosomes. Each nucleosome consists of eight core histone protein molecules around which the DNA is wrapped 1.75 times.
Zheng Hu +3 more
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Comparative Cytogenetics, 2014 Karyotype analysis of nine strains of the peach-potato aphid Myzus persicae (Sulzer, 1776), collected on Lavandula sp. plants, evidenced showed that five of them had a standard 2n = 12 karyotype, one possessed a fragmentation of the X chromosome ...
Mauro Mandrioli +2 more
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Epigenetics & ChromatinTIP60 is a crucial lysine acetyltransferase protein that catalyzes the acetylation of histone and non-histone proteins. This enzyme plays a crucial role in maintaining genomic integrity, by participating in DNA damage repair, ensuring accurate ...
Himanshu Gupta, Ashish Gupta
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Rad51-Rad52 mediated maintenance of centromeric chromatin in Candida albicans.
PLoS Genetics, 2014 Specification of the centromere location in most eukaryotes is not solely dependent on the DNA sequence. However, the non-genetic determinants of centromere identity are not clearly defined.
Sreyoshi Mitra +4 more
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PLoS GeneticsThe kinetochore, a megadalton structure composed of centromeric (CEN) DNA and protein complexes, is required for faithful chromosome segregation in eukaryotes.
Prashant K Mishra +11 more
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