Results 11 to 20 of about 12,009,217 (285)
Phosphorylation of non-histone proteins in the regulation of chromosome structure and function [PDF]
Journal of Cellular Physiology, 1975 Non-histone chromosomal proteins are phosphorylated and dephosphorylated within the intact nucleus by two independent sets of reactions, a protein kinase reaction which transfers the terminal phosphate group of a variety of nucleoside and deoxynucleoside triphosphates to serine and threonine residues in the proteins, and a phosphatase reaction which ...
Kleinsmith, Lewis J.
openaire +3 more sources
Functional Diversity of Non-Histone Chromosomal Protein HmgB1 [PDF]
International Journal of Molecular Sciences, 2020 The functioning of DNA in the cell nucleus is ensured by a multitude of proteins, whose interactions with DNA as well as with other proteins lead to the formation of a complicated, organized, and quite dynamic system known as chromatin. This review is devoted to the description of properties and structure of the progenitors of the most abundant non ...
Elena Chikhirzhina +4 more
openaire +2 more sources
Hepatocyte Chromosomal Non‐histone Proteins in Developing Rats [PDF]
European Journal of Biochemistry, 1979 Rat hepatocytes taken at different stages of the perinatal period were partially purified. On sodium dodecylsulphate acrylamide electrophoresis chromosomal non‐histone proteins showed important variations in complexity during development. Chromosomal phosvitin kinase strongly increased during the last days of fetal life; it strongly decreased just ...
C, Guguen-Guillouzo +2 more
openaire +2 more sources
Studies on histones and non-histone proteins from rats treated with dimethylnitrosamine
, 1979 A study has been made of the histone and non-histone chromosomal proteins of rat liver after treatment in vivo with dimethylnitrosamine (DMN) (2 mg/kg). DMN was found not to affect histone turnover, as measured by 3H-labelled amino-acids incorporation. A
Galbraith, A., Itzhaki, Ruth F.
core +5 more sources
Non‐histone Chromosomal Proteins [PDF]
European Journal of Biochemistry, 1975 We describe a method for fractionation of chromatin components by selective dissociation with salt in buffers containing 5 M urea in combination with chromatography on hydroxyapatite at 4 °C. This results in two histone and four non‐histone fractions which are recovered in high yield and with minimal proteolytic contamination.Template capacity ...
Blüthmann, H., Mrozek, S., Gierer, A.
openaire +3 more sources
Lysine succinylation on non-histone chromosomal protein HMG-17 (HMGN2) regulates nucleosomal DNA accessibility by disrupting the HMGN2–nucleosome association [PDF]
, 2021 Lysine succinylation (Ksucc) is a novel posttranslational modification that frequently occurs on chromatin proteins including histones and non-histone proteins.
Tian, G, Li, XD, Liu, Z, JING, Y, QIN, X
core +1 more source
PLoS Genetics, 2021 Aberrant repair of DNA double-strand breaks can recombine distant chromosomal breakpoints. Chromosomal rearrangements compromise genome function and are a hallmark of ageing.
David A Ellis +9 more
doaj +1 more source
SUMO control of centromere homeostasis
Frontiers in Cell and Developmental Biology, 2023 Centromeres are unique chromosomal loci that form the anchorage point for the mitotic spindle during mitosis and meiosis. Their position and function are specified by a unique chromatin domain featuring the histone H3 variant CENP-A.
Sebastiaan J. W. van den Berg +2 more
doaj +1 more source
The DNA intercalators ethidium bromide and propidium iodide also bind to core histones
FEBS Open Bio, 2014 Eukaryotic DNA is compacted in the form of chromatin, in a complex with histones and other non-histone proteins. The intimate association of DNA and histones in chromatin raises the possibility that DNA-interactive small molecules may bind to chromatin ...
Amrita Banerjee +6 more
doaj +1 more source
PLoS ONE, 2023 Acetylation of lysine residues is an important and common post-translational regulatory mechanism occurring on thousands of non-histone proteins. Lysine deacetylases (KDACs or HDACs) are a family of enzymes responsible for removing acetylation.
Tasha B Toro +4 more
doaj +1 more source