Results 11 to 20 of about 67,067 (247)
Chromosomes as Sources of Taxonomic Information for Plant Systematics and Evolution [PDF]
Taeckholmia, 2022 Chromosomes are the units of inheritance within the nuclei of all eukaryote cells and carry the genes as DNA packaged in the chromosomes forming the chromatin fibril with histone proteins.
Abdelfattah Badr
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Non‐histone Chromosomal Proteins [PDF]
European Journal of Biochemistry, 1975 We describe a method for fractionation of chromatin components by selective dissociation with salt in buffers containing 5 M urea in combination with chromatography on hydroxyapatite at 4 °C. This results in two histone and four non‐histone fractions which are recovered in high yield and with minimal proteolytic contamination.Template capacity ...
Blüthmann, H., Mrozek, S., Gierer, A.
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PLoS Genetics, 2021 Aberrant repair of DNA double-strand breaks can recombine distant chromosomal breakpoints. Chromosomal rearrangements compromise genome function and are a hallmark of ageing.
David A Ellis +9 more
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Degradation of RNA during lysis of Escherichia coli cells in agarose plugs breaks the chromosome. [PDF]
PLoS ONE, 2017 The nucleoid of Escherichia coli comprises DNA, nucleoid associated proteins (NAPs) and RNA, whose role is unclear. We found that lysing bacterial cells embedded in agarose plugs in the presence of RNases caused massive fragmentation of the chromosomal ...
Sharik R Khan, Andrei Kuzminov
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SUMO control of centromere homeostasis
Frontiers in Cell and Developmental Biology, 2023 Centromeres are unique chromosomal loci that form the anchorage point for the mitotic spindle during mitosis and meiosis. Their position and function are specified by a unique chromatin domain featuring the histone H3 variant CENP-A.
Sebastiaan J. W. van den Berg +2 more
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The DNA intercalators ethidium bromide and propidium iodide also bind to core histones
FEBS Open Bio, 2014 Eukaryotic DNA is compacted in the form of chromatin, in a complex with histones and other non-histone proteins. The intimate association of DNA and histones in chromatin raises the possibility that DNA-interactive small molecules may bind to chromatin ...
Amrita Banerjee +6 more
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PLoS ONE, 2023 Acetylation of lysine residues is an important and common post-translational regulatory mechanism occurring on thousands of non-histone proteins. Lysine deacetylases (KDACs or HDACs) are a family of enzymes responsible for removing acetylation.
Tasha B Toro +4 more
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Interaction of Non-histone Chromosomal Proteins HMG1 and HMG2 with DNA [PDF]
European Journal of Biochemistry, 1977 Interaction between non-histone protein HMG1 or HMG2 and DNA has been studied by using thermal denaturation and circular dichroism (CD) spectroscopy. We have made the following observations. 1. The binding of each of these two proteins to DNA stabilizes the latter, as shown by an increase in melting temperature of 20 degrees C (from 45 degrees C to ...
S S, Yu +3 more
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Selfish chromosomal drive shapes recent centromeric histone evolution in monkeyflowers.
PLoS Genetics, 2021 Centromeres are essential mediators of chromosomal segregation, but both centromeric DNA sequences and associated kinetochore proteins are paradoxically diverse across species.
Findley R Finseth +2 more
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Spt2p defines a new transcription-dependent gross chromosomal rearrangement pathway.
PLoS Genetics, 2008 Large numbers of gross chromosomal rearrangements (GCRs) are frequently observed in many cancers. High mobility group 1 (HMG1) protein is a non-histone DNA-binding protein and is highly expressed in different types of tumors.
Nilabja Sikdar +4 more
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