Results 101 to 110 of about 131,087 (254)

Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia

Nature Communications, 2016
Acute lymphoblastic leukaemia is characterized by chromosomal rearrangements. Here, the authors carry out RNA-sequencing on a large cohort of patients and identify recurrent rearrangements of MEF2D, which lead to increased transcriptional activity of the
Zhaohui Gu, Michelle Churchman, Kathryn Roberts, Yongjin Li, Yu Liu, Richard C. Harvey, Kelly McCastlain, Shalini C. Reshmi, Debbie Payne-Turner, Ilaria Iacobucci, Ying Shao, I-Ming Chen, Marcus Valentine, Deqing Pei, Karen L. Mungall, Andrew J. Mungall, Yussanne Ma, Richard Moore, Marco Marra, Eileen Stonerock, Julie M. Gastier-Foster, Meenakshi Devidas, Yunfeng Dai, Brent Wood, Michael Borowitz, Eric E. Larsen, Kelly Maloney, Leonard A. Mattano Jr, Anne Angiolillo, Wanda L. Salzer, Michael J. Burke, Francesca Gianni, Orietta Spinelli, Jerald P. Radich, Mark D. Minden, Anthony V. Moorman, Bella Patel, Adele K. Fielding, Jacob M. Rowe, Selina M. Luger, Ravi Bhatia, Ibrahim Aldoss, Stephen J. Forman, Jessica Kohlschmidt, Krzysztof Mrózek, Guido Marcucci, Clara D. Bloomfield, Wendy Stock, Steven Kornblau, Hagop M. Kantarjian, Marina Konopleva, Elisabeth Paietta, Cheryl L. Willman, Mignon L. Loh, Stephen P. Hunger, Charles G. Mullighan   +55 more
doaj   +1 more source

Chromosomal Rearrangements Not Detected in Rhododendrons with Tissue Proliferation Disorder [PDF]

, 1997
Lisa J. Rowland, Amnon Levi, Richard H. Zimmerman   +2 more
openalex   +1 more source

Cytogenomic characterization of karyotypes with additional autosomal material

Scientific Reports
Chromosomal rearrangements involving additional material in individuals with phenotypic alterations usually result in partial trisomy, often accompanied by partial monosomy.
Priscila Soares Rodrigues, Bruna Burssed, Fernanda Bellucco, Débora Cristina Batista Rosolen, Chong Ae Kim, Maria Isabel Melaragno   +5 more
doaj   +1 more source

Functional and Comparative Analysis of Centromeres Reveals Clade-Specific Genome Rearrangements in Candida auris and a Chromosome Number Change in Related Species

, 2021
Aswathy Narayanan, Rakesh Netha Vadnala, Promit Ganguly, Pavitra Selvakumar, Shivaprakash M. Rudramurthy, Rajendra Prasad, Arunaloke Chakrabarti, Rahul Siddharthan, Kaustuv Sanyal   +8 more
openalex   +1 more source

DNA-PKcs suppresses illegitimate chromosome rearrangements

Nucleic Acids Research
Abstract Two DNA repair pathways, non-homologous end joining (NHEJ) and alternative end joining (A-EJ), are involved in V(D)J recombination and chromosome translocation. Previous studies reported distinct repair mechanisms for chromosome translocation, with NHEJ involved in humans and A-EJ in mice predominantly.
Jinglong Wang, Cheyenne A Sadeghi, Richard L Frock   +2 more
openaire   +2 more sources

A Computational Method for the Rate Estimation of Evolutionary Transpositions

, 2015
Genome rearrangements are evolutionary events that shuffle genomic architectures. Most frequent genome rearrangements are reversals, translocations, fusions, and fissions.
J. Ma, J. Ranz, J.H. Nadeau, L. Bulteau, M. Alekseyev, M. Bader, M.A. Alekseyev, P.A. Pevzner, S. Yancopoulos   +8 more
core   +1 more source

PGD for a complex chromosomal rearrangement by array comparative genomic hybridization [PDF]

, 2011
Evelyne Vanneste, Cindy Melotte, Thierry Voet, Caroline Robberecht, Sophie Debrock, A. Pexsters, C. Staessen, Carla Tomassetti, Eric Legius, Thomas D’Hooghe, Joris Vermeesch   +10 more
openalex   +1 more source

Chromosomal rearrangements and transposable elements in locally adapted island Drosophila [PDF]

, 2021
Brandon A. Turner, Theresa R. Miorin, Nicholas B. Stewart, Robert W. Reid, Cathy C. Moore, Rebekah L. Rogers   +5 more
openalex   +1 more source

The Rad1-Rad10 Complex Promotes the Production of Gross Chromosomal Rearrangements From Spontaneous DNA Damage in Saccharomyces cerevisiae [PDF]

, 2005
Ji‐Young Hwang, Stephanie Smith, Kyungjae Myung   +2 more
openalex   +1 more source

The canonical non-homologous end joining factor XLF promotes chromosomal deletion rearrangements in human cells [PDF]

, 2019
Ragini Bhargava, Felicia Wednesday Lopezcolorado, Linda Jillianne Tsai, Jeremy M. Stark   +3 more
openalex   +1 more source