Results 81 to 90 of about 267,700 (194)

Comparative Chromosome Painting Clarifies the Intraspecific Chromosomal Variation in Two Ctenomys Species (Rodentia: Ctenomyidae)

Animals
Background: Ctenomys is a subterranean rodent genus known for exhibiting the highest levels of chromosome variation, both among species (2n = 10 to 70) and within species.
Thays Duarte de Oliveira, Natasha Ávila Bertocchi, Luciano Cesar Pozzobon, Ivanete de Oliveira Furo, Edivaldo Herculano Corrêa de Oliveira, Jorge C. Pereira, Malcolm A. Ferguson-Smith, Rafael Kretschmer, Thales R. O. de Freitas   +8 more
doaj   +1 more source

LINE-1 insertion intermediates recombine with one another or with DNA breaks to form genome rearrangements

Nature Communications
LINE-1 (L1) retrotransposition is common in human cancers and rearrangements at insertion sites can contribute to cancer-driving oncogene amplifications and promote genome instability.
Carlos Mendez-Dorantes, Jupiter C. Kalinowski, Aidan Burn, Phillip Schofield, Cheuk-Ting Law, Esin Isik, Kathleen H. Burns   +6 more
doaj   +1 more source

Functional consequences of chromosomal rearrangements on gene expression: not so deleterious after all?

, 2019
International audienceResearch Highlights: TADs are evolutionarily conserved regions largely overlapping with regulatory domains Deleting TAD boundaries only mildly affects gene expression Chromosomal inversions affecting TAD boundaries are usually ...
Ghavi-Helm, Yad
core   +1 more source

Analysis of chromosomal rearrangements after replication restart

, 2014
Impediments to DNA replication are known to induce gross chromosomal rearrangements (GCRs) and copy-number variations (CNVs). GCRs and CNVs underlie human genomic disorders and are a feature of cancer. During cancer development, environmental factors and
Saed Mohebi (500085)
core  

It takes two transposons to tango: transposable-element-mediated chromosomal rearrangements.

, 2015
Transposable elements (TEs) promote various chromosomal rearrangements more efficiently, and often more specifically, than other cellular processes1-3. One explanation of such events is homologous recombination between multiple copies of a TE present in ...
Gray, Y H M
core   +1 more source

Cytogenomic characterization of karyotypes with additional autosomal material

Scientific Reports
Chromosomal rearrangements involving additional material in individuals with phenotypic alterations usually result in partial trisomy, often accompanied by partial monosomy.
Priscila Soares Rodrigues, Bruna Burssed, Fernanda Bellucco, Débora Cristina Batista Rosolen, Chong Ae Kim, Maria Isabel Melaragno   +5 more
doaj   +1 more source

Chromosomal Study of Couples with the History of Recurrent Spontaneous Abortions with Diagnosed Blightded Ovum [PDF]

International Journal of Molecular and Cellular Medicine, 2013
Spontaneous abortion (SAb) is the most common complication of early pregnancy. Numerous risk factors are associated with an increased risk of pregnancy loss such as: Blighted ovum.
Sahar Shekoohi, Majid Mojarrad, Reza Raoofian, shahab ahmadzadeh, Salmah Mirzaie, Mohammad Hassanzadeh-Nazarabadi   +5 more
doaj  

The Two Faces of Saccharomyces cerevisiae RAD9 Function in Homologous Recombination: Suppressor and Promoter of Genome Instability

DNA
Recombinogenic DNA damage can initiate chromosomal rearrangements that can alter gene expression or accelerate cancer progression in higher eukaryotes.
Michael Fasullo
doaj   +1 more source

Chromosomal rearrangements in rock wallabies, Petrogale (Marsupialia: Macropodidae). II. G-banding analysis of Petrogale godmani

, 1989
Chromosomal rearrangements in the two currently recognised races of Petrogale godmani were examined using C- and G-banding. The nominate race P. godmani godmani (2n = 20) was found to possess an inverted chromosome 5 and an acrocentric 6–10 fusion ...
P. G. Johnston, M. D. B. Eldridge, R. L. Close, P. S. Lowry   +3 more
core   +1 more source

Frequency of rearranged constituents for all chromosomal rearrangements in the Simulium cholodkovskii lineage, relative to the Simulium subgeneric standard.

, 2016
Frequency of rearranged constituents for all chromosomal rearrangements in the Simulium cholodkovskii lineage, relative to the Simulium subgeneric standard.
Peter H. Adler (443785), Oyunchuluun Yadamsuren (3162795), William S. Procunier (3162792)   +2 more
core   +1 more source