Results 71 to 80 of about 1,114,920 (242)

Comparative chromosome band mapping in primates byin situ suppression hybridization of band specific DNA microlibraries [PDF]

, 1991
A DNA-library established from microdissected bands 8q23 to 8q24.1 of normal human chromosomes 8 (Lüdecke et al., 1989) was used as a probe for chromosomal in situ suppression (CISS-) hybridization to metaphase chromosomes of man and primates including ...
A. Jauch, B. Dutrillaux, B. Horsthemke, C. Lengauer, C. Lengauer, D. Pinkel, D. Pinkel, H. J. Lüdecke, H.J. Lüdecke, J. Wienberg, J. Wienberg, J.J. Yunis, M. Klever, M. Small, P. Lichter, P.A. Lalley, R. Stanyon, R. Stanyon, R. Stanyon, S.J. O'Brien, T. Cremer   +20 more
core   +1 more source

PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA

Nature Communications, 2017
Chromosomal rearrangements are essential events in the pathogenesis of both malignant and nonmalignant disorders, yet the factors affecting their formation are incompletely understood.
Tovah A. Day, Jacob V. Layer, J. Cleary, Srijoy Guha, K. Stevenson, Trevor Tivey, Sunhee Kim, Anna C. Schinzel, F. Izzo, John G Doench, D. Root, W. Hahn, B. Price, D. Weinstock   +13 more
semanticscholar   +1 more source

High-resolution detection of chromosomal rearrangements in leukemias through mate pair whole genome sequencing.

PLoS ONE, 2018
The detection of recurrent somatic chromosomal rearrangements is standard of care for most leukemia types. Even though karyotype analysis-a low-resolution genome-wide chromosome analysis-is still the gold standard, it often needs to be complemented with ...
Anh Nhi Tran, Fulya Taylan, Vasilios Zachariadis, Ingegerd Ivanov Öfverholm, Anna Lindstrand, Francesco Vezzi, Britta Lötstedt, Magnus Nordenskjöld, Ann Nordgren, Daniel Nilsson, Gisela Barbany   +10 more
doaj   +1 more source

Molecular methods for genomic analyses of variant PML-RARA or other RARA-related chromosomal translocations in acute promyelocytic leukemia [PDF]

, 2012
TO THE EDITOR: We read an interesting paper by Palta et al. in a recent issue of the Korean Journal of Hematology titled, "ZBTB16-RARA variant of acute promyelocytic leukemia with tuberculosis: a case report and review of literature" [1].
Kim, Min Jin, Marschalek, Rolf, Meyer, Claus, Park, Tae Sung, Yang, John Jeongseok   +4 more
core   +1 more source

Transcription as a Threat to Genome Integrity [PDF]

, 2016
Genomes undergo different types of sporadic alterations, including DNA damage, point mutations, and genome rearrangements, that constitute the basis for evolution.
Aguilera López, Andrés, Gaillard, Hélène   +1 more
core   +1 more source

Chromosomal rearrangements in chondromatous tumors [PDF]

Cancer, 1990
Short-term cultures from 16 chondromatous tumors, 15 primary and one recurrent, were analyzed cytogenetically. Clonal chromosome aberrations were found in one of six benign tumors and in seven of ten malignant tumors. A chondroma had a complex translocation involving chromosomes X, 8, 12, and 13, as well as a deletion of the derivative chromosome 8. In
N, Mandahl, S, Heim, K, Arheden, A, Rydholm, H, Willén, F, Mitelman   +5 more
openaire   +2 more sources

A Preliminary Investigation on the Chromosome Aberrations in Acute Lymphoblastic Leukaemia Using Multiprobe Fluorescence In Situ Hybridization Panel

Bezmiâlem Science, 2022
Objective:Acute lymphoblastic leukemia (ALL) is a disease related to the overproduction of immature lymphocytes. For diagnosis and classification of ALL, recognizing chromosome aberrations using conventional cytogenetic analysis (CCA) is essential ...
Bengisu GÖKKAYA, Sezen ATASOY, Ayşe ÇIRAKOĞLU, Yelda TARKAN ARGÜDEN, R. Dilhan KURU, Şükriye YILMAZ, Şeniz ÖNGÖREN, Ayhan DEVİREN   +7 more
doaj   +1 more source

Three chromosomal rearrangements promote genomic divergence between migratory and stationary ecotypes of Atlantic cod

Scientific Reports, 2016
Identification of genome-wide patterns of divergence provides insight on how genomes are influenced by selection and can reveal the potential for local adaptation in spatially structured populations. In Atlantic cod – historically a major marine resource
P. Berg, Bastiaan Star, C. Pampoulie, M. Sodeland, J. M. Barth, H. Knutsen, K. Jakobsen, S. Jentoft   +7 more
semanticscholar   +1 more source

A strategy for the characterization of minute chromosome rearrangements using multiple color fluorescence in situ hybridization with chromosome-specific DNA libraries and YAC clones [PDF]

, 1993
The identification of marker chromosomes in clinical and tumor cytogenetics by chromosome banding analysis can create problems. In this study, we present a strategy to define minute chromosomal rearrangements by multicolor fluorescence in situ ...
A Kallioniemi, Anna Jauch, B Dutrillaux, C Lengauer, C Lengauer, CC Collins, Christoph Lengauer, D Pinkel, Detlev Schindler, DH Ledbetter, DH Ledbetter, GD Johnson, H Telenius, Harold C. Riethman, Helen Donis-Keller, J Grouchy de, J Sambrook, J Wiegant, JG Dauwerse, JS Heslop-Harrison, JW IJdo, Michael R. Speicher, P Lichter, P Lichter, PM Nederlof, PM Nederlof, S Manoir du, Susanne Popp, T Ried, T Ried, T Ried, Thomas Cremer   +31 more
core   +1 more source

High-Definition Cytogenetic Mapping of modern sugarcane cultivars by Oligo-FISH

Industrial Crops and Products
Sugarcane (Saccharum spp.), a dual-purpose crop valued for sugar and energy production, serves as an important industrial raw material and has substantial economic impact.
Qilong Ling, Junpeng Yang, Yu Tang, Xiaoying Huang, Wei Yao, Zuhu Deng, Muqing Zhang, Fan Yu   +7 more
doaj   +1 more source