Results 91 to 100 of about 982,148 (390)

Chromosomal rearrangements in cattle and pigs revealed by chromosome microdissection and chromosome painting

Genetics Selection Evolution, 2003
A pericentric inversion of chromosome 4 in a boar, as well as a case of (2q-;5p+) translocation mosaicism in a bull were analysed by chromosome painting using probes generated by conventional microdissection.
Yerle Martine, Ducos Alain, Pinton Alain
doaj   +1 more source

Study of two markers of apoptosis and meiotic segregation in ejaculated sperm of chromosomal translocation carrier patients.

Human Reproduction, 2006
BACKGROUND To try to explain the infertility of chromosomal translocation carrier patients, we compared the expression of two markers of apoptosis in the sperm of patients and of fertile donors, and we studied the meiotic segregation in the ejaculated ...
F. Brugnon, E. V. Assche, G. Verheyen, B. Sion, Daniel Boucher, J. Pouly, L. Janny, P. Devroey, I. Liebaers, A. Steirteghem   +9 more
semanticscholar   +1 more source

Chromosomal in situ suppression hybridization of immunologically classified mitotic cells in hematologic malignancies [PDF]

, 1992
Chromosomal in situ suppression (CISS) hybridization was performed with library DNA from sorted human chromosomes 8, 9, 15, 17, 21, and 22 on immunologically stained bone marrow cells of four patients with a hematologic neoplasm, including two patients ...
Arnoldus, Cremer, Cremer, Dauwerse, Edwards, Erber, Hopman, Johnson, Jotterand Bellomo, Knuutila, Knuutila, Larramendy, Larramendy, Lichter, Lichter, Marianne Tiainen, Martine Jotterand Bellomo, Patricia Emmerich, Perez Losada, Pinkel, Pinkel, Popp, Sakari Knuutila, Susanne Popp, Tapani Ruutu, Teerenhovi, Thomas Cremer, Valerie Parlier, Wessman, Willard   +29 more
core   +1 more source

The Rise of Mechanobiology for Advanced Cell Engineering and Manufacturing

Advanced Materials, EarlyView.
With the growing demand for cell‐based therapies, efficient cellular engineering is crucial. This review calls for greater recognition of mechanobiology principles applied through advanced biomaterial designs, mechanical confinement, and highlights recent advances using micro/nanotechnologies to enhance cell manufacturing.
Huan Ting Ong, M Sriram, Hepi Hari Susapto, Yixuan Li, Yuan Jiang, Nicolas H. Voelcker, Jennifer L. Young, Andrew W. Holle, Roey Elnathan   +8 more
wiley   +1 more source

Prenatal diagnosis and genetic counseling of mosaicism for chromosome t (7; 14) with a favorable outcome

Clinical and Experimental Obstetrics & Gynecology, 2020
We report a case of prenatal diagnosis of mosaicism for chromosome t (7; 14) with a favorable fetal outcome. Similar chromosomal abnormalities have been observed in patients with hematologic malignancy.
D. Lu, D. Cao, Q. Zhao, X. Chen
doaj   +1 more source

Chromosomal Translocation and Segmental Duplication in Cryptococcus neoformans

Eukaryotic Cell, 2005
Large chromosomal events such as translocations and segmental duplications enable rapid adaptation to new environments. Here we marshal genomic, genetic, meiotic mapping, and physical evidence to demonstrate that a chromosomal translocation and segmental
J. A. Fraser, Johnny C. Huang, Read Pukkila-Worley, J. Alspaugh, T. G. Mitchell, J. Heitman   +5 more
semanticscholar   +1 more source

Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1 [PDF]

, 2014
DNA double-strand breaks (DSBs) are repaired by nonhomologous end joining (NHEJ) or homologous recombination (HR). The C terminal binding protein–interacting protein (CtIP) is phosphorylated in G2 by cyclin-dependent kinases to initiate resection and ...
Anantha, Anger, Bahassi, Beausoleil, Bernard S. Lopez, Beucher, Boboila, Bunting, Chapman, Chapman, Chen, Darroudi, Davis, de Cárcer, Deckbar, Di Virgilio, Donnianni, Elia, Escribano-Díaz, Feng, Golsteyn, Gotoh, Helmink, Huertas, Huertas, Jackman, Jackson, Jiadong Wang, Julia Künzel, Junjie Chen, Kim, Kühne, Lansing, Lee, Lee-Theilen, Li, Lin Feng, Lukas, Lukas, Löbrich, Mansour, Markus Löbrich, Mladenov, Monika Steinlage, Mosesso, Moynahan, Naim, Nakamura, Nodar Makharashvili, Nussenzweig, Nussenzweig, Olivia Barton, Panier, Pearce, Penny A. Jeggo, Peterson, Polo, Quennet, Rass, Reczek, Reinhardt, Rief, Ronja Diemer-Biehs, Rothkamm, Sandro Conrad, Sartori, Shibata, Steffen C. Naumann, Stephan, Tanya T. Paull, van Gent, van Gent, Wang, Wang, Wang, Weichert, Weichert, Weinstock, Ying, Yu, Yu, Yun, Zhang, Zimmerman, Zimmermann   +84 more
core   +1 more source

PARP1 is required for chromosomal translocations

Blood, 2013
Key Points Chromosomal translocations are mediated by PARP1 and can be suppressed by the clinical PARP1 inhibitors.
Christopher R. Cogle, Jac A. Nickoloff, Yuehan Wu, David M. Weinstock, Lijian Shao, Virginia M. Klimek, Elizabeth A. Williamson, Robert Hromas, Martin Hauer-Jensen, Rupak Pathak, Yu Zhang, Suk Hee Lee, Daohong Zhou, Justin Wray, Sudha B. Singh   +14 more
openaire   +4 more sources

Exploring AAV‐Mediated Gene Therapy for Inner Ear Diseases: from Preclinical Success to Clinical Potential

Advanced Science, EarlyView.
Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu, Wuhui He, Yun Xiao, Qiong Wu, Qing Zhang, Tiesong Zhang, Lei Xu, Xinyi Pang   +7 more
wiley   +1 more source

Association pattern of reciprocal translocations induced by chemicals and ionizing radiation in mouse germ cells: a comparison between single and combined treatments [PDF]

, 2011
The similarity degree of chemical, ionizing radiation, and combined treatments of chemical plus ionizing radiation in their capacity to induce reciprocal translocations was analyzed by means of multivariate analysis techniques on mice germ cells.
de Luca, Julio Cesar, Ortiz Jaureguizar, Edgardo, Posadas, Paula Elena   +2 more
core   +1 more source