Evaluation of potential role of R-loop and G-quadruplex DNA in the fragility of c-MYC during chromosomal translocation associated with Burkitt's lymphoma. [PDF]
Kumari N+12 more
europepmc +1 more source
A Family Apparently Showing Transmission of a Translocation Between Chromosome 3 and One of the `X-6-12' or `C' Group [PDF]
G. R. CLARKE+3 more
openalex +1 more source
As an m6A reader, hnRNPA2B1 predominantly regulates specific transcripts (e.g., Ep400, Rrs1) that are essential for chromosome organization and remodeling in an m6A‐dependent manner. Furthermore, it is demonstrated to interact with factors involved in mRNA processing and translation. This dual functionality is pivotal for ensuring the proper occurrence
Lisha Yin+11 more
wiley +1 more source
THE EFFECTS OF HETEROZYGOUS AUTOSOMAL TRANSLOCATIONS ON RECOMBINATION IN THE X CHROMOSOME OF DROSOPHILA MELANOGASTER [PDF]
Claude W Hinton
openalex +1 more source
Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles [PDF]
Notch is a highly conserved transmembrane protein that is involved in cell fate decisions and is found in organisms ranging from Drosophila to humans. A human homologue of Notch, TAN1, was initially identified at the chromosomal breakpoint of a subset of
Aster, Jon C.+6 more
core
Here, it is revealed that CAF‐secreted exosomal CCT6A enhances stemness, chemoresistance, and glycolysis in GC via the β‐catenin/c‐Myc/DDIT4‐TXNIP axis. Furthermore, CCT6P1, a pseudogene of CCT6A, is identified as upregulating CCT6A by competitively binding miR‐922, while c‐Myc transcriptionally activates both CCT6P1 and CCT6A.
Hui Sun+15 more
wiley +1 more source
Analysis of 2 men with t(8;22)(q13;q13) and t(8;14)(q13;q22) chromosomal translocation karyotypes. [PDF]
Sun Q+5 more
europepmc +1 more source
Congenital anomalies due to transmission of a chromosome translocation. [PDF]
J.E. Gray+3 more
openalex +1 more source
Ruminant meat is widely appreciated for its distinctive flavor. Lipids play a central role in influencing meat flavor, yet their genetic and biochemical basis remains largely unexplored. Here, a comprehensive lipid genetic map of sheep muscle is constructed and 20 candidate genes potentially modulating lipid levels are identified to provide a roadmap ...
Xueying Zhang+17 more
wiley +1 more source
KMT2A-rearranged acute lymphoblastic leukemia in infants: current progress and challenges
Chromosomal translocation of the KMT2A gene represents the cytogenetic hallmark of acute lymphoblastic leukemia diagnosed in infants (
Janine Stutterheim+4 more
doaj +1 more source