Results 151 to 160 of about 982,148 (390)

Chromosome translocations inGlossina austeni

Genetical Research, 1972
SUMMARYAn autosomal translocation in the tsetse flyGlossina austeniwas studied genetically, cytogenetically and for its effects on viability. Flies homo-zygous for the structural change could be identified by outcrossing to wild-type and demonstrating semi-sterility in all the progeny.A cytogenetical analysis of male meioses in samples of pupae which ...
T.A. Craig-Cameron, P.E. Pell, D. I. Southern, C. F. Curtis   +3 more
openaire   +3 more sources

YTHDC1 Is Essential for Postnatal Liver Development and Homeostasis

Advanced Science, EarlyView.
This study identifies YTHDC1 as a key regulator of postnatal liver development and disease. Hepatocyte‐specific deletion of Ythdc1 impairs hepatocyte maturation, causing liver injury, contributing to nonalcoholic steatohepatitis and hepatocellular carcinoma.
Xinzhi Li, Xueying Li, Chunhong Liu, Zhenzhi Li, Kaixin Ding, Yuxin Wang, Ning Gu, Liwei Xie, Zheng Chen   +8 more
wiley   +1 more source

Structural Basis for a Scaffolding Role of the COM Domain in Nonribosomal Peptide Synthetases

Angewandte Chemie, EarlyView.
COM domains are known as docking domains between subunits of nonribosomal peptide synthetases (NRPSs). Here, the first structure of a fused, internal COM domain with its neighboring domains is reported. Structural, biochemical and crosslinking data show that COM domains play an unexpected role in properly positioning epimerization (E) and condensation (
Julia Diecker, Benedikt Hermanns, Jennifer Rüschenbaum, René Rasche, Wolfgang Dörner, Alexander Schröder, Daniel Kümmel, Henning D. Mootz   +7 more
wiley   +2 more sources

11q13.3q13.4 deletion plus 9q21.13q21.33 duplication in an affected girl arising from a familial four-way balanced chromosomal translocation. [PDF]

Mol Genet Genomic Med, 2023
Zhang Q, Wang Y, Zhou J, Zhou R, Liu A, Meng L, Ji X, Hu P, Xu Z.   +8 more
europepmc   +1 more source

Translocations of D chromosomes in two families: t(13q14q) and t(13q14q)+(13p14p). [PDF]

, 1969
Catherine G. Palmer, P. M. Conneally, J. C. Christian   +2 more
openalex   +1 more source

Balanced Chromosomal Translocation

Definitions, 2020

semanticscholar   +1 more source

The t(8;21) chromosomal translocation in acute myelogenous leukemia modifies intranuclear targeting of the AML1/CBFα2 transcription factor

, 1999
Targeting of gene regulatory factors to specific intranuclear sites may be critical for the accurate control of gene expression. The acute myelogenous leukemia 8;21 (AML1/ETO) fusion protein is encoded by a rearranged gene created by the ETO chromosomal ...
S. McNeil, Congmei Zeng, K. Harrington, S. Hiebert, J. Lian, J. Stein, A. J. Wijnen, G. Stein   +7 more
semanticscholar   +1 more source

Chromosome translocation inPlasmodium berghei

Nucleic Acids Research, 1992
We describe a chromosome translocation in a karyotype mutant of the rodent malarial parasite Plasmodium berghei. In this mutant (named EP) a small chromosome (chromosome 7), which has exhibited a size range between 0.9 and 1.4 Mb in other clones of P. berghei, is translocated to chromosome 13 or 14 with a size of about 3 Mb.
Chris J. Janse, Jai Ramesar, Barend Mons
openaire   +3 more sources

Genomic Insights into the Origin, High Fecundity and Environmental Adaptation of Hu Sheep

Advanced Science, EarlyView.
The Hu sheep diverged from the Small‐tailed Han sheep ≈1330 years ago, and subsequently migrated from northern to warm and humid southern regions. The genes BMPR1B, UNC5C, and GRID2 play a synergistic role in the superior reproductive traits of Hu sheep.
Zexuan Liu, Na Zhang, Zilong Wen, Haitao Wang, Tingting Li, Runlin Ma, Menghua Li, Daxiang Wang, Haiping Shu, Xun Huang, Jianlin Han, Yiqiang Zhao, Qiuyue Liu   +12 more
wiley   +1 more source

KMT2A-rearranged acute lymphoblastic leukemia in infants: current progress and challenges

Haematologica
Chromosomal translocation of the KMT2A gene represents the cytogenetic hallmark of acute lymphoblastic leukemia diagnosed in infants (
Janine Stutterheim, Inge M. van der Sluis, Kirsten S. Vrenken, Rob Pieters, Ronald W. Stam   +4 more
doaj   +1 more source