Results 11 to 20 of about 85,626 (243)

A rare case of acute myeloid leukemia with t(12;19)(q13;q13)

Leukemia Research Reports, 2020
Acute myeloid leukemia (AML) is characterized by chromosomal abnormalities affecting both prognosis and course of treatment. While most AML patients have well described chromosomal aberrations, around 10% present with rare chromosomal abnormalities.We ...
Alain Chebly, Fady Gh Haddad, Josiane Bassil, Tony Yammine, Rima Korban, Warde Semaan, Fady El Karak, Hampig Raphael Kourie, Chantal Farra   +8 more
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Complex rearrangement in acute myeloid leukemia M2 with RUNX1/RUNX1T1 fusion involving chromosomes 8, 17 and 21

Molecular Cytogenetics, 2021
Background The translocation t(8;21)(q22;q22) is one of the most frequent chromosomal abnormalities associated with acute myeloid leukemia (AML) sub type M2.
Shiba Ranjan Mishra, Leena Rawal, Moneeb A. K. Othman, Atul Thatai, Aditi Sarkar, Vandana Lal, Saurabh Kumar Bhattacharya   +6 more
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Criteria to evaluate patterns of segmental and complete aneuploidies in preimplantation genetic testing for aneuploidy results suggestive of an inherited balanced translocation or inversion

F&S Reports, 2021
Objective: To define criteria for determining when preimplantation genetic testing for aneuploidy (PGT-A) results are suggestive of a potential balanced chromosomal rearrangement in the egg or sperm source and warrant karyotyping.
Alyssa C. Snider, Ph.D., C.G.C., Tristan Darvin, M.S., Lauren Spor, B.S., Adedoyin Akinwole, M.P.H., Cengiz Cinnioglu, Ph.D., Refik Kayali, Ph.D.   +5 more
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Fragility in the 14q21q translocation region

Genetics and Molecular Biology, 2002
Aphidicolin (APC)-induced chromosomal breakage was analyzed for women representing three generations of a single family and carrying a Robertsonian translocation rob(14q21q).
Stacy R. Denison, Asha S. Multani, Sen Pathak, Ira F. Greenbaum   +3 more
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Molecular characterization of TCF3::PBX1 chromosomal breakpoints in acute lymphoblastic leukemia and their use for measurable residual disease assessment

Scientific Reports, 2023
The translocation t(1;19)(q23;p13) with the resulting chimeric TCF3::PBX1 gene is the third most prevalent recurrent chromosomal translocation in acute lymphoblastic leukemia and accounts for 3–5% of cases.
Thomas Burmeister, Daniela Gröger, Nicola Gökbuget, Bernd Spriewald, Michael Starck, Ahmet Elmaagacli, Dieter Hoelzer, Ulrich Keller, Stefan Schwartz   +8 more
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Occupational exposure to pesticides and occurrence of the chromosomal translocation t(14;18) among farmers in Jordan

Toxicology Reports, 2016
Background: An increased incidence of non-Hodgkin’s lymphoma (NHL) has been reported in farmers and other occupational groups working with pesticides. In these individuals, an increased prevalence of the chromosomal translocation t(14;18)(q32;q21), one ...
Bara’a M. Qaqish, Osama Al-Dalahmah, Yousef Al-Motassem, Abdelkader Battah, Said S. Ismail   +4 more
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High Frequency of Fusion Gene Transcript Resulting From t(10;11)(p12;q23) Translocation in Pediatric Acute Myeloid Leukemia in Poland

Frontiers in Pediatrics, 2020
11q23/MLL rearrangements are frequently detected in pediatric acute myeloid leukemia. The analysis of their clinical significance is difficult because of the multitude of translocation fusion partners and their low frequency. The presence of t(10;11)(p12;
Teofila Ksiazek, Teofila Ksiazek, Malgorzata Czogala, Malgorzata Czogala, Przemyslaw Kaczowka, Przemyslaw Kaczowka, Beata Sadowska, Katarzyna Pawinska-Wasikowska, Katarzyna Pawinska-Wasikowska, Mirosław Bik-Multanowski, Barbara Sikorska-Fic, Michał Matysiak, Jolanta Skalska-Sadowska, Jacek Wachowiak, Anna Rodziewicz-Konarska, Alicja Chybicka, Katarzyna Muszynska-Rosłan, Maryna Krawczuk-Rybak, Dominik Grabowski, Jerzy Kowalczyk, Lucyna Maciejka-Kemblowska, Elzbieta Adamkiewicz-Drozynska, Wojciech Mlynarski, Renata Tomaszewska, Tomasz Szczepanski, Joanna Pohorecka, Grazyna Karolczyk, Agnieszka Mizia-Malarz, Katarzyna Mycko, Wanda Badowska, Karolina Zielezinska, Tomasz Urasinski, Irena Karpinska-Derda, Mariola Woszczyk, Małgorzata Ciebiera, Monika Lejman, Szymon Skoczen, Szymon Skoczen, Walentyna Balwierz, Walentyna Balwierz   +39 more
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Analysis of meiotic segregation modes in biopsied blastocysts from preimplantation genetic testing cycles of reciprocal translocations

Molecular Cytogenetics, 2019
Purpose To analyse the meiotic segregation modes of chromosomal structural rearrangements (PGT-SR) of reciprocal translocation in biopsied blastocysts from preimplantation genetic testing and to investigate whether any features of reciprocal ...
Jie Wang, Dong Li, Zhipeng Xu, Zhenyu Diao, Jianjun Zhou, Fei Lin, Ningyuan Zhang   +6 more
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Dynamics of Tumor Heterogeneity Derived from Clonal Karyotypic Evolution

Cell Reports, 2015
Numerical chromosomal instability is a ubiquitous feature of human neoplasms. Due to experimental limitations, fundamental characteristics of karyotypic changes in cancer are poorly understood.
Ashley M. Laughney, Sergi Elizalde, Giulio Genovese, Samuel F. Bakhoum   +3 more
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Novel t(7;10)(p22;p24) along with NPM1 mutation in patient with relapsed acute myeloid leukemia

Annals of Saudi Medicine, 2013
Chromosomal abnormalities/genetic mutations associated with hematological malignancies alter the structure and function of genes controlling cell proliferation and differentiation through multiple and complex pathways, resulting different clinical ...
Santhi Sarojam, Sureshkumar Raveendran, Geetha Narayanan, Hariharan Sreedharan   +3 more
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