Results 221 to 230 of about 85,626 (243)

MLL leukemia induction by t(9;11) chromosomal translocation in human hematopoietic stem cells using genome editing. [PDF]

Blood Adv, 2018
Schneidawind C, Jeong J, Schneidawind D, Kim IS, Duque-Afonso J, Wong SHK, Iwasaki M, Breese EH, Zehnder JL, Porteus M, Cleary ML.   +10 more
europepmc   +1 more source

Neoclassical development of genetic sexing strains for insect pest and disease vector control

Insect Science, EarlyView.
The sterile insect technique has been effectively used for decades, and an important component is the availability of sex separation systems, in particular genetic sexing strains. Classical approaches, such as irradiation‐induced chromosomal translocations, have yielded stable strains for species like the Mediterranean fruit fly.
Giovanni Petrucci, Maria‐Eleni Gregoriou, Philippos Aris Papathanos, Marc F. Schetelig, Zhijian Tu, Kostas Bourtzis   +5 more
wiley   +1 more source

Detection of sex chromosomes in Tephritid pests using R‐CQ and KAMY, two computational methods to support generic pest management applications

Insect Science, EarlyView.
Here, we present R‐CQ and KAMY, two computational methods developed for the detection of sex chromosome‐linked sequences. We evaluate their performance on newly generated chromosome‐level assemblies of four important Tephritid pest species: Ceratitis capitata, Bactrocera dorsalis, Bactrocera zonata, and Anastrepha ludens.
Dimitris Rallis, Konstantina T. Tsoumani, Flavia Krsticevic, Philippos Aris Papathanos, Georgia Gouvi, Angela Meccariello, Kostas D. Mathiopoulos, Alexie Papanicolaou   +7 more
wiley   +1 more source

IAEA Coordinated Research Project on “A generic approach for the development of genetic sexing strains for Sterile Insect Technique applications”— an overview

Insect Science, EarlyView.
Abstract The sterile insect technique (SIT) plays an important role in environmentally sustainable pest management. Its effectiveness hinges on specialized genetic tools called genetic sexing strains (GSSs), which enable the production and release of sterile male insects while excluding females.
Marc F. Schetelig, Antonios Augustinos, Kostas Bourtzis   +2 more
wiley   +1 more source

USE OF 1R CHROMOSOME TRANSLOCATIONS TO IMPROVE BREAD‐MAKING QUALITY IN TRITICALE

, 2009
Petr Martinek, Tomáš Vyhnánek, J. Kučerová, M. Hromádko   +3 more
openalex   +1 more source

Hox Gene Variation Drives Morphological Specialization of Humpback Grouper Cromileptes altivelis

Integrative Zoology, EarlyView.
Cromileptes altivelis exhibits a distinctive “sunken head and humpback” morphology, formed through cranial remodeling. Genetic analyses identified unique amino acid variants in Hoxa7a and Hoxa10b, with functional tests confirming their role in enhancing osteoblast activity and driving cranial remodeling.
Xiaoying Cao, Zhaowei Zhong, Lisheng Wu, Quanyin Liu, Shaoxiong Ding   +4 more
wiley   +1 more source

Genome Expansion of ZPB1(a) and ZPC1(a) in Basal Species or Liver Expression of ZPB1a and ZPC1aa in Advanced Species, Two Different Strategies to Ensure Sufficient ZP Synthesis in Teleosts

Integrative Zoology, EarlyView.
We found that teleosts employed two different strategies to ensure sufficient ZP (zona pellucida) synthesis: expansion of ZPB1(a) and ZPC1(a) in basal species or liver expression of ZPB1a and ZPC1aa in advanced species. The N‐terminus of expanded ZPB1(a) or ZPC1(a) and liver‐expressed ZPB1a contains repeated units or low‐complexity regions to form ...
Tian Gao, Suying Ma, Shiyi Zhang, Fan Bai, Lingyao Gan, Wenjing Tao, Feilong Wang, Deshou Wang, Lina Sun   +8 more
wiley   +1 more source

The role of chromosomal translocation in the formation of an extraordinary oncogene

Джамила Шагайратовна Полатова, Margarita Gildieva, Akhmad Madaminov, А. V. Savkin, A. I. Nurzhabov, Н.К. Асамединов, D. А. Ibragimova, S. K. Nasirov   +7 more
openalex   +2 more sources

Genocopy of EVI1‐AML with paraneoplastic diabetes insipidus: PRDM16 overexpression by t(1;2)(p36;p21) and enhancer hijacking

British Journal of Haematology, EarlyView.
Summary Diabetes insipidus (DI) in patients with acute myeloid leukaemia (AML) and chromosome 3q alterations (EVI1/PRDM3/MECOM overexpression) constitutes a poorly understood paraneoplasia. A 44‐year‐old patient presented with clinical and morphological features of this syndrome but, surprisingly, disclosed the rare translocation t(1;2)(p36;p21), with ...
Julian List, Etienne Sollier, Fiona Brown‐Burke, Katherine Kelly, Dietmar Pfeifer, Valeria Shlyakhto, Kristina Maas‐Bauer, Milena Pantic, Christoph Plass, Michael Lübbert   +9 more
wiley   +1 more source

The impact of scaRNA12 deregulation on p53‐mediated cellular stress response in B‐cell precursor acute lymphoblastic leukaemia

British Journal of Haematology, EarlyView.
Summary Small nucleolar ribonucleic acids (snoRNAs) are a class of small non‐coding RNAs involved in the post‐transcriptional modification of ribosomal RNAs (rRNA) and small nuclear RNAs (snRNA). Mounting evidence indicates that specific snoRNAs are drivers of oncogenesis, but their role in B‐cell precursor acute lymphoblastic leukaemia (BCP‐ALL) is ...
Martijn W. C. Verbeek, Mathijs A. Sanders, Dwin G. B. Grashof, Remco M. Hoogenboezem, Iris van Zuijen, Annemarieke Bos, Trui van Gulck, Rosan Olsman, Rishov Mukhopadhyay, Eric M. J. Bindels, Peter J. M. Valk, Harmen J. G. van de Werken, Vincent H. J. van der Velden, Stefan J. Erkeland   +13 more
wiley   +1 more source