Results 341 to 350 of about 982,148 (390)
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2018
The sex chromosomes (gonosomes) are different, and sex chromosome translocations need to be considered separately from translocations between autosomes. A sex chromosome can engage in translocation with an autosome, with the other sex chromosome, or even with its homolog.
R. J McKinlay Gardner, David J. Amor
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The sex chromosomes (gonosomes) are different, and sex chromosome translocations need to be considered separately from translocations between autosomes. A sex chromosome can engage in translocation with an autosome, with the other sex chromosome, or even with its homolog.
R. J McKinlay Gardner, David J. Amor
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Molecular analysis of the t(14;18) chromosomal translocation in malignant lymphomas.
New England Journal of Medicine, 1987One of the most common karyotypic abnormalities is the t(14;18) translocation, which is found in many lymphomas that have a characteristic follicular morphology.
L. Weiss +3 more
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Hereditary renal-cell carcinoma associated with a chromosomal translocation.
New England Journal of Medicine, 1979MANY forms of human cancer tend to occur in families.1 Environmental causes of familial cancer often cannot be identified, and, by exclusion, a hereditary mechanism is postulated on the basis of pe...
A. Cohen +6 more
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Nondisjunction of a translocation-chromosome t(4;13)
Human Genetics, 1981We have studied a male infant with multiple congenital anomalies due to a double derivative chromosome 13 resulting from an inherited balanced reciprocal translocation t(4;13)(q23;q12).
M. Westmeier +5 more
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Histone influences on chromosomal translocations [PDF]
Nature Reviews Genetics, 2015 A new report shows that histone modification patterns influence the occurrence of chromosomal translocations.
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DNA Repair and Chromosomal Translocations
2015The balance between DNA damage, especially double strand breaks, and DNA damage repair is a critical determinant of chromosomal translocation frequency. The non-homologous end-joining repair (NHEJ) pathways seem to play the major role in the generation of chromosomal translocations.
Purvi M. Kakadia, Stefan K. Bohlander
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Complex chromosomal translocations in the Philadelphia chromosome leukemias
Cancer Genetics and Cytogenetics, 1991Joining of the BCR and ABL genes is an essential feature of the group of human leukemias characterized by the Philadelphia chromosome and there is recent evidence that the human BCR-ABL fusion gene induces leukemia in experimental animals. Joining of these two genes is the result of cytogenetic translocation, usually the t(9;22)(q34;q11), but sometimes
Christine M. Morris, Peter H. Fitzgerald
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The mystery of chromosomal translocations in cancer
Cytogenetic and Genome Research, 2007Chromosomal translocations in human cancer may result in products that can be suppressed by targeting drugs. An example is bcr-abl tyrosine kinase in chronic myelogenous leukemia that can be treated with imatinib mesylate. However, the mechanisms of translocations or exchanges of chromosomal segments are virtually unknown.
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Translocation chromosome karyotypes of the Robertsonian translocation carriers' embryos
Fertility and Sterility, 2010To explore the translocation karyotypes of the Robertsonian translocation (RT) carriers' embryos in their preimplantation genetic diagnosis (PGD) cycles.Retrospective.University-affiliated IVF center.A total of 35 RT carrier couples underwent 39 blastomere PGD cycles from August 2005 to June 2008.The PGD analysis of embryos.Meiotic segregation patterns
Liu Ping +4 more
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Genomics, 1998
Cleft lip with or without cleft palate is a common birth defect that is genetically complex. The nonsyndromic forms have been studied genetically using linkage and candidate-gene association studies with only partial success in defining the loci ...
K. Yoshiura +6 more
semanticscholar +1 more source
Cleft lip with or without cleft palate is a common birth defect that is genetically complex. The nonsyndromic forms have been studied genetically using linkage and candidate-gene association studies with only partial success in defining the loci ...
K. Yoshiura +6 more
semanticscholar +1 more source