Results 41 to 50 of about 83,206 (95)

A balanced complex chromosomal rearrangement (BCCR) in a family with reproductive failure [PDF]

open access: yes, 2017
Balanced complex chromosomal rearrangements are very rare events in the human population. Translocations involving three or more chromosomes frequently lead to a severe reproductive impairment secondary to meiotic disturbance in males and to chromosomal ...
Blouin, J.L.   +5 more
core  

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles [PDF]

open access: yes, 1996
Notch is a highly conserved transmembrane protein that is involved in cell fate decisions and is found in organisms ranging from Drosophila to humans. A human homologue of Notch, TAN1, was initially identified at the chromosomal breakpoint of a subset of
Aster, Jon C.   +6 more
core  

Mitotic antipairing of homologous and sex chromosomes via spatial restriction of two haploid sets. [PDF]

open access: yes, 2018
Pairing homologous chromosomes is required for recombination. However, in nonmeiotic stages it can lead to detrimental consequences, such as allelic misregulation and genome instability, and is rare in human somatic cells.
Hua, Lisa L, Mikawa, Takashi
core   +1 more source

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