Results 51 to 60 of about 986,967 (334)

The spectrum of chromosomal translocations in the Arab world: ethnic-specific chromosomal translocations and their relevance to diseases

Chromosoma, 2022
Abstract Chromosomal translocations (CTs) are the most common type of structural chromosomal abnormalities in humans. CTs have been reported in several studies in the Arab world, but the frequency and spectrum of these translocations are not well characterized.
Hadeel T. Zedan, Fatma H. Ali, Hatem Zayed   +2 more
openaire   +3 more sources

Analysis of cell mutation types of colorectal neuroendocrine tumors [PDF]

Jichu yixue yu linchuang
Objective To investigate the mutation types of colorectal neuroendocrine tumors(NETs) and better understand the pathogenesis of colorectal nets. Methods Patients undergoing colorectal NETs surgery were recruited, colorectal NETs and corresponding ...
WANG Tingting, GUO Dan, LU Junyang, XU Lai, DONG Haitao, LIN Dianxin, XIAO Yi
doaj   +1 more source

The Origin and Evolution of Chromosomal Reciprocal Translocation in Quasipaa boulengeri (Anura, Dicroglossidae)

Frontiers in Genetics, 2020
Chromosomal rearrangements have long fascinated evolutionary biologists for being widely implicated in causing genetic differentiation. Suppressed recombination has been demonstrated in various species with inversion; however, there is controversy over ...
Yun Xia, Xiuyun Yuan, Xiuyun Yuan, Wei Luo, Wei Luo, Siqi Yuan, Xiaomao Zeng   +6 more
doaj   +1 more source

Rhabdomyosarcoma: Advances in Molecular and Cellular Biology. [PDF]

, 2015
Rhabdomyosarcoma (RMS) is the most common soft tissue malignancy in childhood and adolescence. The two major histological subtypes of RMS are alveolar RMS, driven by the fusion protein PAX3-FKHR or PAX7-FKHR, and embryonic RMS, which is usually ...
Duan, Zhenfeng, Guo, Wei, Hornicek, Francis J, Mankin, Henry J, Shen, Jacson K, Sun, Xin   +5 more
core   +3 more sources

High-Risk Microgranular Acute Promyelocytic Leukemia with a Five-Way Complex Translocation Involving PML-RARA

Case Reports in Hematology, 2015
Acute promyelocytic leukemia (APL) is classically characterized by chromosomal translocation (15;17), resulting in the PML-RARA fusion protein leading to disease. Here, we present a case of a 50-year-old man who presented with signs and symptoms of acute
Benjamin Powers, Diane Persons, Deepthi Rao, Janet Woodroof, Tara L. Lin   +4 more
doaj   +1 more source

An update of preimplantation genetic diagnosis in gene diseases, chromosomal translocation, and aneuploidy screening

Clinical and Experimental Reproductive Medicine, 2011
Preimplantation genetic diagnosis (PGD) is gradually widely used in prevention of gene diseases and chromosomal abnormalities. Much improvement has been achieved in biopsy technique and molecular diagnosis.
Li-Jung Chang, Shee-Uan Chen, Yi-Yi Tsai, Chia-Cheng Hung, Mei-Ya Fang, Yidi Su, Yu‐Shih Yang   +6 more
semanticscholar   +1 more source

Wheat-barley hybridization – the last forty years [PDF]

, 2013
Several useful alien gene transfers have been reported from related species into wheat (Triticum aestivum), but very few publications have dealt with the development of wheat/barley (Hordeum vulgare) introgression lines. An overview is given here of
A Blanco, A Cabrera, A Cseh, A Cseh, A Farkas, A Kruse, A Löve, A Löve, A Martín, A Martín, A Martín, A Martín, A Martín, A Mujeeb-Kazi, A Mujeeb-Kazi, A Sepsi, AC Martín, AKMR Islam, AKMR Islam, AKMR Islam, AKMR Islam, AKMR Islam, AKMR Islam, AKMR Islam, AKMR Islam, AKMR Islam, B Wojciechowska, B Wojciechowska, C Doré, C Nakamura, CC Chu, CH Park, D Bai, D Villegas, DA Kerckhoffs, DJ Allendorf, DR Dewey, E Clauss, E Clauss, ED Nagy, ER Sears, ER Sears, ER Sears, G Fedak, G Fedak, G Fedak, G Fedak, G Fedak, G Fedak, G Fedak, G Galiba, G Kimber, Gabriella Linc, GE Hart, GS Sethi, H Bilgic, H Zou, HC Sharma, I Linde-Laursen, I Schubert, IR Barclay, J Fernandez-Escobar, J Jiang, J Lima-Brito, JA Fernandez, JB Thomas, JD Sherman, JI Cubero, JM Surikov, K Kruppa, K Murai, K Sakai, KC Armstrong, KF Mayer, KFX Mayer, L Junming, L Malysheva, LA Pershina, LA Pershina, LA Pershina, LS Dahleen, M Molnár-Láng, M Molnár-Láng, M Molnár-Láng, M Molnár-Láng, M Molnár-Láng, M Molnár-Láng, M Molnár-Láng, MD Gale, Márta Molnár-Láng, N Serizawa, P Barcelo, P Suchánková, PJ Larkin, PK Gupta, PP Jauhar, R Bothmer, R Bothmer, R Riley, R Riley, RA Burton, RA Finch, RJ Henry, S Cho, S Griffiths, S Islam, S Nasuda, S Svitashev, S Taketa, S Taketa, S Taketa, S Taketa, SB Chang, T Ashida, T Koba, T Koba, T Schwarzacher, TR Endo, V Chapman, VK Shumny, VK Shumny, Y Ya-Ping, É Szakács, É Szakács, É Szakács, Éva Szakács   +125 more
core   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

An infant with trisomy 9p and partial trisomy 12p derived from maternal balanced translocation: A case report and literature review

Journal of International Medical Research
We present here, a case of a neonate with an unbalanced chromosomal translocation due to a maternal chromosomal translocation carriage that resulted in the presence of trisomy 9p combined with a partial trisomy 12p. Karyotype analysis was performed using
Shengjin Ming, Zhumei Zhou, Yao Huang, Ying Huang, Jinping Zhong, Yingli Li   +5 more
doaj   +1 more source

Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4/ligase IV during chromosomal translocation formation

Nature Structural &Molecular Biology, 2010
Chromosomal translocations in hematologic and mesenchymal tumors form overwhelmingly by nonhomologous end-joining (NHEJ). Canonical NHEJ, essential for the repair of radiation-induced and some programmed double-strand breaks (DSBs), requires the Xrcc4 ...
Deni̇z Şi̇mşek, M. Jasin
semanticscholar   +1 more source